523 zoekresultaten voor “some problems” in de Publieke website
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Scalability and uncertainty of Gaussian processes
The main theme of this thesis is the theoretical study of Gaussian processes as a tool in Bayesian nonparametric statistics.
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On cluster algebras and topological string theory
My PhD research is devoted to studies of the conjectural cluster-algebraic symmetry in the theory of topological string, which is the simplest, however already non-trivial sector in the theory of string.
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Play by the rules? : coordination of EU sustainable development policies and the importance of the politico-legal context
There is an increasing amount of attention on EU and its Member States contributions to implementation of two landmark agreements: the Paris Climate Agreement and the UN Agenda 2030 with Sustainable Development Goals (SDGs). Absent from the current literature is an analysis of the political effect of…
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Logarithmic Hochschild homology and cohomology
In this thesis, we explore a Hochschild homology and cohomology-like notion for logarithmic schemes.
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The power of one qubit in quantum simulation algorithms
Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…
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Arakelov inequalities and semistable families of curves uniformized by the unit ball
The main object of study in this thesis is an Arakelov inequalitywhich bounds the degree of an invertible subsheaf of the direct image ofthe pluricanonical relative sheaf of a semistable family of curves.
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Gas physics of simulated galaxy clusters
The largest structures in the Universe are clusters of galaxies. Each can contain hundreds to thousands of galaxies.
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Off the wall: characterisation and exploitation of a cell wall deficient life style in filamentous actinomycetes
Almost all bacteria are enveloped by a cell wall that provides cellular protection.
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Far from home: the science exploitation of the fastest Milky Way stars
The Sun and all the stars in the night sky reside in the Milky Way galaxy. In the at-rest reference frame of the Galaxy, typical stars travel with velocities of about 100-200 kilometres per second.
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On Multifield Inflation, Adiabaticity and the Speed of Sound of the Curvature Perturbations
Promotor: A. Achúcarro, Co-Promotor: G.A. Palma
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Control of early plant development by light quality
This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants.
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Translational Symmetry Breaking in Holographic Strange Metals
In this thesis, we have used numerical approaches to study the effects of translational symmetry breaking on strange metallic systems as realised by the holographic duality.
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Spectroscopy of two-field inflation
This thesis is about cosmological inflation and its relation to observations.
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Measures and Matching for Number Systems
This thesis provides explicit expressions for the density functions of absolutely continuous invariant measures for general families of interval maps, that include random maps and infinite measure transformations, not necessarily number systems.
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Next generation bacitracin: reimagining a classic antibiotic
Given the accelerating appearance of antimicrobial resistance, there is an urgent need for more fundamental research into novel antibiotic strategies. The work in this thesis helps to address this global problem by developing new antibiotic compounds, inspired by the antibacterial mechanisms of the…
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Towards a greater understanding of the presence, fate and ecological effects of microplastics in the freshwater environment
This thesis combines field and laboratory studies to address some of the most pressing questions in the field of microplastic research.
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Studying through the summer?
Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…
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Design, synthesis, and evaluation of antigenic peptide conjugates containing Toll-like receptor agonists
This thesis describes the design, synthesis, and immunological evaluation of varying (neo)antigenic peptide conjugates containing either a TLR2 or a TLR7 agonist.
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Wetenschappelijke publicaties
Een lijst met wetenschappelijke publicaties samengesteld door het team van het TRIXY Expertisecentrum.
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Galois representations of elliptic curves and abelian entanglements
Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Universite Bordeaux I)
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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Onderzoeksgroep Geweld en Geweldpreventie (Violence and Violence Prevention)
Bij de Onderzoeksgroep Geweld en Geweldpreventie (Violence and Violence Prevention) wordt onderzoek gedaan naar de complexiteit van hedendaags geweld, de uiteenlopende verschijningsvormen ervan en strategieën voor preventie.
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Probing Gravity at Cosmic Scales
The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Algorithm selection and configuration for Noisy Intermediate Scale Quantum methods for industrial applications
Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.
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Quantum local asymptotic normality and other questions of quantum statistics
Promotor: R. Gill, Co-promotor: P. Massart
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Pharmaceutical Aspects of Subvisible Particles in Protein Formulations
Promotor: W. Jiskoot, Co-promotor: A. Hawe
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De negatieve gevolgen van pesten
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Approach to Markov Operators on Spaces of Measures by means of equicontinuity
The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.
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Mining Sensor Data from Complex Systems
Promotor: J.N. Kok, Co-Promotor: A.J. Knobbe
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ALL-IN meta-analysis
Science is typically a patchwork of research contributions without much coordination. Especially in clinical trials, the follow-up studies that we do fail to be the most promising.
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Sterile neutrinos in the early Universe
Promotor: A. Achúcarro, Co-promotor: A. Boyarsky
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Magnetism and magnetization dynamics in thin film ferromagnets
Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek
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Interactive scalable condensation of reverse engineered UML class diagrams for software comprehension
Promotores: Prof.dr. J.N. Kok, Prof.dr. M.R.V. Chaudron (Chalmers Univ., Sweden)
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Novel regulators of prostate cancer stem cells and tumor aggressiveness
Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm
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Matchmaking for open innovation: perspectives on multi-sided markets
Promotores: Prof.dr. B.R. Katzy, Prof.dr. K. Sailer (Munich University)
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Massively collaborative machine learning
Promotor: J. N. Kok, Co-promotor: A. J. Knobbe
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Microengineered Human Blood Vessels For Next Generation Drug Discovery
Heart failure is a major health care problem with high mortality.
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Modelling the dynamics of the innovation process: a data-driven agent-based approach
Promotor: Prof.dr. B.R. Katzy
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Structure-reactivity relationships in glycosylation chemistry
In a typical glycosylation reaction, a donor is activated to form a (variety of) electrophilic species which can react with a nucleophilic acceptor, following a reaction mechanism having both SN1 and SN2 character.
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Sterrewacht Leiden
Sterrewacht Leiden is het sterrenkundig instituut van de Faculteit der Wiskunde en Natuurwetenschappen van de Universiteit Leiden.
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creatIef, Creatiever, creaTiefst? Onderzoek naar het belang en de werking van creativiteitstraining bij Bachelor ICT-studenten
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.
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Pattern mining for label ranking
Promotor: J.N. Kok, Co-promotor: C.M. Soares, A.J. Knobbe
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Small changes for long term impact: optimization of structure kinetic properties: a case of CCR2 antagonists
Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman
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Automated machine learning for dynamic energy management using time-series data
Time-series forecasting through modelling sequences of temporally dependent observations has many industrial and scientific applications. While machine learning models have been widely used to create time-series forecasting models, creating efficient and performant time-series forecasting models is…
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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Selectivity and competition between the anodic evolution of oxygen and chlorine
Sustainable energy from wind and solar is most readily available near the sea.
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Unraveling temporal processes using probabilistic graphical models
Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.
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Benchmarking Discrete Optimization Heuristics
This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.