Promotor: Bas Edixhoven, Promotor: Qing Liu

Does knowledge of environmental performance change farmer's behaviour?

This thesis contains results on the arithmetic and geometry of del Pezzo surfaces of degree 1.In Chapter 1 we give the necessary background, assuming the reader is familiar with algebraic geometry.

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This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

Didactiek

Promotor: S.J. Edixhoven, L.D.J. Taelman

The aim of this thesis is to explore the use of Bioorthogonal Antigens to study the cross-presentation pathway.

This thesis consists of three chapters. Each chapter is on a different subject. However, all three chapters address issues that arise in counting arithmetically interesting objects.

Kennis van moslimsamenlevingen is onmisbaar om in een geglobaliseerde wereld te kunnen functioneren en om onze eigen Nederlandse maatschappij goed te begrijpen. In Leiden verdiepen onderzoekers zich in de talen, cultuur, religie, rechtssystemen en geschiedenis van moslimsamenlevingen en zetten daarmee…

This thesis consists of three chapters, the first two of which concern division points of elements of the multiplicative group of a number field.

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

Promotor: J. Zaanen

The first steps are made in personalised cancer vaccination strategies, which aim to induce a more specific immune response with fewer side effects. The activation of cytotoxic T cells is crucial for an effective immune response.

Participatie onderzoeksthema's

Op 1 juni 2022 verdedigde Tom Herrenberg het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. P.B. Cliteur en prof.dr. B.R. Rijpkema.

Hoe beïnvloedt de #MeToo-beweging, en specifiek de #ChurchToo-beweging, de structuren en praktijken binnen transnationale Pinksterkerken? En welke patronen van seksueel geweld en intimidatie kunnen worden geïdentificeerd in zowel Nigeria als Los Angeles?

Geesteswetenschappen, Institute for Area Studies

Promotor: J.S. Kaastra Co-promotor: E. Constantini

The thesis addresses the long-term dynamical evolution of hierarchical multiple systems.

A substance flow analysis, covering about 99 % of the flows of chlorinated substances in the Netherlands.

Lees waar je als student van de Universiteit Leiden terecht kunt voor steun als je die nodig hebt en welke afspraken er gelden voor sociale veiligheid in de online leeromgeving.

Samen met wetenschappers van over de hele wereld streeft de ENIGMA-Anxiety Werkgroep ernaar om meer inzicht te krijgen in de neurobiologische karakteristieken van angststoornissen.

We show that Kirchhoff ’s law of conservation holds for non-commutative graph flows if and only if the graph is planar. We generalize the theory of (Euclidean) lattices to infinite dimension and consider the ring of algebraic integers as such a lattice.

Promotor: S.J. Edixhoven Co-promotor: L. van Geemen, P. Parent

In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

In het academisch jaar 2023-2024 biedt het interdisciplinaire onderzoeksprogramma Sociale Veerkracht en Veiligheid vier vakken aan voor studenten die beginnen met het derde jaar van hun bachelor. Deze vakken zijn te volgen binnen de ruimte voor keuzevakken. Je kunt de vakken afzonderlijk als keuzevak…

Simulatieproject EAGLE heeft de 2022 Group Achievement Award van de Royal Astronomical Society gewonnen. EAGLE is een grote verzameling aan simulaties over het ontstaan van sterrenstelsels. De grootste simulatie bevat wel 6.8 miljard deeltjes en kostte maanden om te berekenen op ’s werelds snelste…

Promotor: P.M. Brakefield

This thesis is is made of three parts. The first part describes a generalization of the Chabauty's method, that can be used to determine the rational points of a curve such that s+g>r+1, where g is the genusof the curve, r is the rank of the Mordell-Weil group of the jacobian of the curve and s is…

Big Science, commonly defined as conventional science made big in three dimensions, namely organizations, machines, and politics, brings a plethora of different stakeholders together, often for a long period of time. This includes policymakers, scientists, (scientific) managers as well as local “host”…

Anthropogenic noise negatively affects wildlife in a wide range of taxonomic groups.

The different kinds of cultural perspectives on health and disease of the participants are related to their knowledge, beliefs, values and practices manifested in various forms of lifestyle in Indonesia. The cultural diversity of the population is also related to differences in health behaviour.

The book ‘Bestrijdingsmiddelen en Milieu' gives a transparent overview of facts and figures concerning pesticide use in the Netherlands and the impact of pesticides on the environment.

Promotor: E. Gittenberger, Co-promotores: L.P. van Ofwegen; B.W. Hoeksema

Het archeologisch erfgoed van Zuid-Amerika wordt in toenemende mate bedreigd door de uitbreiding van landbouwactiviteiten, de uitbreiding van infrastructuur, illegale houtkap en de huidige bosbranden die het Amazonegebied en andere gebieden van het continent teisteren.

In this Yearbook you will find some fascinating examples of what was done in 2021, not only by ourselves, but also by our international colleagues.

Promotores: F.H. van Lunteren, F.P. Israel

Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit

Diacylglycerol lipases (DAGLα and DAGLβ) are responsible for the biosynthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG) in the brain and peripheral tissues. Selective DAGLβ inhibitors have been proposed as a potential treatment for inflammatory diseases with reduced potential for central…

Promotores: T.H.W. Bäck, A. Plaat, Co-promotor: F.J. Verbeek

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

This Thesis describes a strategy to synthesize 1,2-cis-oligosaccharides modulated by additives, such as dimethylformamide (DMF), triphenylphosphine oxide (Ph3P=O) and N-methyl(phenyl)formamide (MPF), using building blocks that carry solely benzyl type protecting groups and are therefore of uniform r…

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Carbohydrates, or sugars, are the most diverse and most abundant biomolecules known. However, the isolation of carbohydrate samples in sufficient amounts and purity is often impractical or even impossible, so the chemical synthesis of glycosides becomes relevant. The glycosylation reaction, in which…

Religie is overal. Kennis van religie is essentieel voor iedereen die de wereld wil begrijpen. Het Leids Centrum voor Religiewetenschap (LUCSoR) bestudeert religie als een menselijke activiteit, in al zijn verschijningsvormen.