2,343 zoekresultaten voor “mathematisch biology” in de Publieke website
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High-throughput simulation studies of angiogenesis - Reverse engineering the role of tip cells and pericytes in vascular development
Promotor: Prof.dr. R.M.H. Merks
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Computational modeling of angiogenesis : from matrix invasion to lumen formation
Promotor: Roeland M.H. Merks
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Activity-based protein profiling of glucosidases, fucosidases and glucuronidases
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea
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David Mattias VersluisWiskunde en Natuurwetenschappen
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Algebra, Geometry and Number Theory
Het onderzoek binnen het Algebra, Geometry and Number Theory programma varieert van fundamentele wiskundige theorie tot algoritmes en toepassingen.
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Prediction Sets via Parametric and Nonparametric Bayes: with Applications in Pharmaceutical Industry
This thesis consists of five chapters on how to construct prediction sets for different types of data and models in a parametric or nonparametric Bayesian paradigm.
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Approaching equilibrium in a dynamic network
This dissertation presents four separate chapters, all striving towards the same goal: to understand dynamic phenomena occurring in dynamic networks and to explore the emergence of equilibrium in a broad sense.
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Bad reduction of Hilbert modular varieties with parahoric level structure
Promotor: S.J. Edixhoven, A. Iovita
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Noisy Patterns: Bridging the gap between stochastics and dynamics
In this thesis, we study travelling waves in stochastic reaction-diffusion equations. We extend techniques from the deterministic theory for travelling waves to apply to the stochastic version, which allows us to compute the stochastic wave speed and shape, and draw conclusions on the stability of the…
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General Mathematics Colloquium
Wetenschappelijke staf van het Mathematisch Instituut organiseert meerdere keren per jaar het General Mathematics Colloquium.
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Theses
Het scriptiearchief dat te vinden was op de website van het Mathematisch Instituut wordt momenteel overgezet naar het Leids Repositorium. Binnenkort kunnen daar de theses vanaf 2008 worden geraadpleegd.
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Wiskunde en Natuurwetenschappen
Binnen de Faculteit der Wiskunde en Natuurwetenschappen zijn 8 instituten:
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Isogeny graphs, modular polynomials, and applications
This thesis has three main parts. The first part gives an algorithm to compute Hilbert modular polynomials for ordinary abelian varieties with maximal real multiplication. Hilbert modular polynomials of a given level b give a way of finding all of the abelian varieties that are b-isogeneous to any given…
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Statistical Science
Het onderzoeksprogramma Statistical Science houdt zich bezig met de analyse en interpretatie van grote hoeveelheden data, de kwantificering van onzekerheid met behulp van kansmodellen en de ontwikkeling en benchmarking van algoritmen en methoden gericht op dataonderzoek.
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Scaling Limits in Algebra, Geometry, and Probability
Central Limit Theorem associated to a particular case of ergodic total automorphisms. Finally, Chapter 6 proves that the isoperiodic foliation is connected for a meromorphic differential with three poles on a torus.
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Shtuka cohomology and special values of Goss L-functions
Assuming everywhere good reduction we generalize the class number formula of Taelman to Drinfeld modules over arbitrary coefficient rings.
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Jacqueline Meulman en Johan Memelink benoemd tot lid KHMW
De Koninklijke Hollandsche Maatschappij der Wetenschappen verwelkomt in 2015 23 nieuwe directeuren, 25 nieuwe leden en 4 nieuwe buitenlandse leden.
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Inverse electron demand Diels-Alder pyridazine elimination: synthetic tools for chemical immunology
The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…
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Microscopy Unit
De Microscopy Unit huisvest, onderhoudt en coördineert vrijwel alle microscopieapparatuur van het IBL. De beschikbare apparatuur varieert van conventionele licht- en fluorescentiemicroscopen tot confocale laser- en elektronenmicroscopen. Er is bovendien apparatuur beschikbaar voor histologie, met inbegrip…
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Een nieuw tijdperk voor natuurbehoud met behulp van hyperspectrale en lidargegevens; de Oostvaardersplassen als casestudie
Dit project beoogt de ontwikkeling van geavanceerde data-analysemethoden voor monitoring en het vergroten van ons inzicht in de dynamiek van de biodiversiteit in natuurgebieden zoals de Oostvaardersplassen.
