2,151 zoekresultaten voor “state cell technology” in de Publieke website
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in Nieuwsuur over de gevolgen van de PAS-uitspraak van de Raad van State
Rogier Kegge, universitair docent bestuursrecht en omgevingsrecht, vertelt in Nieuwsuur over de verstrekkende gevolgen van de uitspraak van de Afdeling Bestuursrechtspraak van de Raad van State van 29 mei 2019 (ECLI:NL:RVS:2019:1603) over het Programma Aanpak Stikstof.
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RNA splicing in breast cancer progression
In this thesis, we aimed to better understand the underlying mechanisms involved in TNBC progression and metastasis formation and discover new targets to reduce breast cancer related deaths.
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Max Fernkorn -
Jingchao Wu -
Nina Schulten -
Yuting Wang -
Andreea Iosif
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Micha Drukker -
Eliane Züger -
Rafaella Buzatu -
Yubin Guo -
Ferdinand Teichert -
Ruben de Vries -
Benjamin Tak -
Joey Zuijdervelt -
Daan Vlemmings -
Capturing dynamics with noisy quantum computers
Quantum computing represents a fundamentally new computational paradigm, capable of addressing problems that are intractable for classical computers.
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Extracellular Matrix Mechanics in the Regulation of the early steps of the Metastatic Cascade
Metastasis is responsible for over 90% of cancer-related deaths and arises from the ability of a small subset of tumor cells to detach from the primary tumor, overcome multiple biochemical and mechanical barriers, disseminate through the body, and colonize distant organs.
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Vincent Koeman -
On transport properties of Majorana fermions in superconductors: free & interacting
Majorana fermions in superconductors are the subgap quasiparticle excitations that are their own antiparticles.
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Liberalisering en privatisering in het bestuursrecht bij de Raad van State
Vrijdag 28 oktober 2016 vond op de Raad van State het symposium ‘De gevolgen van privatisering en liberalisering voor de rechtsbescherming door de bestuursrechter’ plaats. De Afdeling Staats- en bestuursrecht van de Universiteit Leiden en de Raad van State organiseerden gezamenlijk dit symposium, ter…
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Raad van State zet streep door schietbanen Defensie
De discussie over de sluiting van illegale schietbanen van Defensie, als gevolg van de stikstofwetgeving is ingewikkeld en omvat diverse juridische aspecten. Armin Cuyvers, hoogleraar Europeesrecht, bespreekt de zaak in BNR-Nieuwsradio.
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Summer Course: Europeanisation of Administrative Law in the Member States
Van 26 t/m 30 juni 2017 organiseert de afdeling Staats- en Bestuursrecht van de Universiteit Leiden een zomercursus over de Europeanisering van het nationaal bestuursrecht in de lidstaten van de Europese Unie.
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Luuk Reinalda
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Paul van TrigtFaculteit der Geesteswetenschappen
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Huub de Groot -
Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Sensing Transport
Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.
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Physics implications of shape on biological function
Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.
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Flow and Vasculature in Organ-on-a-Chip systems
Drug development critically depends on preclinical models that mimic human physiology, yet traditional two-dimensional cultures and animal models often lack predictive power.
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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The heart of oxygenic photosynthesis illuminated
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
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Orientational Order and Confinement in Biological Tissues
This thesis investigates how cell shape and collective behavior influence the dynamics and structure of biological tissues, which are crucial for understanding processes like embryonic development, tissue regeneration, and metastasis.
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Growth-induced self-organization in bacterial colonies
Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.
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Development of a healthy and diseased artery-on-a-chip
Cardiovascular diseases are a leading cause of death worldwide, and better models are urgently needed for disease progression studies and drug development.
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High throughput microscopy of mechanism-based reporters in druginduced liver injury
Promotor: B. van de Water
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Over het programma
In 2020 zijn de stimuleringsprogramma's van de Universiteit Leiden gestart, met als één van de programma's regeneratieve geneeskunde.
- Laboratory for Ceramics Studies
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Software
Image-Pro Plus, ImageJ, Cell Profiler, R, Knime en NIS-elements
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Mutation-Driven Modulation of GPCR Pharmacology: Insights from Adenosine and Serotonin Receptors
This thesis seeks to investigate how cancer-associated mutations affect the pharmacological properties of selected GPCRs—primarily A2AAR and 5-HT2CR—through a combination of ligand binding assays, signaling readouts, kinetic profiling, and cellular functional assays.
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Shijie Wei -
Composition and function of integrin adhesions
Integrins play an essential role in multicellular life by connecting cells to the extracellular matrix.
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Deep Learning Solutions for Domain-Specific Image Segmentation
Image segmentation is a fundamental task in computer vision, with applications ranging from medical diagnostics to archaeological research.
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Spatio-temporal aspects of antigen cross-presentation in dendritic cells: with click-to-release chemistry
The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.
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Analysis of sub-visible particles in complex injectable formulations
Promotors: W. Jiskoot; G.J. Witkamp, Co-promotor: M.R. Nejadnik
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Metabolomics study of blood vessels-on-chip model
Endothelial dysfunction and microvascular diseases are key drivers of cardiovascular disease, the world's leading cause of death.
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More is alive: emergent multi-scale order & collective flows in tissues
The overarching goal of this thesis is to set the foundations, but also make the first essential steps towards establishing a comprehensive, mesoscopic, hydrodynamic theory of epithelial tissues. The stage is set by an exhaustive study of topological defects in passive p-atic liquid crystals, singularities…
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Resolving the Dynamic Structure of Chlorosomes in Green Sulfur Bacteria by MAS NMR
Understanding how nature captures and transfers solar energy is essential both for elucidating biological photosynthesis and for guiding the design of artificial light-harvesting systems.
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Modeling and Targeting Tissue Dynamics in Fibrosis and Cancer
Drug development is hampered by the limited predictive value of conventional 2D culture systems, which fail to recapitulate the complexity of the disease microenvironment and contribute to high clinical attrition rates.