This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Promotor: Roeland M.H. Merks

A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.

There is concern about the threat that nanoplastics (NPs) may pose to both wildlife and humans. This thesis explores the mechanisms of toxicity of polystyrene nanoparticles (PS-NPs) in chicken embryo.

The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…

Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.

The work in this thesis describes the fundamental role of Lkb1 as a conductor of metabolism-related processes in zebrafish larvae.

This thesis concerns the relation bettween the good reduction of Shimura varieties and the associated loop groups.

Promotor: Prof.dr. E Gittenberger, Co-Promotores: C.H.J.M. Fransen, B.W. Hoeksema

The transition to electric vehicles (EVs) reduces vehicle emissions to combat climate change. EVs raise concerns regarding the production of lithium-ion batteries and related emissions; while batteries can also provide energy storage services for the electricity system.

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.

This dissertation investigates the energy and material related impacts of the transition towards a low-carbon heating system in the Netherlands, in the context of its 2050 climate and circular economy policy goals.

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

Promotor: Prof.dr. G.R. de Snoo

Promotor: B.van de Water, Co-promotor: L.S.Price

Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…

Lysosomal glycosidases are acid hydrolases that fragment glycoconjugates in lysosomes.

Autophagy is a fundamental degradative process, maintaining cellular homeostasis and functions in host defense against intracellular pathogens, including mycobacteria and Salmonella.

In this article, Samuels focuses on the active fostering of subjunctivity in processes of narrative worldmaking. Drawing extensively from the narrative of an HIV‐positive woman in Indonesia, she shows that by subjunctively leaving open multiple narrative trajectories and future possibilities, individuals…

Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe

The key characteristic of active matter is the motion of an emergent collection (such as a flock of birds), which is driven by the consumption of energy by its active components (i.e. individual birds).

Promotor: H.V.J. Linnartz

What impact does a mid-season wildfire have on grassland invertebrates?

Promotores: G.W. Canters, T.J. Aartsma

n this PhD thesis, the recombination of different atomic lattices in stacked 2D materials such as twisted bilayer graphene is studied. Using the different possibilities of Low-Energy Electron Microscopy (LEEM), the domain forming between the two atomic layers with small differences is studied.

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

Quantummechanica voor iedereen

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

1: What is the relative importance of alfa and beta biodiversity in polar ecosystems, and how does intraspecific variation influence this? 2: How can we use remote sensing to determine functional biodiversity (within communities) in polar ecosystems? 3: Temporal and spatial scales of functional biodiversity:…

It is a common technique in global optimization with expensive black-box functions to learn a surrogate-model of the response function from past evaluations and use it to decide on the location of future evaluations.

Promoter: Ed F. Deprettere, Co-promoter: Todor P. Stefanov

The mission of our group is understanding how science communication works to improve the interaction between science and society. We believe better science communication can improve our society and engage many different groups with science, also improving science.

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

Promotor: Prof.dr. L.J. Slikkerveer

Promotor: K.J. Batenburg

Electrons in a crystal lattice have properties that may differ from those of a free electron in vacuum.

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

Heart failure is a major health care problem with high mortality.

A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Humans and songbirds learn their vocalizations early in life by exposure to the vocalizations of adult conspecifics. Often, better learning outcomes are achieved with live, social, tutors than with audio-only exposure to vocalizations.

The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…

Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…