441 zoekresultaten voor “synthesis biology” in de Publieke website
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Sustainable Chemistry and Biotechnology
If mankind wants to survive into the 22nd century, we will need to change the way we live drastically. The human impact on our planet is everywhere, we are changing the atmosphere, the oceans and the land, leading to global warming, climate change, loss of biodiversity and pervasive pollution. There…
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Human Evolution
This multidisciplinary minor provides students with knowledge on how and why humans became the way they are. The minor focuses on the evolution of the species Homo sapiens from other hominin lineages and animal ancestors, and on the various factors shaping this process. Not only is human evolution of…
- Van Darwin tot DNA
- Onderzoeksfaciliteiten
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De Ethiopische wolf: gerespecteerd én bedreigd door lokale veehouders
De zeldzame Ethiopische wolf komt steeds vaker in aanvaring met lokale veehouders. Promovendus Girma Eshete zocht naar manieren om het elegante beest te redden van de ondergang. Promotie op 5 september.
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Wil Tamis
Wiskunde en Natuurwetenschappen
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Esther van der Ent
Wiskunde en Natuurwetenschappen
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Hermen Overkleeft
Wiskunde en Natuurwetenschappen
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Systems biology as a compass to understand cancer-immune interactions in humans
Promotie
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Duurzame toekomst
Hoe kunnen we onze maatschappij zo inrichten dat de wereld leefbaar blijft voor onszelf en al het andere leven om ons heen? Aan dat vraagstuk werken Leidse wetenschappers samen vanuit allerlei disciplines, van biologie tot datawetenschap en van milieueconomie tot archeologie.
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PhD position in 'Effects of Pollution at the Ecosystem Level'
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)
- PhD: Targeting electron transport chain in Listeria monocytogenes for novel antibiotic development
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Onderzoek
Steden, Voedsel, Water, Biodiversiteit, Bronnen en Energie: dit zijn de belangrijkste onderzoeksthema’s voor het CML. Ons doel is altijd om wereldwijd voorop te lopen in ons vakgebied. En echte impact te hebben met onze onderzoeksprogramma’s.
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Volatile compounds from Actinobacteria as mediators of microbial interactions
Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.
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PNEC-pro
PNEC-pro is a user-friendly screening tool for professionals dealing with the assessment of surface water quality. The tool calculates local, watertype specific no-effect concentrations (PNEC) of copper, lead, nickel and zinc based on biotic ligand models (BLMs).
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Analysis of the angucycline biosynthetic gene cluster in Streptomyces sp. QL37 and implications for lugdunomycin production
Streptomyces bacteria are a valuable source of natural products, many of which are used in the clinic or in biotechnology.
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Optical properties of DNA-hosted silver clusters
Promotor: D. Bouwmeester, Co-promotor: D. Kraft
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Coiled-coils on lipid membranes: a new perspective on membrane fusion
Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros
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Analysis and Stochastics
The research of the Applied Mathematics cluster is concerned with such diverse topics as dynamical systems, representation theory, differential equations and pattern recognition.
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Towards Optical Detection of a Single Electron
Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.
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Biophysical characterization of membrane protein-small molecule interactions
Promotor: Prof.dr. M. Ubbink
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Orchid mycorrhizal interactions: evolutionary trajectories and ecological variations
The mycorrhizal symbiosis is among the most widespread species interactions on Earth. This thesis focuses on orchid mycorrhiza, a unique mycorrhizal type that has caught scientists’ attention for centuries.
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Random walks and the contact process
Promotores: W. Th. F. den Hollander, M.O. Heydenreich
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Dynamics of coupled quantum systems
Thermodynamics is one of the founding scientific pillars that has helped us better understand heat engines, biology, ecosystems, and even black holes. While it fundamentally describes large systems by examining the bulk behavior of their constituents, it is anchored in the statistical equivalence of…
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eV-TEM: Transmission Electron Microscopy with few-eV Electrons
Electron microscopy has become an extremely important techniquein a wide variety of elds.
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Education
The specialisation Science Communication and Society (SCS) concerns science communication in a broad sense. The program focuses on the link between science and society and covers knowledge and skills in the field of science communication.
