2,877 zoekresultaten voor “from new 26 disinformation” in de Publieke website
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Twee Leidse MOOCs bij de beste volgens New York Magazine
‘Heritage under Threat’ en ‘The Rooseveltian Century’ horen volgens New York Magazine tot de beste 21 MOOCs voor een breed publiek.
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Exploring the chemical space of post-translationally modified peptides in Streptomyces with machine learning
The ongoing increase in antimicrobial resistance combined with the low discovery of novel antibiotics is a serious threat to our health care.
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Tommy van Avermaete
Universitaire Bibliotheken Leiden
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Natural and non-natural factors influencing Alzheimer´s Aβ
Promotor: Prof.dr. J.P. Abrahams
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Ruthenium- and cobalt-based artificial metalloenzymes for photocatalytic water oxidation in artificial photosynthesis
Producing green energy has become the main goal in our society in the search of reducing or eliminating the carbon emission from fossil fuels.
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High-contrast imaging polarimetry of exoplanets and circumstellar disks
Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.
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Governance and Data Science Group
The extensive use of electronic communication channels and other devices has opened new possibilities for collecting data on human behavior. This information is sometimes openly accessible, but largely part of administrative registration systems that are not open to the broader public. The data provides…
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Antithrombotic therapy in the Netherlands- New insights from nationwide data
Promotie
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Algant Consortium bijeenkomsten in Leiden 23-26 februari 2013
Op zaterdag 23 en zondag 24 februari vinden de jaarlijkse ‘Algant doctorate candidates and academics’ bijeenkomsten plaats. Het Algant consortium bestaat uit 8 universiteiten op 4 continenten en biedt een tweejarige mastertrack aan en een joint PhD programma in de Algebra, Meetkunde en Numerieke Wis…
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Novel analytical approaches to characterize particles in biopharmaceuticals
Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).
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Jean Monnet Chair of Moritz Jesse
Moritz Jesse has been awarded a Jean Monnet Chair by the European Commission. In his MIND-EU Project he will focus on a coherent way to teach Migration, Integration, and Non-Discrimination at Leiden Law School at bachelor and master level.
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Chemical tools to study the cannabinoid receptor type 2
The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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Bayesian learning: challenges, limitations and pragmatics
This dissertation is about Bayesian learning from data. How can humans and computers learn from data?
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Distant star formation in the faint radio sky
One of the key quests in astronomy is to study the growth and evolution of galaxies across cosmic time. Radio observations provide a powerful means of studying the formation of stars and subsequent buildup of distant galaxies, in a way that is unbiased by the presence of dust.
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Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
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The quantification of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
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Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'
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Cancer chess: molecular insights into PARP inhibitor resistance
The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…
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Children’s Rights in International Commercial Surrogacy
Op 26 juni 2018 verdedigde Claire Achmad haar proefschrift 'Children’s Rights in International Commercial Surrogacy: Exploring the Challenges from a Child Rights, Public International Law Perspective'. Het promotieonderzoek is begeleid door promotor prof. mr. drs. M.R. Bruning.
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The Sand Motor - Building with Nature to optimise coastal protection and other ecosystem services
How can mega sand nourishments, such as the Sand Motor, be designed and managed for optimal ecosystem services provision ?
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Flow: A study of electron transport through networks of interconnected nanoparticles
This thesis describes a study from both a theoreticaL and an experimental point of view.
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The power of one qubit in quantum simulation algorithms
Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…
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Giant galactic outflows and shocks in the Cosmic Web
The radio sky harbours both galactic and extragalactic sources of arcminute- to degree-scale emission of various physical origins. To discover extragalactic diffuse emission in the Cosmic Web beyond galaxy clusters, one must image low–surface brightness structures amidst a sea of brighter compact fore-…
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Network flow algorithms for discrete tomography
Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele
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Twintig jaar jihadismebestrijding in West-Europa: van de schok van 9/11 tot "jihadismemoeheid"
Dit artikel beschrijft een overzicht van twee decennia na 9/11 in West-Europa. De auteurs kijken naar de ontwikkeling van de dreiging, het contra-terrorismebeleid en de impact hiervan op de samenleving.
