Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Met de NMR faciliteit doen we onderzoek naar de synthese van paramagnetische moleculen om kennis te vergaren over de structuur en dynamiek van eiwitten. Deze kennis kan dienen als basis voor een medicijn dat zich hecht aan een eiwit of voor de ontwikkeling van vaccins. Medicijnontwikkeling is één van…

Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

Op 13 januari 2022 verdedigde Pie Habimana het proefschrift 'Harmful Tax Competition in the East African Community'. Het promotieonderzoek is begeleid door prof.dr. H. Vording en prof.dr. S.C.W. Douma (UvA).

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Promotor: K.E. Schalm, Co-promotor: S.S. Lee

In het hoger onderwijs zijn open leermaterialen beschikbaar die iedereen mag gebruiken, maar ze worden niet zo veel gebruikt.

Supramolecular polymers are class of materials that are formed by non-covalent interactions such as hydrogen bonding, π-π interactions, electrostatic interactions and the hydrophobic effect.

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Promotor: A. Kros

Promotor: S.M. Verduyn Lunel, Co-promotor: O.W. van Gaans

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

Promotores: Prof.dr. A.G.G.M. Tielens, Prof.dr. L. Kaper (UvA)

Waar gaan de quantummechanica, de relativiteitstheorie en de zwaartekracht elkaar vinden? Wat is het missende stukje? Of is er een compleet nieuwe theorie die alle vormen van materie elegant beschrijft?

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

With the help of quantum mechanics, digital quantum hardware may be able to tackle some of the problems that are too difficult for ordinary computers. But despite these expectations and the ongoing effort of the research community, reliable quantum computers are not yet realized in a lab setting.

Promotor: Prof.dr. M.L. van Hecke, Co-Promotor: V. Vitelli

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Promotor: H.V.J. Linnartz

This thesis addresses the chemical processes that determine the compositions of giant planet atmospheres.

This dissertation studies the Asymptotics of Bayesian nonparametric inference for Gaussian linear models.

Algoritmen ontwerpen is een van de onderzoeksonderwerpen waar Leiden sterk in is. Want supercomputers moeten niet alleen gebouwd worden, maar ook geprogrammeerd. Wetenschappers van internationale faam doen hier onderzoek naar.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.

In condensed matter systems electron-electron interactions, negligible in everyday metals, can dramatically alter the electronic behavior of the system. Examples of such altered behavior include high-temperature superconductivity and modulation of the electron density.

Stars like the sun are born in large molecular clouds existing from gas and dust. During the formation process, the chemical composition of the material can be altered drastically by the changing physical conditions.

The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.

Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.

Overall dispersion in LCA as result of inherent uncertainties, spread and unrepresentativeness.

What physics controls the properties of quantum matter, such as how electrons flow inside high-temperature superconductors? This question has captivated the physics community and industry for decades, in part due to the great technological potential such materials have, but also because they have resisted…

Visualizing the internal structure is a crucial step in acquiring knowledge about the origin, state, and composition of cultural heritage artifacts. Among the most powerful techniques for exposing the interior of cultural heritage objects is computed tomography (CT), a technique that computationally…

The application of nanomaterials in industrial processes and consumer products provides many societal benefits, but can also lead to the release of nanomaterials into the environment. The work in this dissertation aims to provide insights into the potential environmental impacts that may follow from…

Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…

Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten de masteropleiding. De Universiteit Leiden stimuleert studenten om na hun bacheloropleiding door te gaan met de masteropleiding.

Wat is het effect op het milieu van het 2016-verbod op gratis plastic tasjes? Industrieel ecoloog Stefano Cucurachi heeft een subsidie ontvangen van €75.000 van het LUF-SVM Projectsubsidie Fonds* om deze vraag te beantwoorden.

De Tatiana Afanassjewa-lezingenreeks is een reeks publiekslezingen op woensdagavonden waarvoor iedereen met natuurkundige belangstelling van harte is uitgenodigd.

Promotores: Prof.dr. G.A. Persoon & Prof. dr. H.H. de Iongh

Promotor: Prof.dr. M. Schilthuizen

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Can we provide the Dutch government with an integrative framework, wherein the various policies can be placed and the need for further measures can be identified?

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.