Erik Danen is looking at how to inhibit tumours that do not respond well to medicine – and he is making some headway. The Professor of Cancer Drug Target Discovery studies the interaction between tumour cells and their surroundings. Inaugural lecture on Friday 10 May.

Researchers at LED3 are working together with biopharmaceutical company Galapagos to develop software for use in early drug discovery (funded by NWO). This software is able to design molecules with several simultaneously optimized characteristics and will also take prediction reliability into consideration…

Key publications of the Computational Drug Discovery group

Exhibition

Andrew Sorensen received the award for his work on the origins of fire-making, especially for his dissertation

LUCL is glad to announce that two of its members have been awarded an NWO Vrije Competitie Grant.

Eduard Fosch-Villaronga from Leiden University has been awarded a Starting Grant by the European Research Council (ERC). This grant of 1.5m euros enables talented early-career scholars to start their own pioneer project, lead a research team, and implement their best ideas at the frontiers of their…

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Sound Arguments is an innovative laboratory-atelier for creative artists and researchers dealing with sound. Presented by the Orpheus Institute, Ghent (BE), and the Academy of Creative and Performing Arts, University of Leiden (NL), Sound Arguments transcends the boundaries of art school or conservatory,…

Workshop

Comparison between babies and song-birds when they are learning a non-existent language—a study of this kind has never been tried before. But this is what Claartje Levelt, Carel ten Cate (Leiden University) and Jelle Zuidema (University of Amsterdam) are attempting.

Joost Beltman (LACDR, Leiden University) has provided novel insights in the way T cells migrate towards virus-infected cells. This was accomplished by a combination of experimental research in the group of Ton Schumacher (Dutch Cancer Institute, NKI) and computer simulations in collaboration with Rob…

Handbook of Signal Processing Systems is organized in four parts. The first part motivates representative applications that drive and apply state-of-the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these applications;…

Conferences, Workshops and Lectures showcasing research and tools in Digital Humanities.

Tuberculosis stands as one of the most lethal infectious diseases worldwide. A significant challenge in combatting tuberculosis lies in the emergence of antibiotic resistance triggered by genetic alterations, commonly known as mutations. These mutations can diminish the responsiveness to antibiotics,…

More severe droughts that will also last longer: this will primarily be a problem for irrigated croplands, as discovered by environmental scientist Qi Chen. Mixed forests with a variety of plant species will be the least vulnerable. Chen compared the effects of drought on different ecosystems across…

Prof. Marcel Reinders is a data science specialist at Delft University of technology. Using smart algorithms, he searches for links in complex data. For example, he studies patterns in DNA that lead to aberrant cell behaviour. This knowledge will help detect serious diseases such as Alzheimer's and…

For the first time, an international group of astronomers have seen the heat glow of two ice giant planets colliding. They could also observe the resultant dust cloud move in front of the parent star several years later. Led by Leiden astronomer Matthew Kenworthy, they monitored the star's brightness…

How is it that some covid-19 patients are affected much worse than others? Can we predict beforehand which of them will develop critical symptoms Professor Thomas Hankemeier, together with a diverse consortium of universities, academic hospitals and industrial partners, is looking for the answers to…

This project on the role of FoxPs in vocal perception and production learning is part of nine PhD-positions funded by the NWO Gravitation Programme which was granted to the Dutch Research Consortium 'Language in Interaction'

When you become very good at one thing, that sometimes comes at the expense of something else. Such trade-offs also apply to bacteria. When becoming more resistant to one antibiotic, bacteria can sometimes become more sensitive to another. Linda Aulin, PhD candidate in the pharmacology group of Coen…

Before patients can take a pill, scientists often spend years in the lab developing and testing a candidate drug. That often includes experiments with laboratory animals. As head of the rodent facility, Ilze Bot and her colleagues ensure that these experiments are conducted in an ethically responsible…

Giving an incorrect answer as a student in a packed lecture hall can be nerve-wracking. But with Pharmacology teacher Rob van Wijk, you don’t need to worry about that. ‘He creates a comfortable and safe atmosphere,’ his students say. They have nominated him for the Leiden Science Teacher Award.

