1,063 zoekresultaten voor “been en get a” in de Publieke website
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The effects of burying beetle social behaviours on interspecific interactions
This ecological community has long been known to affect host biology, and their diverse roles have been further clarified in recent years following numerous studies of animal:microbiota interactions in diverse systems.
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Neutrinos From the Milky Way
Promotor: Prof.dr. M. de Jong
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Impacts of the use of Natural Resources and Products
Development of an aggregated impact indicator to measure decoupling.
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The Regional Network on the Synergy between the Convention on Biological Diversity and the UN Convention to Combat Desertification
Description of The Regional Network on the Synergy between the Convention on Biological Diversity and the UN Convention to Combat Desertification.
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Rechtsgeleerdheid: eLaw
eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?
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A cross-sectional study of early language abilities in children with sex chromosome trisomy (XXY, XXX, XYY) aged 1–6 years
Een goede taalontwikkeling is van belang voor de cognitieve en sociale ontwikkeling, om te kunnen communiceren en om te kunnen leren. Als de taalontwikkeling niet verloopt zoals verwacht, kan dit allerlei consequenties hebben. Kinderen met een extra X of Y chromosoom hebben een verhoogd risico op problemen…
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‘Pensioengeletterdheid in Nederland is laag’
Uit een studie van Marike Knoef, Jim Been en Marijke van Putten is gebleken dat Nederlanders weinig weten over hun pensioen. Voor Marike Knoef, hoogleraar empirische micro-economie, komt dit niet als een verrassing: 'Pensioengeletterdheid is laag, zeker onder jongeren.'
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The Makings of a Terrorist: Continuity and Change Across Left-, Right- and Jihadist Extremists and Terrorists in Europe and North-America, 1960s-Present
In dit artikel doen Bart Schuurman en Sarah Louise Carthy onderzoek naar de oorzaken van terrorisme door verschillen en overeenkomsten tussen links-, rechts- en jihadistische extremisten te vergelijken.
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Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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Lights in a sea of darkness: constraining the nature and properties of dark matter using the stellar kinematics in the centres of ultra-faint
Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.
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Can large carnivores like tigers survive in multiple use forests? A study in the buffer zone of Panna Tiger Reserve, India.
Welke factoren (mens-dimensie en carnivoor-gerelateerd) zijn bepalend voor de menselijke tolerantie ten opzichte van grote carnivoren en voor de overlevingskansen van grote carnivoren in bossen met meervoudig gebruik?
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Schouwburgstraat Community Garden
In the Schouwburgstraat, LUGO is currently redesigning the back-garden in order to increase biodiversity and make it a more beautiful space. Throughout October 2023 until March 2024, we will be making changes to the garden with our team of volunteers.
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Indicators for "decoupling"
Indicators to measure progress in de-linking economic growth and environmental pressure.
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Inhibitor Selectivity: Profiling and Prediction
Less than 1 in 10 drug candidates that enter phase 1 clinical trials actually gets approved for human use.
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Internship information
An important part of the SCS specialisation is the internship period. Students will get the opportunity to get to know the field and to apply what they have learned during the courses.
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Synthetic peptides, nucleic acids and molecular probes to study ADP-Ribosylation
This thesis presents the first synthetic peptides ADP-ribosylated on serine, threonine, tyrosine, arginine and cysteine.
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Pesticides Atlas overhauled in line with European Framework Directive on Water
The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).
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Conference "Thomas a Kempis" (Nijmegen)
The Titus Brandsma Institute and Radboud University Nijmegen organize an international conference on Thursday 19 and Friday 20 August 2021: Thomas a Kempis, his Works and their Reception.
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Inferno Worlds
A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.
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Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Bacterial glycomimetics: synthesis and applications
This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.
- Thesis Lab: "The Source Course" (3 ECTS)
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What's mine is yours and what yours is mine: Teacher communities as a means to increase adoption of Open Educational Resources in curricula?
Er zijn wereldwijd vele open (leer)materialen beschikbaar, maar deze worden nog niet of zeer beperkt gebruikt in het onderwijs.
