892 zoekresultaten voor “high both dettje” in de Publieke website
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LIBC Onderzoeksfaciliteiten
Faciliteiten waar LIBC leden gebruik van kunnen maken (in het Engels):
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Interactions of nutrients and pesticides and their effects on aquatic macrofauna
Can we distinguish the effects of pesticides from other abiotic and biotic factors that occur in the field? And how do these factors interact with pesticides?
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Multi-Biomarker Pharmacokinetic-Pharmacodynamic Relationships of Central Nervous Systems Active Dopaminergic Drugs
Discovery and development of Central Nervous System (CNS) drugs is hampered by high attrition rates.
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Laboratory studies of Water Ice in Space
Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.
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Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development
Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.
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The electrochemical reduction of dioxygen and hydrogen peroxide by molecular copper catalysts
The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…
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The early stress response of jasmonic acid in cell suspension cultures of Catharanthus roseus
In order to gain a better insight into the basis of the rapid jasmonic acid (JA)-mediated stress response, an integrated approach using a targeted high-resolution mass spectrometry-based (HRMS) platform, was conducted to monitor the metabolism of JA using the model system of cell suspension cultures…
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Genetic and environmental factors determining heterogeneity in preservation stress resistance of Aspergillus niger conidia
Fungal food spoilage often starts with a contamination with spores. Experimental data strongly indicate the existence of subpopulations of spores with different levels of resistance to preservation methods.
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Development of a Kidney-on-a-Chip Model for Compound Screening and Transport Studies
Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…
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The use of computational toxicology in hazard assessment of engineered nanomaterials
Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…
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Multi-objective mixed-integer evolutionary algorithms for building spatial design
Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.
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The spin evolution of accreting and radio pulsars in binary systems
Pulsars were first discovered in 1967 and since then the population has grown and expanded over several wavelengths.
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BodoArXiv - RI OPAC
A couple of years ago Guy Geltner and Daniel Lord Smail founded BodoArxiv. It provides an open, non-profit repository for papers in medieval studies at different stages of gestation. Anyone can access and download any item on BodoArXiv freely and immediately (see: https://bodoarxiv.wordpress.com/) .…
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Jean Monnet Chair of Moritz Jesse
Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.
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PhD candidate - biodiversity & society: the Dutch home as a multispecies space
The Faculty of Science is looking for a:PhD candidate - biodiversity & society: the Dutch home as a multispecies spaceVacancy number: 14709 Project descriptionA substantial part of biodiversity is situated within private spheres of homes and this is also the biodiversity that most intimately affects…
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2 PhD Candidates, Reinforcement Learning for Sustainable Energy
The Faculty of Science and the Leiden Institute of Advanced Computer Science (LIACS) are looking for:2 PhD Candidates, Reinforcement Learning for Sustainable Energy These positions are embedded in the Reinforcement Learning Lab for Sustainable Energy, a cooperation between Leiden University and an industrial…
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PhD Candidate Law and Digital Technologies (0.8-1.0 fte)
PhD Candidate Law and Digital Technologies (0.8-1.0 fte)Vacancy Number: 14834Elaw, the Center for Law and Digital Technologies at Leiden University, is looking for a PhD candidate in Law and Digital Technologies. This role is combined with the role of program assistant for our advanced master program…
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2 Assistant Professors in Generative AI and Human-centered AI
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Spin transport and superconductivity in half-metallic nanowires and junctions
The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.
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Resource allocation in networks via coalitional games
Promotor: F. Arbab, R. De Nicola, Co-Promotor: M. Tribastone
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Towards thermo- and superlubricity on the macroscopic scale: from nanostructure to graphene and graphite lubrication
The thesis describes experimental steps towards reduction of friction on the macroscopic scale by scenarios of thermo- and superlubricity well-known on the nanoscale.
