This book aims to be a point of reflection and debate for journalists, academics and students to recognize a fundamental task in the duty of the communications professional, which is to influence through their daily work and their routines in order to achieve a more inclusive and plural society, through…

Cryptanalist Marc Stevens van het Centrum Wiskunde & Informatica (CWI) in Amsterdam, bekend van zijn 'kraak' van de MD5 hash-functie voor https-beveiliging in 2008, heeft deze week het recente Flame-virus geanalyseerd. Hij ontdekte dat voor deze spy malware een compleet nieuwe, tot nu toe onbekende…

In dit artikel onderzochten Annemiek de Looze en Eefje Cuppen empirisch of en hoe sociaal conflict leidt tot institutionele verandering.

Studying the impact of urbanisation on the respiratory health of past Dutch populations (1200-1850 CE).

What is the population size and social structure in time and space? What is the lion diet and food preference in time and space? What is the home range (MCP and Kernel) and movement in time and space? What are human – lion conflict and responses of lions to traditional herding in time and space? What…

CREEA is a FP7 project on compiling and refining environmental and economic accounts. The project runs from April 2011 to March 2014.

Writing an operational guide to the ISO standards for LCA and related sub-projects.

Na 25 jaar is het deze december eindelijk zo ver: de lancering van de lang verwachte James Webb ruimtetelescoop. Leidse astronomen kijken vol spanning mee: niet alleen waren zij betrokken bij de bouw van belangrijke instrumenten aan boord, de telescoop zal ook vele nieuwe geheimen van het heelal onthullen,…

Na 25 jaar is het deze december eindelijk zo ver: de lancering van de lang verwachte James Webb ruimtetelescoop. Leidse astronomen kijken vol spanning mee: niet alleen waren zij betrokken bij de bouw van belangrijke instrumenten aan boord, de telescoop zal ook vele nieuwe geheimen van het heelal onthullen,…

How can we quantify the density of species within a community through environmental DNA concentrations?

Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

Wat zijn de gevolgen van maatschappelijke trends zoals vergrijzing, individualisering en internationalisering voor regelgeving en instituties op het terrein van sociale zekerheid, pensioenen en de arbeidsmarkt?

A critical look at the impact assessment modelling of metals in Life Cycle Impact Assessment and improvement options.

How do nanoparticles bioaccumulate and biodistribute in organisms?

Accumulation of metals in economy and environment and its associated risks, within the Netherlands and the EU.

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Promotor: A. Achúcarro, Co-promotor: A. Boyarsky

Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

In this thesis we investigated the ability of two-photon multifocal microscopy for single-molecule microscopy in live cells and organisms.

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

Software development is a complex process. It is important that software products become stable and maintainable assets.

Promotor: Prof.dr. S.F. Portegies Zwart

Promotor: P.G.L. Klinkhamer, Co-Promotores: K. Vrieling, P.P.J. Mulder

This thesis is largely an experimental study on the formation of solid-state simple and complex organic molecules in the H2O-rich and CO-rich ice phases of dense interstellar clouds and dark cores.

Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn

Solar energy harnessed by plants and algae has great potential to be converted into biofuels for future generations.

Promotor: W. Jaffe, Co-promotor: K. Meisenheimer

Low-mass main-sequence stars like our Sun are continuous sources of outflowing hot magnetised plasma. In the case of the Sun, this is known as the solar wind, whereas for other stars they are called stellar winds.

This thesis describes the implementation and on-sky demonstration of high-resolution integral-field spectroscopy for extreme adaptive optics systems that are used to find and characterize exoplanets.

Fundamental research in the ALgebra, Geometry And Number Theory

Promotor: Prof.dr. W.J.G.M. Peijnenburg

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Promotor: G.A. van der Marel, Co-promotor: D.C. Codée

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Promotores: Prof.dr. G.F.A Kersten, Prof dr. J.A. Bouwstra

Promotor: G.R. de Snoo

Diacylglycerol lipases (DAGLα and DAGLβ) are responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the brain and peripheral tissues. Selective DAGLβ inhibitors have been proposed as a potential treatment for inflammatory diseases with reduced potential for central…

What is the current relevance of the ethics of counterterrorism and what is the added value of ethics support within the practice of counterterrorism?

Promotores: Wim Jiskoot; Ferry Ossendorp

Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).

Promotor: Prof.dr. C.W.J. Beenakker

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Cardiovascular disease is the leading cause of death worldwide.

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Plant diversity is essential for us and our planet as it sustains the stability of our ecosystems, provides vital materials and food to us and supports many ecosystem services.

Promotor: J.N. Kok, Co-promotor: M.S. Lew

Empirical Legal Studies in Leiden focust op het bouwen van een interdisciplinaire gemeenschap van rechtsgeleerden en sociale wetenschappers die samen juridische vraagstukken onderzoeken op het snijpunt van recht en gedrag, waarbij diverse soorten methoden worden gebruikt.