Promotor: S.J. Edixhoven

Promotores: Bas Edixhoven, Jean-Benoit Bost, Co-promotor: Robin de Jong

The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.

Promotor: R. Tijdeman, Co-promotor: C. Kraaikamp

Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer

The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.

Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit

Hoe kun je het getal pi benaderen met tandenstokers? Hoe rekenden de Babyloniërs? Zijn er wel normale getallen? Hoeveel is een triljoen eigenlijk? Hoe bereken je de ware liefde? Wat is het vermoeden van Kepler? En wat is binair rekenen eigenlijk?

De Microscopy Unit huisvest, onderhoudt en coördineert vrijwel alle microscopieapparatuur van het IBL. De beschikbare apparatuur varieert van conventionele licht- en fluorescentiemicroscopen tot confocale laser- en elektronenmicroscopen. Er is bovendien apparatuur beschikbaar voor histologie, met inbegrip…

Dit project beoogt de ontwikkeling van geavanceerde data-analysemethoden voor monitoring en het vergroten van ons inzicht in de dynamiek van de biodiversiteit in natuurgebieden zoals de Oostvaardersplassen.

The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Het Mathematisch Instituut is een van de acht instituten van de Faculteit der Wiskunde en Natuurwetenschappen. Het instituut opereert als een eenheid gedefinieerd door de activiteiten van de medewerkers.

Wiskundemeisje, wetenschapsjournalist en alumna Ionica Smeets zat gisteravond drie uur lang aan tafel bij Zomergasten-presentator Wilfried de Jong.

Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.

This thesis consists of three chapters, the first two of which concern division points of elements of the multiplicative group of a number field.

Promotor: A.W. van der Vaart

Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu

We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.

Promotores: H.W. Lenstra, B. Erez, Co-promotor: L. Taelman

We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.

Promotor: W.Th.F. den Hollander

Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

De 21e eeuw is getuige van een revolutie in ons begrip van rationale punten op oppervlakken en hoger-dimensionale variëteiten, en het is binnen dit vakgebied dat dit project zich bevindt.

Promotor: Prof.dr. P. Stevenhagen, Co-Promotor: J.H. Evertse

Promotor: Robert Tijdeman, Co-promotor: Cornelis Kraaikamp

n this thesis we study curves. In the first half, we study moduli spaces of curves and Gromov-Witten invariants, certain kinds of curves counts. We employ logarithmic geometry for this.

In this thesis we examine certain phenomena in symplectic topology which are related to the theory of isolated singularities.

Een uitgebreid overzicht van het onderzoek van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website

Een uitgebreid overzicht van het onderwijs van de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website

Een uitgebreid overzicht van software en data beschikbaar gesteld door de afdeling Environmental Biology is beschikbaar op de Engelse versie van de CML-website

Over de hele wereld staan koraalriffen onder druk. Zarinah Waheed onderzocht de riffen in Maleisië en komt tot de conclusie dat de bescherming van koraalriffen beter kan. Promotie op 22 november.

While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Promotor: Prof.dr. G.R. de Snoo

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Large carnivore population is globally declining as a result of the fragmentation of habitat, large prey depletion and retaliatory killing by pastoralists.

Microscopic insight on lipid-based nanomedicine in vivo remains limited to the perception of the knowledge that could be obtained: if we interpret only what we see, then we only believe to know. Although believing to know encapsulates an undefined amount of uncertainty in the exploration of lipid-based…

This thesis describes the genetic and prokaryotic diversity of giant barrel sponges.

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…

The research described in this thesis focused on the use of bioorthogonal antigens to investigate immunological processes in antigen presenting cells. Bioorthogonal antigens are antigenic proteins produced through recombinant expression in a methionine auxotrophic E. coli strain.

Promotor: Richard D. Gill

Wij voeren multidisciplinair onderzoek uit op het niveau van moleculen, cellen en organismen binnen de dierkunde. Ons doel is om fundamentele kennis te vergroten over gezondheid en ziekte.

The aim of the research described in this thesis was to use structure-based design to optimise multiple properties of aryl sulfoxide monoacylglycerol lipase inhibitors as anti-inflammatory analgesics.