This thesis discusses the physical and chemical processes than influence the composition of forming planets.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

LIACS is a partner in RISE_SMA, an interdisciplinary, international network combining excellent scholars and practitioners to enable vigorous knowledge sharing and to develop solutions for contemporary challenges for Social Media Analytics (SMA).

In this thesis integral points on affine del Pezzo surfaces are studied.

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

The idea of citizens and public professionals collaborating to provide public services has widely spread in several countries around the globe. Co-production is often presented as the go-to solution for challenges like a legitimacy crisis of both the government and the market, and financial concerns.…

Promotor: Prof.dr. M.K. Richardson

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Promotor: Prof.dr. L.J. Slikkerveer

In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

Promotor: V. Vitelli, Co-promotor: J. Paulose

Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs

Promotor: M.T.M. Koper, Co-promotor: J.B.F. Juurlink

Promotor: D. Bouwmeester, Co-promotor: D. Kraft

Consequences for sediment stability and seston trapping

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.

Promotor: G.R. de Snoo

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

With the dramatic growth of the image data on the web, there is an increasing demand of the algorithms capable of understanding the visual information automatically.

Promotor: G.P. van Wezel

The research described in this thesis shows that hypercholesterolemia, a well-established risk factor for atherosclerosis, can impact skin lipid pool and barrier function already at young age. In the field of atherosclerosis, we showed that the small peptide Lyp-1 can be used as a targeting molecule…

Promotor: S.M. Verduyn Lunel

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

Uncertainty and noise are frequently-encountered obstacles in real-world applications of numerical optimization. The practice of optimization that deals with uncertainties and noise is commonly referred to as robust optimization.

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

Promotor: T.H. Oosterkamp

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.

Promotor: Prof.dr. M. Danhof

The explosive radiation and diversification of the advanced snakes (superfamily Colubroidea) was associated with changes in all aspects of the shared venom system. Morphological changes included the partitioning of the mixed ancestral glands into two discrete glands devoted for production of venom ormucous…

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Promotor: Christoph U. Keller, Co-promotores: Matthew A. Kenworthy, Frans Snik

This thesis discusses several questions regarding the double ramification cycle as a Chow class on the moduli space of stable n-pointed genus g curves using tools from so-called logarithmic geometry.

Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

This thesis describes the synthesis and biological evaluation of TLR2/6, TLR4, TLR7/8 and TLR9 ligands, of which the activity can be conditionally controlled.

Stellar feedback is a crucial ingredient in the evolution of galaxies.

Promotor: J.N. Kok, Co-promotor: M.S. Lew

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

Promotor: R.D. Gill, F. Taroni

Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten

Promotor: J. Schaye

Mycorrhizas are symbiotic associations between soil fungi and most plant species.

Promotor: K. Kuijken, Co-Promotor: H. Hoekstra

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Promotores: P.G.L. Klinkhamer, P.M. Brakefield, Co-Promotor: M. Bruinsma

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.