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‘Lab on a chip’ gaat gezondheidszorg ingrijpend veranderen
Snelle en goedkope chips die extreem kleine hoeveelheden vloeistof (microfluïden) analyseren vormen de kern van gepersonaliseerde gezondheidszorg. Maar het ‘laboratorium op een chip’ is nog niet effectief genoeg. Dr. Paul Vulto en zijn onderzoeksteam ontwikkelden een techniek die het gebruik van microfluïdische…
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Morphogenesis and protein production in Aspergillus niger
Promotores: C.A.M.J.J. van den Hondel, V. Meyer, Co-promotor: A.F.J. Ram
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Publicaties
Publicaties die verschijnen in het kader van het onderzoeksproject Zelfredzaamheid en sociale bescherming over de levenscyclus.
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Carbon4PUR | Turning industrial waste gases (mixed CO/CO2 streams) into intermediates for polyurethane plastics for rigid foams/building insulation
What would be the environmental performance of the Carbon4PUR technology at industrial scale in the future?
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Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
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Over het Dual PhD Centre
Het Dual PhD Centre bestaat om een bijzondere groep promovendi aan de Universiteit Leiden extra ondersteuning te bieden: de duale promovendi.
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Coiled-coil biomaterials for biological applications
This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.
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Force sensing and transmission in human induced pluripotent stem-cell-derived pericytes
Pericytes, the mural cells of blood microvessels, are important regulators of vascular morphogenesis and function that have been postulated to mechanically control microvascular diameter through as yet unknown mechanisms.
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Towards superconducting spintronics with RuO2 and CrO2 nanowires
CrO2, a half-metal ferromagnet, has shown great promise for superconducting spintronics applications for nearly two decades.
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Postmaterialism and Socioeconomic Status Impact in the Chilean Voting Behavior
This paper describes the development process of voting behavior in Chile; particularly the relationship between the class voting theory and the theory of cultural post-materialist vote is investigated. This research deals with Chile as a case study, a developing country with a relatively stable democracy…
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Spectroscopic characterization of exoplanets: From LOUPE to SINFONI
Over the past years it has been discovered that the population of extra-solar planets is large and diverse.
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Pyrrole-based photoswitchable anion receptors
The main goal of this thesis is to achieve advanced control of binding properties in bis-pyrrolic and macrocyclic pyrrolic receptors by light.
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Total Synthesis of Alginate and Zwitterionic Sp1 Oligosaccharides
The work in this thesis has been focused on two subjects. The first is the assembly of alginate oligosaccharides and the generation of building blocks for the enzymatic synthesis of alginate, and the second is the total synthesis of large fragments of the zwitterionic SP1 polysaccharide.
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The development of molecular tools for investigating NAD+ metabolism and signalling
Nicotinamide adenine dinucleotide (NAD+) is the substrate used for the introduction of the ubiquitous and highly dynamic PTM in which either one or multiple adenosine diphosphate ribose (ADPr) moieties are covalently attached to a nucleophilic side chain of an specific amino acid in the target protein…
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Explorations of Water Oxidation Catalysis in Explicit Solvent
In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.
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Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
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Substances from Cradle to Grave
Materials balances have been used in the recent past for the analysis of substance oriented environmental problems and the formulation of measures for environmental policy. In this study an integrated tool, based on the materials balance principle, has been developed for the analysis of both environmental…
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Dynamics of the Oort Cloud and Formation of Interstellar Comets Santiago Torres Rodriguez
The solar system was formed approximately 4.56 billion years ago. Despite the numerous theories that have been developed over the years, the formation and evolution of the solar system still remain unclear.
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Lespakketten ‘Universe in a Box’ gaan de hele wereld over
EU Universe Awareness (EU-UNAWE), een educatief sterrenkundeproject van de Leidse Sterrewacht, heeft gloednieuw lesmateriaal ontwikkeld: Universe in a Box. Het toegankelijke lespakket is ontworpen om de moeilijke en soms abstracte concepten van sterrenkunde uit te leggen aan jonge kinderen van 4 tot…
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Kickstart het heelal - Crowdfunding voor Universe in a Box
Het project Universe Awareness (UNAWE) van de Universiteit Leiden organiseert een Kickstarter crowdfunding campagne om de lespakketten van 'Universe in a Box', een lespakket voor sterrenkunde, zoveel mogelijk te kunnen verspreiden onder kansarme gemeenschappen over de hele wereld. De campagne werd gelanceerd…