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Assistant Professor Methodology & Statistics
Assistant Professor Methodology & StatisticsThe Faculty of Social and Behavioural Sciences, Institute of Psychology, the Methodology and Statistics unit has a vacancy for a position as anAssistant Professor Methodology & Statistics (1 position, 1.0 FTE)Preferred starting date: August, 2024 Key…
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Systemen en beveiliging
Onderzoekers van LIACS werken aan het bedenken van de computers van morgen die de ruggengraat zullen vormen van de Cloud en Edge computing paradigma’s en ‘the Internet of Things’. In dit verband zijn we betrokken bij onderzoek en ontwikkeling van high performance computing systemen, embedded & real-time…
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PhD position within the project 'Libraries as Links in Learning: Making the Meaning of Manuscripts'
Leiden University Centre for the Arts in Society (LUCAS) invites applications for aPhD position within the project ‘Libraries as Links in Learning: Making the Meaning of Manuscripts’ (1.0 fte, 4 years) The PhD candidate will be working within the multi-member research project ‘Libraries as Links in…
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PhD candidate, Compliance by Design: Technical Challenges of EU AI Act Requirements and Their Ethica
The Faculty of Science and the Leiden Institute of Advanced Computer Science (LIACS) are looking for a:PhD candidate, Compliance by Design: Technical Challenges of EU AI Act Requirements and Their Ethical Implications AI Compliance by Design: Technical Challenges of EU AI Act's Requirements and Their…
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Postdoctoral Researcher in the project "Contagious Digitalities: Information, Inoculation, Immunity"
Geesteswetenschappen, Centre for the Arts in Society
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An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality
Op 18 september 2019 verdedigde Huw Llewellyn zijn proefschrift 'An Institutional Perspective on the United Nations Criminal Tribunals: Governance, Independence and Impartiality'. Het promotieonderzoek is begeleid door promotoren prof.dr. N.M. Blokker en prof.dr. L.J. van den Herik.
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Searching by Learning: Exploring Artificial General Intelligence on Small Board Games by Deep Reinforcement Learning
In deep reinforcement learning, searching and learning techniques are two important components. They can be used independently and in combination to deal with different problems in AI, and have achieved impressive results in game playing and robotics. These results have inspired research into artificial…
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Positioning of current Environmental tools & an outlook to the future
Review of new technical decisionsupport systems in the environmental field, and application in water management decission processes.
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Towards improved drug action : target binding kinetics and functional efficacy at the mGlu2 receptor
During the course of drug discovery translational steps are made.
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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Control of Western flower thrips through jasmonate-triggered plant immunity
We showed that constitutive and inducible chemical and morphological defenses against Western flower thrips differ between tomato and chrysanthemum plants.
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Emerging approaches to study cell-cell interactions
The aim of this thesis is to study cell-cell interactions and the development of an assay to explore and quantify the exchange of membrane compounds.
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From intracluster medium dynamics to particle acceleration
The intracluster medium (ICM) is a hot, tenuous and X-ray emitting gas that pervades galaxy clusters.
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ALGANT
Fundamental research in the ALgebra, Geometry And Number Theory
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Basis reduction for layered lattices
Promotor: H.W. Lenstra
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Dynamics of a β-lactamase
BlaC is the β-lactamase of Mycobacterium tuberculosis. We show that it can recover from inhibition by clavulanic acid and that phosphate helps it do so.
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Extended Essays
Leiden University’s Academic Challenge
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Links between cohomology and arithmetic
Promotor: S.J. Edixhoven
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On the geometry of demixing: A study of lipid phase separation on curved surfaces
Like a mixture of oil and water, lipid membranes separate into two liquid phases.
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Towards a greater understanding of the presence, fate and ecological effects of microplastics in the freshwater environment
This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.
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Identification of novel targets in prostate cancer progression
Promotor: B. van de Water, Co-promotor: E.H.J. Danen
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Spectroscopy of two-field inflation
This thesis is about cosmological inflation and its relation to observations.
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Information Diffusion Analysis in Online Social Networks based on Deep Representation Learning
With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.
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Electroextraction approaches for preconcentration of metabolites
In this thesis, we developed new ways to use a technique called electroextraction (EE) to extract charged molecules from one liquid into another using an electric field.
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PhD Access to Medicine
Do you want to be part of a dynamic international team working on cross-disciplinary legal research to improve children’s access to medicine in Africa?The Child Law & Health Law Department of the Institute for Private Law at Leiden Law School invite applications for a Doctorate in Law (PhD):The…
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De kwaliteit van bestuur, maatschappelijk vertrouwen of partijvoorkeuren? Verschillen in politieke besluitvorming over COVID-19 maatregelen in
Verschillen in politieke besluitvorming over COVID-19 maatregelen in Europa
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Carbon4PUR | Turning industrial waste gases (mixed CO/CO2 streams) into intermediates for polyurethane plastics for rigid foams/building insulation
What would be the environmental performance of the Carbon4PUR technology at industrial scale in the future?
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To explore the drug space smarter: Artificial intelligence in drug design for G protein-coupled receptors
Over several decades, a variety of computational methods for drug discovery have been proposed and applied in practice. With the accumulation of data and the development of machine learning methods, computational drug design methods have gradually shifted to a new paradigm, i.e. deep learning methods…