1,683 zoekresultaten voor “teaching in have education” in de Publieke website
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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Liposome-based synthetic long peptide vaccines for cancer immunotherapy
Promotores: Wim Jiskoot; Ferry Ossendorp
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Evaluation of the environmental impact of products (EIPRO)
Identification of the products or product groups that have the greatest environmental impact from a life-cycle perspective using environmentally extended input-output analysis.
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Predicting the future: Predictive control for astronomical adaptive optics
The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.
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Business incubators: the impact of their support
A New Technology-Based Firm (NTBF) is a significant enabler of job creation and a driver of the economy through stimulating innovation.
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Bayesian learning: challenges, limitations and pragmatics
This dissertation is about Bayesian learning from data. How can humans and computers learn from data?
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Exploring strange new worlds with high-dispersion spectroscopy
Until the 1990s, the only known planets were those in our Solar System. Three decades later, several thousand exoplanets have been discovered orbiting stars other than the Sun, and substantial efforts have been made to explore these strange new worlds through spectroscopic analyses of their atmosphe…
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Evaluation of Different Design Space Description Methods for Analysing Combustion Engine Operation Limits
Promotor: Prof.dr. T.H.W. Bäck
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Convergent molecular evolution of toxins in the venom of advanced snakes (Colubroidea)
The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…
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Phenotypic engineering of photosynthesis related traits in Arabidopsis thaliana using genome interrogation
Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal
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Signalling pathways that control development and antibiotic production in streptomyces
Bacteria are highly complex and diverse organisms that have adapted to survive in ecological niches ranging from the most extreme to the most heterogeneous environments.
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Next generation bacitracin: reimagining a classic antibiotic
Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…
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Complex multiplication of abelian surfaces
Promotor: Peter Stevenhagen
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The dust and molecular gas in the torus of NGC 1068
An Active Galactic Nucleus (AGN) is a highly luminous region at the center of a galaxy, powered by the accretion into a supermassive black hole and emitting energy from radio waves to gamma rays, often outshining the host galaxy.
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Not so smooth after all: resolving dust and gas structures in protoplanetary disks
A large diversity of exoplanetary systems has been found, but it is still unclear what drives this diversity.
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Adaptive responses to environmental changes in Lake Victoria cichlids
Promotor: M.K. Richardson, Co-Promotor: F. Witte
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Reactivity of cobalt(II)-dichalcogenide complexes: correlation between redox conversion and ligand-field strength
The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.
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Automata-theoretic protocol programming
Promotor: F. Arbab
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Applying data mining in telecommunications
This thesis applies data mining in commercial settings in the telecommunications industry.
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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The effects of burying beetle social behaviours on interspecific interactions
This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.
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B cell modulation in atherosclerosis
Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.
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Peeking into the future: Fungi in the greening Arctic
Promotor: E.F. Smets, Co-promotor: J. Geml
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Self-Adjusting Surrogate-Assisted Optimization Techniques for Expensive Constrained Black Box ProblemsBagheri, S.
Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.
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Carcinogenicity of insulin analogues
Promotor: Prof.dr. B. van de Water
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Magnetic Resonance Force Microscopy and the Spin Bath
There are many interpretations of quantum mechanics, and ultimately experiments are needed to verify or falsify these interpretations.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Dynamics of coupled quantum systems
Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…
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Ecology and genomics of Actinobacteria and their specialised metabolism
Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.
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Gibbs Processes and Applications
Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.
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Studying the Benefits of Using UML on Software Maintenance: an Evidence-Based Approach.
Including modelling as part of software development appears to have various benefits.
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Novel formulations and delivery strategies for inactivated polio vaccines : new routes with benefits
This thesis describes the development of improved formulations and alternative delivery strategies for polio vaccination.
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The Miliuseae revisited: phylogenetic, taxonomic, and palynological studies in a major clade of Annonaceae
Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou
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Some case studies of random walks in dynamic random environments
Promotor: Promotor: W.Th.F. den Hollander, Co-promotor: V. Sidoravicius.
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Computational optimisation of optical projection tomography for 3D image analysis
Optical projection tomography (OPT) is a tomographic 3D imaging technique used for specimens in the millimetre scale.
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Giant barrel sponges in diverse habitats: a story about the metabolome
Marine sponges are important members of reef ecosystems, as they play ecological roles that are essential for the health of the reef.
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Group benefits from genomic instability: a tale of antibiotic warriors in Streptomyces
Streptomyces are filamentous bacteria that produce more than two-thirds of known antibiotics.
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Impact of low-carbon electricity development on carbon emissions in China
Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.
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Giant unilamellar vesicles: An efficient membrane biophysical tool and its application in drug delivery studies
Promotor: A. Kros
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Multi-dimensional feature and data mining
In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.
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Regulation of the arabidopsis AGC kinase PINOID by PDK1 and the microtubule cytoskeleton
Plants, are sessile organisms, have developed strategies to adapt to changes in their environment, in part by altering their growth and development.
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Political Muslims: Understanding Youth Resistance in a Global Context
An interdisciplinary collection of the best international scholarship on Muslim youth.
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Systems diagnosis in chronic disease: prediction and evaluation
Promotor: J. van der Greef, T. Hankemeier; Co-promotor: H.A. van Wietmarschen
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Aggravating matters: accounting for baryons in cosmological analyses
Three major cosmology-focused missions are planned for the next decade: the Euclid space telescope, the Vera C. Rubin Observatory in Chile, and the Nancy Grace Roman Space Telescope.
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Allosteric modulation and ligand binding kinetics at the Kv11.1 channel
Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman
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