2,646 zoekresultaten voor “state cell technology” in de Publieke website
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Max FernkornFaculteit der Wiskunde en Natuurwetenschappen
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Benjamin TakFaculteit der Wiskunde en Natuurwetenschappen
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Rafaella BuzatuFaculteit der Wiskunde en Natuurwetenschappen
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Christian SchröterFaculteit der Wiskunde en Natuurwetenschappen
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Andreea Iosif
Faculteit der Wiskunde en Natuurwetenschappen
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Eliane ZügerFaculteit der Wiskunde en Natuurwetenschappen
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Yubin GuoFaculteit der Wiskunde en Natuurwetenschappen
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Micha DrukkerFaculteit der Wiskunde en Natuurwetenschappen
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Jingchao WuFaculteit der Wiskunde en Natuurwetenschappen
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Joey ZuijderveltFaculteit der Wiskunde en Natuurwetenschappen
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Daan VlemmingsFaculteit der Wiskunde en Natuurwetenschappen
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Nina SchultenFaculteit der Wiskunde en Natuurwetenschappen
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Ruben de VriesFaculteit der Wiskunde en Natuurwetenschappen
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Yuting WangFaculteit der Wiskunde en Natuurwetenschappen
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Ferdinand TeichertFaculteit der Wiskunde en Natuurwetenschappen
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Cecile Herbermann -
Vincent KoemanFaculteit der Wiskunde en Natuurwetenschappen
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Luuk Reinalda
Faculteit der Wiskunde en Natuurwetenschappen
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Capturing dynamics with noisy quantum computers
Quantum computing represents a fundamentally new computational paradigm, capable of addressing problems that are intractable for classical computers.
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Extracellular Matrix Mechanics in the Regulation of the early steps of the Metastatic Cascade
Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.
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Cristina del Real nam deel aan presentatie van Office of Science and Technology voor Spaanse regering
Cristina del Real, universitair docent Cyber Crisis bij het Institute Security and Global Affairs, nam deel aan de presentatie van het Office of Science and Technology (OficinaC) voor het Spaanse Congres van Afgevaardigden (het Spaanse parlement). Ze is een expert in cyber security, een van de vier…
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On transport properties of Majorana fermions in superconductors: free & interacting
Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.
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Paul van TrigtFaculteit der Geesteswetenschappen
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Huub de GrootFaculteit der Wiskunde en Natuurwetenschappen
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Liberalisering en privatisering in het bestuursrecht bij de Raad van State
Vrijdag 28 oktober 2016 vond op de Raad van State het symposium ‘De gevolgen van privatisering en liberalisering voor de rechtsbescherming door de bestuursrechter’ plaats. De Afdeling Staats- en bestuursrecht van de Universiteit Leiden en de Raad van State organiseerden gezamenlijk dit symposium, ter…
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Raad van State zet streep door schietbanen Defensie
De discussie over de sluiting van illegale schietbanen van Defensie, als gevolg van de stikstofwetgeving is ingewikkeld en omvat diverse juridische aspecten. Armin Cuyvers, hoogleraar Europeesrecht, bespreekt de zaak in BNR-Nieuwsradio.
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Summer Course: Europeanisation of Administrative Law in the Member States
Van 26 t/m 30 juni 2017 organiseert de afdeling Staats- en Bestuursrecht van de Universiteit Leiden een zomercursus over de Europeanisering van het nationaal bestuursrecht in de lidstaten van de Europese Unie.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Physics implications of shape on biological function
Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.
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Technology and the State: Enlightenment Language Machines, Then and Now
Lezing, Research Seminar Medieval and Early Modern History
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Flow and Vasculature in Organ-on-a-Chip systems
Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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The heart of oxygenic photosynthesis illuminated
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Orientational Order and Confinement in Biological Tissues
This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Development of a healthy and diseased artery-on-a-chip
Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Over het programma
In 2020 zijn de stimuleringsprogramma's van de Universiteit Leiden gestart, met als één van de programma's regeneratieve geneeskunde.
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Shijie WeiFaculteit der Wiskunde en Natuurwetenschappen
- Laboratory for Ceramics Studies
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Software
Image-Pro Plus, ImageJ, Cell Profiler, R, Knime en NIS-elements
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Mutation-Driven Modulation of GPCR Pharmacology: Insights from Adenosine and Serotonin Receptors
This thesis seeks to investigate how cancer-associated mutations affect the pharmacological properties of selected GPCRs—primarily A2AAR and 5-HT2CR—through a combination of ligand binding assays, signaling readouts, kinetic profiling, and cellular functional assays.
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Composition and function of integrin adhesions
Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.
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Deep Learning Solutions for Domain-Specific Image Segmentation
Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.
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Spatio-temporal aspects of antigen cross-presentation in dendritic cells: with click-to-release chemistry
The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Metabolomics study of blood vessels-on-chip model
Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.