1,895 zoekresultaten voor “from data to insight” in de Publieke website
- 25 Years after Hillenbrand: New Approaches to Sources Translation and Perspectives
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Decoding supplier codes of conduct with content and text as data approaches
Door de groeiende populariteit van zelfregulering door bedrijven om problemen in de leveringsketen aan te pakken, staat maatschappelijk verantwoord ondernemen in het middelpunt van de belangstelling. In dit artikel analyseren Jaroslaw Kantorowicz, Sarah Vandenbroucke en Yvonne Erkens de gedragscodes…
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BIOMOT: Motivational strength of ecosystem services and alternative ways to express the value of biodiversity
Do sustainability values play a role in motivating people to act for biodiversity in successful projects and in successful leadership action? And how could these values be incorporated in current economic valuation methods?
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Developing metabolomics for a systems biology approach to understand Parkinson's disease
Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…
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Virus-host metabolic interactions: using metabolomics to probe oxidative stress, inflammation and systemic immunity
Promotores: T. Hankemeier; R. Berger, Co-promotor: R.J. Vreeken
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska
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Crane and Wetland Conservation in African Rural Landscapes: Insights from Kenya, Uganda and Zimbabwe
This thesis focuses on the social dimensions of crane and wetland conservation in rural landscapes in Kenya, Uganda and Zimbabwe.
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A Model Membrane Approach to Elucidate the Molecular Organization in the Skin Barrier
Promotor: J. A. Bouwstra
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Semi-empirical approach to the simulation of molecule-surface reaction dynamics
Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.
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Cleared for take-off, Game-based learning to prepare airline pilots for critical situations
Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.
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Exposed to events that never happen: Genaralized unsafety and prolonged psysiological stress responses
The aims of the project are to: further clarify 'inhibition by safety'; explore and describe all possible sagety factors, with a special focus on the primary human safety source: social connectedness; reviewing prolonged stress responses without stressors.
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Global metabolomics and lipidomics approaches to probe virus-host interactions
The outbreaks of AIDS and COVID-19 showed clearly how infectious viruses can influence people’s lives. Investigating the changes in the host metabolism may provide a paradigm shift to consider immune-metabolic interactions as therapeutic targets.
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Bioorthogonal deprotection strategy to study T-cell activation and cross- presentation
Cytotoxic T-cells (CTLs) are involved in the clearance of viruses and killing of tumor cells.
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homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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ultimate leadership challenge: making critical decisions without enough data
De coronacrisis is de ultieme test voor bestuurders. Hoe houden nationale politieke leiders zich staande in hectische, dynamische tijden? Martin Lodge (London School of Economics and Political Science) en (Arjen Boin (Instituut Politieke Wetenschap Universiteit Leiden) bekijken de ervaringen opgedaan…
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Development of human skin equivalents to unravel the impaired skin barrier in atopic dermatitis skin
Promotor: J.A. Bouwstra Co-promotor: A. El Ghalbzouri
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
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ECOLE: Experience-based COmputation: Learning to optimisE
Onderzoekers van het Leiden Institute of Advanced Computer Science (LIACS) gaan een opleidingsprogramma ontwikkelen voor de volgende generatie van beginnende onderzoekers (ESR's). Gedurende een vierjarig project zullen zij worden opgeleid om industriële uitdagingen op een holistische manier te benaderen…
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
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Sports and data analytics: discovering the unknown known
The combination of data science and sports is a hot topic. In a talk during the opening of the Academic Year at the Faculty of Science, Professor Joost Kok explained what data analytics can teach us about sports.
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A culture medium based approach to optimize the stratum corneum barrier of human skin equivalents
uman skin equivalents (HSEs) are in vitro 3D-skin models that mimic many aspects of the native human skin (NHS) and can be a valuable tool.
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Politics, Culture and National Identities, 1789 to the Present (research) (MA)
De specialisatie Politics, Culture and National Identities, 1789 to the Present (research) van de Universiteit Leiden brengt je in de voorhoede van de nieuwe benadering van de manier waarop in Europa politiek en identiteit worden opgevat.
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Mining the kinematics of discs to hunt for planets in formation
Detecting planets during their formation stages is crucial for understanding the history and diversity of fully developed planetary systems like our own. However, observing young planets directly is challenging because they are often deeply embedded within their host protoplanetary discs, rich in gas…
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Linking simple molecules to grain evolution across planet-forming disks
Planets are formed in disks of gas and dust around young stars.
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assisted with stable-isotope labeling: exploring neuronal metabolism related to Parkinson’s disease
The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.
