The human body consists of hundreds, perhaps thousands of different types of cells, each with different morphologies and functions, despite having the same genome.

Promotors: Prof.dr. P.J. Punt, Prof.dr. C.A.M.J.J. van den Hondel

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Promotor: P.M. Brakefield

Are you planning to conduct clinical research in the Netherlands? In this online course, you are introduced to legislation and procedures on clinical research in the Netherlands. It will help you prepare and submit your research file efficiently. The first three themes ‘The Dutch Review System’ , ‘The…

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

Dit proefschrift behandelt de vraag of er een level playing field is tussen Europese beleggers die beleggen in EU-beleggingsinstellingen en Europese beleggers die beleggen in Amerikaanse beleggingsinstellingen en, als dit niet het geval is, of de Europese wetgever aanvullende regelgeving zou moeten…

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.

In deze bundel wordt de regulering behandeld van politieke partijen in de post-communistische EU-landen, met name Bulgarije, Croatië, Tsjechië, Estland, Hongarije, Letland, Litouwen, Polen, Slowakije, Slovenië en Roemenië.

Op 10 oktober 2019 verdedigde Laure d'Hondt haar proefschrift 'Addressing Industrial Pollution in Indonesia. The Nexus between Regulation and Redress seeking'. Het promotieonderzoek is begeleid door promotor prof.dr. A.W. Bedner.

Matthias Haentjens, Jouke Tegelaar en Dorine Verheij schreven het hoofdstuk Financial Market Regulation and Supervision, dat recentelijk is gepubliceerd in het belangwekkende handboek The Law of the European Union (voorheen Kapteyn & VerLoren van Themaat).

Promotor: J.M. Memelink

In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Dit proefschrift betreft een interpretatief onderzoek naar de wijze waarop leraren hun dagelijkse leraar-leerling interacties interpreteren in termen van het belang van hun leerlingen.

Op 12 september 2019 verdedigde Michiel Rhoen zijn proefschrift 'Big Data, Big Risks, Big Power Shifts: Evaluating the General Data Protection Regulation as an instrument of risk control and power redistribution in the context of big data'. Het promotieonderzoek is begeleid door promotoren prof.dr.mr.…

Op 11 mei 2017 vond ter gelegenheid van zijn eerste lustrum het lustrumcongres van Hazelhoff Centre for Financial Law plaats met als thema ‘Public and Private Regulation of Financial Markets’.

The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.

Op 13 februari 2017 sprak professor Matthias Haentjens bij de Griekse centrale bank op het congres “Proportionality in European Banking Regulation”. Dit congres werd georganiseerd door de centrale bank van Griekenland in samenwerking met de Universiteit van Piraeus en het European Banking Institute…

De ECPR summer school over Interest Group Politics viert zijn 10-jarig jubileum. Om deze speciale editie te vieren, omvat de zomerschool van dit jaar vele gerenommeerde onderzoekers en professoren uit de hele wereld. Als onderdeel van het jubileum wordt bovendien een buitengewone eendaagse conferentie…

Op vrijdag 2 december 2016 heeft een internationale onderzoeksconferentie plaatsgevonden in Leiden. Deze was georganiseerd door de onderzoeksgroep van Coherent Privaatrecht. De conferentie droeg de titel “Private law and market regulation – interaction, interference or inconsistency?”. Het centrale…

Op vrijdag 2 december vindt in Leiden een internationale, multidisciplinaire conferentie plaats gecentreerd rond onderzoek over burgerlijk recht en marktregulering. De conferentie draagt de titel “Private law and market regulation – interaction, interference or inconsistency?” en wordt georganiseerd…

In oktober werd Sophie Starrenburg gekozen tot lid van het coördinerende comité van de ESIL ‘Interest Group on the International Law of Culture’. Ze zal hierin samenwerken met Giovanni Carlo Bruno (Italian National Research Council), Andrzej Jakubowski (Polish Academy of Sciences) en Lucas Lixinski…

All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).

Dit boek, geschreven door prof. mr. Bob Wessels (em.) en Ilya Kokorin LLM, , beschrijft en analyseert de Europese insolventieverordening (herschikt) ('EIR 2017’) die inwerking is getreden in juni 2017.

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

De Commissie Ethiek heeft als hoofdtaak alle voorgenomen gedragswetenschappelijk onderzoek van het Instituut Pedagogische Wetenschappen, te toetsen op criteria van ethisch verantwoord wetenschappelijk handelen.

Salicylic acid (SA) is a plant hormone, which is involved in the defense responses to pathogens and to abiotic stress, and in the regulation of plant growth and development.

In 2021 heeft het NCSC de Universiteit Leiden gevraagd om een rapid review uit te voeren naar best practices en mogelijkheden voor vervolgonderzoek over de integratie van gedragswetenschappen in security by design methodologieën en projecten. Dit academische veld wordt security by behavioural design…

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

Op dinsdag 1 oktober 2019 ontving het Hazelhoff Centre for Financial Law voor de negentiende Hazelhoff Guest Lecture Paul Sharma, managing director bij Alvarez & Marsal en co-head van praktijkgroep European Financial Industry Regulatory Advisory Services.

Hieronder vind je een overzicht van de publicaties van LAPP.

Promotor: Prof.dr. R. Verpoorte, Co-Promotores: N.R. Mustafa, A.E. Schulte

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.

The soil-dwelling, filamentous bacteria of the genus Streptomyces are renowned for their production of useful secondary metabolites including antibiotics. The work described in this thesis provides new insights on the role and regulation of antibiotic production and resistance in these bacteria.

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

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A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.

The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.