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Bioorthogonal Antigens as Tool for Investigation of Antigen Processing and Presentation
In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…
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A computational study of structural and excitonic properties of chlorosomes
The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…
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Gravitational waves through the cosmic web
The first direct detection of gravitational waves opened the possibility of mapping the Universe via this new and independent messenger.
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Assessing the link between television consumption and the attitudes toward people living with HIV/AIDS in Chile
We analyse the link between media consumption and the attitudes toward people living with HIV/AIDS in Chile. We used data from a sample of 1000 people, obtained in the 2011 wave of the World Values Survey (WVS). We use a logistic binary regression model by maximum likelihood. Our results suggest that…
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Modern Drug Discovery
How are new drugs developed? This question is central to the Minor Modern Drug Discovery (MDD), which covers the entire trajectory from disease to drug molecule and vice versa. The various research groups involved offer a complementary and interdisciplinary perspective by connecting the diverse subjects…
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Radio galaxies near the epoch of reionisation
This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.
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Rechtsgeleerdheid: eLaw
eLaw onderzoekt de rol van het recht in de informatiemaatschappij: hoe kan het recht bijdragen aan een goede werking van informatie- en communicatietechnologie, en het gebruik ervan door burgers, bedrijven en overheden?
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LURIS presenteert boek ‘Focus on the Appliance of Science from Leiden’
Leiden University Research & Innovation Services (LURIS), de afdeling van de Universiteit Leiden en het LUMC die de valorisatie van het wetenschappelijk onderzoek stimuleert en in goede banen leidt, presenteert op 28 oktober het boek Focus on the Appliance of Science from Leiden. Dat laat vanuit diverse…
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Leids onderzoek naar corona-afval belandt in New York Times
Mondkapjes en plastic handschoenen moeten ons beschermen tegen corona, maar vormen een steeds groter probleem voor het milieu. In een special van de New York Times vertellen de Leidse bioloog Liselotte Rambonnet en alumnus Auke-Florian Hiemstra over hun onderzoek hiernaar, en de speciale website die…
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Painting with starlight : optical techniques for the high-contrast imaging of exoplanets
This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.
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Pesticides Atlas overhauled in line with European Framework Directive on Water
The Dutch atlas with pesticides concentrations in surface waters have been overhauled. This new, free accessible, website is in line with the European Framework Directive on Water (In Dutch: KRW).
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Research Seminar Series
For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent
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Science Communication & Society
The research group Science Communication and Society aims to understand how science communication works to improve the interaction between science and society. Central themes are ‘Bridging the gap between experts and the general public’ and ‘Evaluating Science Communication’.
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Chaotic dynamics in N-body systems
Promotor: Prof.dr. S.F. Portegies Zwart
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Filter-based reconstruction methods for tomography
Promotor: K.J. Batenburg
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Taxonomy, systematics, and biogeography of Ficus subsection Urostigma (Moraceae)
Promotor: Prof.dr. P.C. van Welzen
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Novel approaches for direct exoplanet imaging: theory, simulations and experiments
The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.
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Arguably augmented reality : relationships between the virtual and the real
This thesis is about augmented reality (AR). AR is commonly considered a technology that integrates virtual images into a user’s view of the real world.
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Low-Energy Electron Microscopy on Two-Dimensional Systems: Growth, Potentiometry and Band Structure Mapping
Promotor: Prof.dr. J.M. van Ruitenbeek, Prof.dr. R.M. Tromp
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Attacks on hash functions and applications
Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger
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Applications of paramagnetic NMR spectroscopy for protein research
The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.
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The colours of the extreme universe
This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.
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A pharmacognostic study of Vernonia guineensis Benth. (Asteraceae): bioactivity, safety, and phytochemical analysis
Promotor: Prof.dr. R. Verpoorte, Co-Promotor: Dr. Young Hae Choi
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Spectral imaging and tomographic reconstruction methods for industrial applications
Radiography is an important technique to inspect objects, with applications in airports and hospitals. X-ray imaging is also essential in industry, for instance in food safety checks for the presence of foreign objects.