Promotor: Prof.dr. G.R. de Snoo, Co-promotor: R. Heijungs

Promotor: Prof.dr. E. Smets, M. Stech

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

Ontdek de VPR-A specialisatieopleiding Privacy- en gegevensbeschermingsrecht van Leiden law Academy, speciaal voor advocaten en juristen. Lees hier meer!

Promotores: Prof.dr. J. A. Bouwstra, Prof.dr. W. Jiskoot

This thesis investigates how galaxies form and what diversifies the evolutionary histories of galaxies.

When a star gets too close to a supermassive black hole, it is torn apart by strong tidal forces in a tidal disruption event (TDE).

As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.

Promotor: Bas Edixhoven, Promotor: Qing Liu

In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)

Studeren aan de Universiteit Leiden voor een paar uur per week? Een cursus, of een aantal vakken volgen? Er zijn diverse mogelijkheden voor geïnteresseerden om kennis op te doen bij eenvan de Leidse opleidingen.

Loopbaan en solliciteren

Studievoorlichting

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Clinical development of drugs for central nervous system (CNS) disorders has been particularly challenging and still suffers from high attrition rates.

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…

Artin L-functions associated to continuous representations of the absolute Galois group G_K of a global field K capture a lot of information about G_K as well as arithmetic properties of K.

Promotor: S.M. Verduyn Lunel

Decarbonizing the building stock is critical for realizing the climate-neutral target for the Netherlands.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer

Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)

The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.

Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)

Promotor: W. Jiskoot, Co-promotor: A. Hawe

The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

The applications of studying the early development of insects range from agriculture to material science.

LCA has become an important method to study environmental impacts of human activities. Still, there are several methodological issues in LCA that can adversely affect the results reliability.

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Promotor: Prof.dr. J.P. Abrahams, Co-Promotor: N.S. Pannu

Promotor: C.A.J. Knibbe, Co-promotores: H.P.A. van Dongen, B. van Ramshorst

Promotor: M. Danhof, Co-promotor: E.C.M. de Lange

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

Promotor: B. van de Water

Promotor: Prof.dr. B.R. Katzy, Prof.dr. H.J. van den Herik, Prof.dr. G.H. Baltes (University of Applied Sciences Konstanz)

The rapidly increasing commercial application of metallic nanoparticles within products will inevitably enhance the amount of NPs being released into soil.

Bacterial chemosensory arrays are protein assemblies that are the key structural and functional component for motile bacteria to sense their internal or environmental chemical signals.

Promotor: Prof.dr. J. den Hertog

Met het SAPPAO-project willen we de voorspelling van geplande vluchten nauwkeuriger en betrouwbaarder maken. De volledige naam van het project is ‘A Systems Approach towards Data Mining and Prediction in Airlines Operations’.

The goal of the project is the development of stream mining techniques for complex patterns such as graphs. We will try to extend the existing state-of-the-art techniques into two, orthogonal directions: on the one hand, the mining of more complex patterns in streams, such as sequential patterns and…

One of the key limitations of the direct imaging of exoplanets at small angular separations are quasi-static speckles that originate from evolving non-common path aberrations (NCPA) to which the primary adaptive optics system is inherently blind. The main focus of this thesis is the development and…

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi