180 zoekresultaten voor “she barrie repair” in de Publieke website
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Barrie SanderFaculteit Governance and Global Affairs
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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A novel formulation for skin barrier repair : from ex vivo assessment towards clinical studies
The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.
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metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
The research presented in this thesis explores the chemotherapeutic potential of metal-based compounds as chemotherapy agents, with an initial focus on the synthesis and DNA interaction studies of platinum and palladium compounds utilizing the [Pt(bapbpy)]2+ scaffold. The study identifies intercalation…
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Contemporary International Criminal Law After Critique
In dit artikel onderzoeken de auteurs hoe het internationaal strafrecht overgaat naar een ‘post-kritische’ fase en bekijken ze het potentieel voor emancipatoire hervorming.
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Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
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High fidelity DNA replication and repair
Promotie
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Elective Abdominal Aneurysm Repair Challenges remain
Promotie
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Enhancing epicardial EMT to repair the heart
Promotie
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Dance Improvisation: Soil Connections, Gleaners and the Worms
Kunst en vrije tijd, Kunst en vrije tijd
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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The Invisible History of the United Nations and the Global South - INVISIHIST
The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…
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Control of replication associated DNA damage responses by Mismatch Repair
Promotie
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Unravelling molecular mechanisms in transcription-coupled nucleotide excision repair
Promotie
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Nucleotide excision repair: from molecular mechanisms to patiënt phenotypes
Promotie
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Environmental and health impact of informal e-waste recycling
The majority (80%) of e-waste generated globally are recycled informally in developing countries.
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Amerikaans buitenlands beleid en liberalisme
The NWO-funded Vidi project “American foreign policy and liberalism” challenges the idea that the United States has created and sustained a “liberal international order” since World War II. It instead explores the ways in which illiberal ideologies – such as those underpinning racial hierarchy at home…
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Creative writing (English spoken)
Kunst en vrije tijd, Kunst en vrije tijd
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An introduction to poetry (English spoken)
Kunst en vrije tijd, Kunst en vrije tijd
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Mechanisms underlying mutational outcomes of DNA double-strand break repair
Promotie
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Exposure and health Assessment of Persistent Organic Pollutants (POPs) at e-waste recycling site among workers in the informal sector in Nigeria
Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Machine learning and computer vision for urban drainage inspections
Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.
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Alumni
Sinds 2009 behaalden 90 kandidaten hun doctoraat in Creative en Performing Arts. Op deze pagina een overzicht van ACPA's alumni.
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Korean Painting: Discover the Timeless Beauty of Oriental Landscape Painting
Kunst en vrije tijd, Kunst en vrije tijd
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Global Challenges
In the spring of 2025, Studium Generale will host several Global Challenges lectures at Leiden University College The Hague. We begin on December 10, 2024, International Human Rights Day, with a panel discussion about children's rights in conflict zones, focusing on the right to education during and…
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metal-based chemotherapeutic agents for targeted DNA interactions or DNA repair pathway modulation
Promotie
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Workshop The Art of Journaling
Kunst en vrije tijd, Kunst en vrije tijd
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Rituals of Birth, Circumcision, Marriage, and Death among Muslims in the Netherlands
Migration imposes special pressures on the meaning, experience and organization of lifecycle rituals. These pressures are felt most strongly by Muslim migrants to Western Europe. In this innovative study, Nathal M. Dessing examines the effects of migration on the life cycle rituals of Moroccan, Turkish…
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“This Path Is Full of Thorns”: Narrative, Subjunctivity, and HIV in Indonesia
In this article, Samuels focuses on the active fostering of subjunctivity in processes of narrative worldmaking. Drawing extensively from the narrative of an HIV‐positive woman in Indonesia, she shows that by subjunctively leaving open multiple narrative trajectories and future possibilities, individuals…
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Synthetic Methodology Towards ADP-Ribosylation Related Molecular Tools
Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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Journaling for Beginners: Yes, You CAN Say It Like It Is
Kunst en vrije tijd, Kunst en vrije tijd
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Doe mee aan ons onderzoek naar betere zorg voor depressieve jongeren
De vier Leidse promovendi Loes Janssen, Mirjam Wever, Dianne van der Heide en Lisanne van Houtum werken mee aan onderzoek om depressieve jongeren te helpen met een betere diagnostiek. Doe je mee? Ook ouders van jongeren zonder psychische klachten zijn welkom.
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Student reviews of our courses
Read all about the experiences of our students who followed one of the Academic Language Center's (online) courses in the past semester.
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Dekoloniseren van Internationale Rechtvaardigheid
Wereldwijd is er een groeiende beweging om universiteitscurricula te dekoloniseren. Zowel onderwijsstaf als studenten zoeken naar manieren om bestaande epistemische hiërarchieën in het hoger onderwijs kritisch te evalueren. Dit onderzoekproject richt zich op het ontrafelen van wat dekoloniseren betekent…
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De tweede golf: Onderzoek doen ten tijde van corona
Dinsdag 13 oktober zaten 7,4 miljoen mensen voor de televisie voor een nieuwe persconferentie. De conclusie: een gedeeltelijke lockdown om de tweede golf van het coronavirus in te dammen. Hoe gaan onderzoekers aan de Universiteit Leiden hiermee om? Hoe kan onderzoek door blijven lopen en veiligheid…
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AI en de klimaattransitie: een 'match made in heaven'?
Kunstmatige intelligentie wordt vaak verbeeld als een technisch redmiddel in de strijd tegen klimaatverandering. Maar er kleven risico’s aan, zegt Barrie Sander.
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Pascal Professor 2015
In 2015 the Pascalchair of the Faculty of Science, Universiteit Leiden and in particular of Leiden Institute of Advanced Computer Science, is held by Prof. Dr. Natasa Jonoska, University of South Florida, Tampa, USA.
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Vote for Discoverer of the Year 2017
Suzan Verberne is nominated by the Leiden Institute of Advanced Computer Science (LIACS) to be granted the C.J. Kok Public Award, also known as the award for the ‘Discoverer of the Year’.
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Conversation with Dr Graça Machel: intergenerational justice from a human rights perspective
Almost three years after receiving her honorary doctorate, Dr Graça Machel returned to Leiden University. Over the course of two days she spoke with students, researchers, and other interested persons, about human rights – particularly those of women and children – in a world in which these are continually…
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Roeland van der Rijst
Evaluatie in actie: ontwikkeling en implementatie van een mobiele applicatie voor tussentijdse feedback en onderwijsevaluaties.
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An introduction to life-story writing (English spoken)
Kunst en vrije tijd, Kunst en vrije tijd
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Hendrik Casimir Prize 2016 voor Andrea Peña en Jorrit Hortensius
Op de LION/Sterrewacht nieuwjaarsborrel heeft prof. Tjerk Oosterkamp de 2016 Hendrik Casimir Prize uitgereikt aan natuurkundestudenten Andrea Peña (Leiden) en Jorrit Hortensius (Delft). The Casimir Research School deelt jaarlijks de Hendrik Casimir Prize uit aan de beste masterstudenten in (technische)…
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Promotie R. Rissmann
Op dinsdag 17 maart promoveert Robert Rissmann van het LACDR. De titel van zijn proefschrift luidt