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Modular forms of weight one over finite fields
Promotor: S.J. Edixhoven
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Deterministic equation solving over finite fields
Promotor: H.W. Lenstra
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Constructing elliptic curves of prescribed order
Promotor: Peter Stevenhagen
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Tautological differential forms on moduli spaces of curves
In this thesis we study the moduli space of genus g curves, and the differential forms that occur naturally on this moduli space.
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Discrete tomography with two directions
Promotores: R. Tijdeman, K.J. Batenburg
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Empirical Bayes applications in biomedical high-dimensional prediction
The thesis introduces three methods for high-dimensional prediction problems in the biomedical field. The methods make use of empirical and variational Bayes in the estimation.
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Arakelov invariants of Belyi curves
Promotores: Bas Edixhoven, Jean-Benoit Bost, Co-promotor: Robin de Jong
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Ik was altijd heel slecht in wiskunde
Hoe kun je het getal pi benaderen met tandenstokers? Hoe rekenden de Babyloniërs? Zijn er wel normale getallen? Hoeveel is een triljoen eigenlijk? Hoe bereken je de ware liefde? Wat is het vermoeden van Kepler? En wat is binair rekenen eigenlijk?
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Pulses in singularly perturbed reaction-diffusion systems
Promotor: Arjen Doelman, Co-promotor: Vivi Rottschäfer
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Knowledge extraction in the quantum random-oracle model
The aim of this thesis is to present novel techniques for proving cryptographic schemes secure against quantum adversaries. Most results are within the context of an idealized model called the ‘quantum random-oracle model’.
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Induced substitutions
Promotor: R. Tijdeman, Co-promotor: C. Kraaikamp
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Mersenne primes and class field theory
Promotor: H.W. Lenstra, Jr., Co-promotor: B. de Smit
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Strategy Dynamics
In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.
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Over ons
Het Mathematisch Instituut is een van de acht instituten van de Faculteit der Wiskunde en Natuurwetenschappen. Het instituut opereert als een eenheid gedefinieerd door de activiteiten van de medewerkers.
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Ionica Smeets in Zomergasten (VPRO)
Wiskundemeisje, wetenschapsjournalist en alumna Ionica Smeets zat gisteravond drie uur lang aan tafel bij Zomergasten-presentator Wilfried de Jong.
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Jing SunWiskunde en Natuurwetenschappen
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Topological aspects of rational points on K3 surfaces
Promotor: P. Stevenhagen, Co-promotor: R.M. van Luijk
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Positive representations on ordered Banach spaces
Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu
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Néron models in high dimension: nodal curves, Jacobians and tame base change
We describe certain birational modifications of nodal relative curves over a regular base of arbitrary dimension.
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Division points in arithmetic
This thesis consists of three chapters, the first two of which concern division points of elements of the multiplicative group of a number field.
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E-values for anytime-valid inference with exponential families
Traditional hypothesis testing requires researchers to set a fixed sample size in advance. After collecting data, the test determines whether to reject the null hypothesis.
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Decompositions in algebra
We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.
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On the Galois closure of commutative algebras
Promotores: H.W. Lenstra, B. Erez, Co-promotor: L. Taelman
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Topics in mathematical and applied statistics
Promotor: A.W. van der Vaart
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Random walks in dynamic random environments
Promotor: W.Th.F. den Hollander
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Interactions of symplectic topology with singularity theory
In this thesis we examine certain phenomena in symplectic topology which are related to the theory of isolated singularities.
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Rational Points: New Dimensions
De 21e eeuw is getuige van een revolutie in ons begrip van rationale punten op oppervlakken en hoger-dimensionale variëteiten, en het is binnen dit vakgebied dat dit project zich bevindt.
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Symmetric Diophantine approximation over function fields
Promotor: Prof.dr. P. Stevenhagen, Co-Promotor: J.H. Evertse
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Enumerative arithmetic
This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.