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“Special Needs by Placebo”: Programme to Advise, Normalize And Control its European Administration (PANACEA)
Hoewel veel beroepsbeoefenaren in de gezondheidszorg aangeven vaak gebruik te maken van placebo-effecten en de mechanismen ervan, is er weinig formele training over hoe om te gaan met placebo- en nocebo-effecten in de klinische praktijk. Dit project wil deze kloof tussen wetenschappelijke kennis over…
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Personalised pharmacotherapy in paediatric epilepsy : the path to rational drug and dose selection
The path to rational drug and dose selection
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Linking soil microbial community dynamics to N2O emission after bioenergy residue amendments
Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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the greening Arctic: compositional and functional shifts in response to climatic changes
Promotor: E.F. Smets Co-promotor: J. Geml
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The flexible listener: exploring zebra finch sensitivity to spectral and temporal sound features
Human vocal communication and music perception represent advanced cognitive skills, seemingly innate and universal. These faculties encompass a range of perceptual and cognitive abilities. Cross-species research sheds light on the origins of musicality by investigating whether these traits are shared…
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Responding to environmental cues: the adaptive qualities of chromatin compaction proteins
Promotor: M. Ubbink, Co-Promotor: R. T. Dame
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Sneller schaatsen dankzij data science
Veel Nederlandse schaatsers en voetballers behoren tot de absolute wereldtop. Toch kunnen ze dankzij slimme statistische analyses wellicht nóg een beetje beter worden. De Universiteit Leiden werkt er samen met Delft en Amsterdam aan.
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A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context
In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.
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EuDEco case study report (D1.3)
D1.3 describes a set of five case studies relevant in the context of the EuDEco project. Case studies are considered relevant if they are initiatives focusing on the promotion of big data and data reuse or pilots facilitating data reuse in one form or the other. The case studies were expected to allow…
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Conspiracy thinking and social media use are associated with ability to detect deepfakes
Deepfakes zijn video’s die gemanipuleerd zijn om twee personen te verwisselen. Ze kunnen moeilijk te onderscheiden zijn van de originele video’s. In onze studie laten we zien dat mensen die meer complotdenken en mensen die meer gebruikmaken van social media beter zijn in het herkennen van deepfakes.
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Genomics applications of nanopore long-read sequencing for small to large sized genomes
In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…
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Big data op kleine schaal
Mirjam van Reisen pleit voor big data, opgebouwd met lokale input in ontwikkelingslanden en geschikt voor lokaal gebruik. De nieuwe hoogleraar ‘Computing for Society’ bij de faculteit Wiskunde en Natuurwetenschappen koppelt data-science aan ontwikkelingssociologie. Oratie op 10 maart.
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Wessel Kraaij benoemd tot hoogleraar Applied Data Analytics
Wessel Kraaij is per 1 maart 2016 benoemd als hoogleraar ‘Applied Data Analytics’. Kraaij gaat grote datasets analyseren met nieuwe methoden. Met data van partijen uit verschillende data-intensieve onderzoeksdomeinen wil hij de methoden ook toetsen in de praktijk.
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Een juridische schatkist aan data
Data science biedt ongekende mogelijkheden voor juridisch onderzoek, zeggen Simone van der Hof en Bart Custers van eLaw. Maar we moeten ook de ongewenste bijwerkingen van big data - zoals etnisch profileren - in de gaten houden.
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transient reductions in the speed of sound of the inflaton in cosmological data, and other topics
Promotor: Prof.dr. A. Achucarro
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Van Vonno, Achieving Party Unity: A Sequential Approach to Why MPs Act in Concert (dissertatie)
Cynthia van Vonno, politicoloog aan de Universiteit Leiden, verklaart in haar proefschrift waarom individuele parlementariers meestemmen met hun fractie.
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Two-photon luminescence of gold nanorods: applications to single-particle tracking and spectroscopy
Gold nanorods are biocompatible nanoparticles that present an excellent two-photon signal that can be used to get high spatial resolution inside living cells. Gold nanorods are photostable and therefore can be followed inside cells for long time, with possible applications as trackers in live cells.
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The mixed Ax-Lindemann theorem and its applications to the Zilber-Pink conjecture
Promotores: Prof.dr. S.J. Edixhoven, Prof.dr. E. Ullmo (University Paris-Sud)
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Radio-interview met Barend Mons over FAIR Data
Wetenschappers moeten gemakkelijker gebruik kunnen maken van elkaars data, vindt een groep onderzoekers van verschillende universiteiten. Daarvoor ontwikkelden ze de FAIR-principes. BNR Nieuwsradio sprak erover met initiatiefnemer Barend Mons, hoogleraar Biosemantiek aan het Leids Universitair Medisch…
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Door data te integreren kunnen we onze kennis vergroten
In wetenschappelijk onderzoek worden iedere dag enorme hoeveelheden data geproduceerd. Die zouden we nog veel meer kunnen benutten dan we op dit moment doen, zegt Katy Wolstencroft, assistent-professor in (bio)informatica. Maar dan moeten we de data wel beter beheren en integreren.
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Masterstudenten Data Science presenteren oplossingen aan Rijk en Tweede Kamer
Op 1 november 2019 presenteerden internationale masterstudenten Data Science van de Universiteit Leiden de uitwerking van hun dataconcepten aan hoge functionarissen van de Tweede Kamer en het Rijks I-Ecosysteem. Met de presentatie rondden ze dit deel van de mastercursus Data Science succesvol af.