Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

Taxonomy as a science has accumulated data and knowledge for more than 250 years.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

This work is dedicated to interpreting in cohomological terms the special values of zeta functions of arithmetic schemes.

Op 28 oktober 2021 verdedigde Hein van der Bruggen zijn proefschrift en behaalde daarmee de doctorstitel.

This dissertation focused on computational methods based on first principles calculations using the Density Functional Theory (DFT) framework. Emphasis was laid on affordable methods that can provide a tradeoff between computational expense and accuracy.

Cardiovascular disease is a major global burden and atherosclerosis is the main underlying pathological process.

There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…

Promotor: E.F. Smets, Co-promotor: J. Geml

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

Tin electrodeposition applications have rapidly evolved in the past 25 years.

This thesis describes the design, characterization and application of dextran based crosslinked network.

The lysosomal β-glucosidase named glucocerebrosidase (GCase) is a retaining β-glucosidase that hydrolyzes the glycosphingolipid glucosylceramide (GlcCer) to ceramide and glucose at acid pH.

Promotor: G.F.A. Kersten, W. Jiskoot, Co-promotor: B. Metz

Every organisms in the tree of life faces the same challenge: the length of its DNA exceeds the volume of the cell it needs to fit in. Several strategies have evolved to solve this problem, one of them being the expression of proteins that bind and organize the DNA.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

The mycorrhizal symbiosis is among the most widespread species interactions on Earth⁠. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries⁠.

Vancomycin is a last-resort antibiotic for the treatment of many Gram-positive bacterial infections, while remaining inactive against Gram-negative strains.

Promotor: W.Th.F. den Hollander Co-Promotor: F.M. Spieksma

Promotor: Prof.dr. I.A.G. Snellen, C.U. Keller

Promotores: W. Th. F. den Hollander, M.O. Heydenreich

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

In this work, we illustrate unconventional approaches towards the fabrication of edge functionalized graphene nanostructures and bidimensional architectures in polymeric and metallic supports, with an outlook towards molecular sensing devices.

Promotor: P.D. Grünwald

Promotores: E. van Dijk, G.R. de Snoo. Co-promotor: H. Staats

Promotor: Prof.dr. P.G.L. Klinkhamer, Co-Promotor: T.J. de Jong

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.

Promotor: Prof.dr. F.S. de Boer, Co-promotor: D. Clarke

Promotor: Prof.dr. M.L. van Hecke

How presence, abundance and enzymatic activities of AM and EM fungi differently affect soil carbon sequestration processes?

Synthetic microswimmers take an important place within the interdisciplinary field of active soft matter.

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

In this PhD-thesis several new and existing data science application are described that are particularly focused on applications for tax administrations.

Control of infectious diseases poses continuous challenges for human health.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency

Promotor: Prof.dr. T. Hankemeier, Prof.dr. J.C.T. Eijkel (Twente University)

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…

Promotor: Ed F. Deprettere, Co-promotor: Todor P. Stefanov

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

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Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.