Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Promotores: Prof.dr. M. Danhof, Prof.dr. D.R. Stanski

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.

What happens to electrical waves that have to cross gaps in insulation material around nerves in the human body

This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.

The research in this dissertation aims to optimise blood donation processes in the framework of the Dutch national blood bank Sanquin. The primary health risk for blood donors is iron deficiency, which is evaluated based on donors' hemoglobin and ferritin levels.

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

This thesis addresses the problem of designing performance and energy efficient embedded streaming systems, that is, systems which process a stream of input data coming from the environment and generate a stream of output data going into the environment.

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Met haar project WetSuite wil Meuwese AI-technieken die gebruikt kunnen worden om juridische overheidsdocumenten te analyseren toegankelijk maken voor een brede groep onderzoekers.

De Leidse masterstudent Arend Moerman heeft een tien gekregen voor zijn afstudeeronderzoek naar de simulatie van de chaotische interacties van drie zwarte gaten. Uit de simulaties blijkt dat lichtere zwarte gaten elkaar meestal wegslingeren, terwijl zwaardere vooral samensmelten. Het onderzoek, een…

Mosselen in mosselbedden vormen een patroon dat lijkt op de organisatie van moleculen en atomen in materialen als brons, staal of rubber. Dit gedrag kan dan ook worden beschreven met hetzelfde wiskundige model.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

Promotor: K.J. Batenburg

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

Promotores: A.P. IJzerman, H.W.T. van Vlijmen

The focus throughout this thesis will be on gathering fundamental studies of the detailed structure and composition of the electrode/electrolyte interface effect on the rate and mechanism of key electrocatalytic reactions.

This thesis considers multi-prover commitment schemes whose security is based on restrictions on the communication between the provers.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

It is an established fact that the Standard Model has to be extended to explain the so-called Beyond the Standard Model (BSM) phenomena: dark matter, matter-antimatter asymmetry of the Universe and neutrino flavour oscillations.

In this dissertation non-parametric Bayesian methods are used in the application of robotic vision.

Het ontwikkelen, gebruiken en evalueren van groepsopdrachten in het hoger onderwijs.

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

In this work, we attempt to answer the question:

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

This thesis explores Breaking of Ensemble Equivalence (BEE) in random graph models by examining the spectral properties of adjacency matrices. The goal is to identify spectral characteristics that differentiate random graph ensembles, enhancing the understanding of complex network structures and beh…

In het Scheepvaartmuseum van Amsterdam bevindt zich een getuigd model van een driemasterschip uit de tweede helft van de zestiende eeuw: het oudste scheepsmodel in de museumcollectie. Historicus Louis Sicking deed in opdracht van het museum onderzoek naar dit bijzondere object.

Nucleoid associated proteins maintain the architecture of the bacterial chromosome and regulate gene expression, hinting that their role as transcription factors may involve local three-dimensional chromosome re-modelling.

Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.

This thesis discusses the discovery potential of Intensity Frontier experiments.

Promotors: Prof.dr. J. Zaanen, Prof.dr.ir. H. Hilgenkamp

Shabaz Sultan en Simon Portegies Zwart, met de hulp van Vincent Icke, hebben één van de tien Surf Innovation Challenge Awards gewonnen voor hun onderzoek naar 'Interactive high-performance laboratory for Chaos'. De winnaars hebben een geldprijs van 10.000 euro ontvangen en krijgen 6 maanden (tot 1 juni…

De nieuwste Europese quantumcomputer komt in Nederland. De ict-coöperatie van Nederlandse onderwijs- en onderzoeksinstellingen SURF krijgt hiervoor financiering van het Europese EuroHPC-programma. Leidse onderzoekers hebben een belangrijke rol: zij ontwerpen de algoritmes en de machine learning routes,…

Material circularity and energy efficiency are highly relevant and intertwined issues for the transition towards a carbon-neutral and circular built environment. In the Netherlands, the building sector has been rendered a priority towards a circular and low-carbon society.

Promotor: Prof.dr. W.Th.F. den Hollander, Co-promotor: R. Fernandez.

Met de huidige marktregels is het behoorlijk risicovol om in groene energie te investeren, en dat staat de strijd tegen klimaatverandering in de weg. Dat schrijft milieuwetenschapper Oscar Kraan in zijn proefschrift. Promotie op 25 april.