How does a farmer decide if his cow is a prize winner? An anthropologist studying these farmers should not only look at the farmers themselves, but should in particular learn how they see the world. This is what Cristina Grasseni, the new Professor of Anthropology contends. Inaugural address on 30 O…

Seven researchers from Leiden University have been awarded an ERC Starting Grant. This will enable them to start their own project, build their research team and put their best ideas into action.

All over Europe you will find ethnographic museums with large collections of indigenous objects from Latin America. These collections shaped the image of native populations in the European mind. An ERC Starting Grant allows Dr Martin Berger to look at the bigger picture, contextualizing individual collections…

About 90 per cent of Austronesian and Papuan languages are under threat of soon becoming extinct. Marian Klamer is the only professor in the world who researches both these language groups. She records languages before they disappear and sheds new light on the history of Indonesia. Inaugural lecture…

When it comes to literature, people mostly talk about what characters see or hear. Rarely is it about what they smell. That’s a shame, thinks university lecturer Jan van Dijkhuizen. He has been awarded an Open Competition grant from NWO to expand academic knowledge about scent in literature, and to…

How do molecules originate and evolve in space? And how does that ultimately determine the chemical composition of planets and their atmospheres? The Dutch Astrochemistry Network (DANIII) receives 1.6 million euros from NWO to find out. A large group of Leiden astronomers and chemists is contributing:…

The current projects of the Molecular Physiology group focus on proteins of the endocannabinoid system, kinases and antibacterial targets. MSc- and BSc-students can contact Jessica van Krimpen-Kraaijenoord to apply for research internships.

Animal Sciences’ contributions to the Evolution & Biodiversity research theme include evo-devo research, the evolution of cognitive and behavioural traits, and the evolutionary mechanisms of stress adaptation. This research involves both indoor and outdoor studies.

Computers are becoming ever more powerful and are taking on more complex tasks. The Leiden Institute of Advanced Computer Science (LIACS) contributes to revolutionary scientific research and applies the latest inventions in the field, offering answers to today’s questions of society.

The Leiden Institute of Advanced Computer Science (LIACS) of Leiden University proudly establishes the Blaise Pascal chair. The chair applies for one year and is meant to strengthen the cooperation of the Leiden computer science research with foreign institutes.

Lecture

The Astronomy and Data Science master’s specialisation at Leiden University combines advanced Astronomy courses with relevant courses from the Computer Science programme at Leiden University.

Lecture

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

Lecture, Studium Generale

Researchers at LIACS are working to devise the computers of tomorrow that will be the backbone of the Cloud and Edge computing paradigms as well as the Internet of Things. In this respect, we are involved in research and development of high performance computing systems, embedded & real-time computing…

An international team of astronomers has revealed the first 'chemical profile' of an exoplanet's atmosphere. The team, including Leiden astronomer Yamila Miguel and provenda Amy Louca, made the profile using so-called Early Release Science data from the James Webb Space Telescope. The results have been…

The glycosylation reaction is a pivotal reaction in creating new and complex oligosaccharides.

Can we provide the Dutch government with an integrative framework, wherein the various policies can be placed and the need for further measures can be identified?

Students in our Astronomy programme are trained by leading experts in cutting-edge astronomical research. We incorporate in our educational programme observations and data from the world’s foremost ground- and space-based telescopes as well as theoretical, computational and astrochemical modelling,…

A cancer pill, preferably without severe side effects, is something we’d all welcome. Is it a matter of time before such a pill is a reality? We put this question to three Leiden researchers and asked how they themselves are contributing to new cancer treatments.

The Dick Stufkens Prize 2020 for the best PhD thesis of the Holland Research School of Molecular Chemistry has been awarded to Dr Mark Koenis. Koenis graduated 21 February with the distinction cum laude on his thesis 'Advanced Spectra Analysis to Determine Complex Structure and Chirality'. He describes…

Streptomycetes are similar to moulds, but these bacteria live in the soil. They are very popular in biotechnology because they produce a great many antibiotics and enzymes. Gilles van Wezel will be using his Vici subsidy to study ways of increasing their production.

From studying molecules in the blood of corona patients to developing a new concept for vaccines. The Leiden Academic Centre for Drug Research (LACDR) has transformed many ongoing projects into Covid research projects. Hubertus Irth, scientific director of LACDR, talks about the role of his institute…