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Sparsity-Based Algorithms for Inverse Problems
Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…
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Mechanical and genetics basis of cellularization and serosal window closure in Tribolium castaneum
The applications of studying the early development of insects range from agriculture to material science.
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Systems pharmacology of the amyloid cascade
According to the amyloid cascade hypothesis, accumulation of beta-amyloid (Aβ) peptides initiates the pathological cascade in Alzheimer's disease (AD).
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Toll-like receptor signaling in the innate immune system of zebrafish larvae
Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez
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Vervolgopleidingen
Na het afronden van de bacheloropleiding volgen verreweg de meeste studenten de masteropleiding. De Universiteit Leiden stimuleert studenten om na hun bacheloropleiding door te gaan met de masteropleiding.
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Programmastructuur
De masteropleiding Health, Ageing and Society leidt haar studenten op tot academische professionals op het gebied van gezondheid, ouderen en samenleving. Studenten voelen zich na afronding van de opleiding betrokken bij de maatschappij en zijn in staat om een bijdrage te leveren aan oplossingen voor…
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Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
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Nobelprijs Scheikunde voor 3D-beelden van moleculen
De Nobelprijs voor Scheikunde 2017 is uitgereikt aan Jacques Dubochet, Richard Henderson en Joachim Frank, voor hun ontwikkeling van de cryo-elektronenmicroscopie. Met deze techniek kunnen biomoleculen in 3D in beeld gebracht worden, legt hoogleraar Ultrastructuurbiologie Ariane Briegel uit.
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Unfolding the principles of genome folding and dynamics in bacteria
Remus Dame
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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Lespakket Antibiotica Gezocht!
Zelf met leerlingen aan de slag in een zoektocht naar antibiotica? Met het practicum Antibiotica Gezocht! gaan bovenbouw havo- en vwo-leerlingen tijdens de biologieles op zoek naar (nieuwe) antibioticum-producerende bacteriën.
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A time-space translation mechanism for patterning the vertebrate anteroposterior axis
My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.
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Metabolomic characterization of plant exudates and their correlation with plant defense systems
Plant exudates appeared long time ago in the history line of life in the early Devonian. They are typical saps produced by specialized cells.
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Afrikaanse leeuw twee ondersoorten
De traditionele scheiding van leeuwen in een Afrikaanse en een Aziatische ondersoort is onterecht, zegt bioloog Laura Bertola. In Afrika leven twee ondersoorten. Promotie 18 maart.
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Klein maar niet zo fijn?
In hoeverre hopen nanodeeltjes zich op in planten en dieren, en welke eigenschappen van de deeltjes spelen hierbij een rol? Willie Peijnenburg, hoogleraar Milieutoxicologie en biodiversiteit kreeg een Marie-Curie beurs toegekend om onderzoek te doen naar de milieueffecten van nanodeeltjes.
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Meest diverse koraalriffen niet altijd best beschermd
Over de hele wereld staan koraalriffen onder druk. Zarinah Waheed onderzocht de riffen in Maleisië en komt tot de conclusie dat de bescherming van koraalriffen beter kan. Promotie op 22 november.
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Does knowledge of environmental performance change farmer's behaviour?
Does knowledge of environmental performance change farmer's behaviour?
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Milieuchemisch analist en technisch labmanager (1.0 fte)
Wiskunde en Natuurwetenschappen, Centrum voor Milieuwetenschappen Leiden (CML)
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Develop a methodology for assessing the effective dose of nanomaterials for environmental risk assessment purposes
How to make a quantitative assessment of the relative contribution to toxicity of ions and particles? Is the toxicity of nanoparticles related to their size or shape? Which physicochemical property of nanoparticles is an appropriate dose metric of nanoparticles?
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Competition on bird feeeders between introduced Ring-necked parakeets and native bird species in the Netherlands
Does the presence of Ring-necked parakeets negatively influence feeding and feeding behaviour of native bird species on artificial bird feeders and if so, what are possible solutions?
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Nieuwe technieken voor medicijn tegen tuberculose
Wereldwijd krijgen jaarlijks ongeveer 9 miljoen mensen tuberculose. Onderzoek naar nieuwe medicijnen tegen deze ziekte heeft een flinke impuls gekregen door efficiëntere technieken en nieuwe inzichten in hoe de tuberculosebacterie werkt.