Eiwitten uit het Golgi-complex van de cel op een gecontroleerde manier vernietigen. Dat is de focus van het baanbrekende onderzoek van chemicus Marta Artola. Door een nieuwe technologie te ontwikkelen gericht op specifieke eiwitten in het Golgi-complex, wil Artola nieuwe mogelijkheden voor medicijnontwikkeling…

This thesis describes the structural and biochemical characterization of the β-lactamase BlaC from Mycobacterium tuberculosis (Mtb), and the Alr and YlmE proteins from Streptomyces coelicolor A3(2).Mtb is the main cause of tuberculosis.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

The bacterial cell wall is a nearly universal structure that offers protection and gives the cell its shape. However, environmental stressors, such as cell wall-targeting antibiotics and hyperosmotic conditions, can induce bacteria to shift to a wall-deficient state. It is unknown whether the lack of…

Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.

A substance flow analysis, covering about 99 % of the flows of chlorinated substances in the Netherlands.

The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…

Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.

Creating information portals for support of European environmental policy.

The soil ecosystem consists of the largest reservoir of biodiversity on Earth.

Promotor: G.P. van Wezel, Co-promotor: Y.H. Choi

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Exploring linkages between energy and material use and implications for sustainable development.

Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

“Temminck’s Order” is the scientific biography of Coenraad Jacob Temminck (1778–1850), a Dutch naturalist and the first director of ’s Rijks Museum van Natuurlijke Historie in Leiden.

Wat zijn de belangrijkste thema's in het uitvoeren van systemen voor bio-energie ?

Zelfs embryo’s kunnen verzeild raken in een evolutionaire wapenwedloop met een andere soort. Dat laten Leidse biologen zien bij larven van de roze bittervoorn die als koekoeksjongen parasiteren op de kieuwen van zoetwatermosselen. Ze publiceerden hun onderzoek 19 februari in PNAS.

Het milieu is een mondiale zorg: de achteruitgang van het milieu en de opwarming van het klimaat treft ons allen. Het blijkt een enorme uitdaging om vanuit de internationale gemeenschap juridisch bindende en ambitieuze milieudoelstellingen op te stellen. Kunnen unilaterale handelsmaatregelen een alternatief…

Has the industrial sector in China effectively been decarbonizing in recent years, across different regions and subsectors, and is it plausible that it will reduce its CO2 emissions in conformity with national and internationally pledged emission goals?

This report investigates the different approaches in the authorization process of GMOs for commercial use in the European Union and the United States of America. Three main aspects are considered and analyzed as potential causes of differences in the authorization process of GMOs for commercial use.…

A single self-assembled semiconductor quantum dot in a high-finesse optical microcavity - the subject of this thesis - is an interesting quantum-mechanical system for future quantum applications. For instance, this system allows trapping of an extra electron and thus can serve as a spin quantum memory,…

What is the environmental impact, the human health impact and the life cycle and production costs of the lab, pilot and commercial diffusion of nanowires and nanowire-based photovoltaic technologies?

Some examples of research questions include: What framework of circular strategies should local practitioners use? How should practitioners organize their monitoring of the circular economy activities in the region of interest? What are the main products that have the most circular potential in the…

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Promotie

De ‘eh’-klank kan helpen bij het herkennen van een verdachte in afgetapte telefoongesprekken, aldus promovenda Meike de Boer. Forensische fonetiek noemen we dat. Ze vertelt erover in de podcast Wetenschap Vandaag van BNR Nieuwsradio.

Geesteswetenschappen, Centre for the Arts in Society

The project

Oratie

For questions and suggestions regarding the series, please contact prof. dr. Olaf van Vliet or dr. Max van Lent

Dr. Nadine Akkerman, werkzaam aan het Leiden University Centre for the Arts in Society (LUCAS), is van 27 mei tot en met 4 juli gastdocent bij de Universiteit van Birmingham. Ze zal onder andere meedoen aan een groot publiekelijk debat en ze is de keynote spreker tijdens het internationale colloquium…

Het ontwikkelen en demonstreren van innovatieve praktijken om met een lage milieu-impact farmaceutica te produceren.

Development of an aggregated impact indicator to measure decoupling.

How does the management of Elephant Marsh Fishery in Malawi relate to wider contexts of policies, theories and regions? And how can the current management system be adapted to achieve long-term sustainability of the fishery?

In het onderwijs bieden wij alle studenten de mogelijkheid om kennis te maken met duurzaamheidsthema’s en –vraagstukken, waar mogelijk aansluitend bij de inhoud van hun opleiding.

How can ecosystem services within river catchments be quantified in spatial and temporal explicit way?

How do you make a technology sustainable that does not even exist yet? Well, by bringing together an interdisciplinary team of pioneering European experts right at the start and paying attention to sustainability right from the development phase.

Do sustainability values play a role in motivating people to act for biodiversity in successful projects and in successful leadership action? And how could these values be incorporated in current economic valuation methods?

What are the environmental trade-offs for SMEs considering moving from monoculture aquaculture practice towards IMTA? What are the environmental trade-offs comparing IMTA species with their conventional monoculture alternatives?

Investigating epistemic and ethical practices in medical experimentation on humans in the colonial period in Southeast Asia.

Dr. Gabrielle van den Berg heeft een prestigieuze VICI-beurs ontvangen van de Nederlandse Organisatie voor Wetenschappelijk onderzoek (NWO) voor haar project 'Turks, texts and territory: Imperial ideology and cultural production in Central Eurasia'.

Intensive 5-day programme on the world-famous Antwerp-based printing and publishing house founded by Christopher Plantin in 1555. International experts will discuss how it developed the production and distribution of religious books and related illustrations and prints in the following centuries.

2.240 plantenextracten van 1.299 verschillende plantensoorten van Nederlandse bodem. Dat is de collectie van de Dutch Extract Library, die onlangs is overgebracht naar het Instituut Biologie Leiden. Voor Pingtao Ding, plantenbioloog en contactpersoon van deze bibliotheek, is dit een ware schatkamer.…

Climate change, depletion of natural resources, loss of natural and cultural landscapes, and many other (ecological) sustainability challenges urge us to (re)evaluate human interaction with the natural world. This renewed environmental consciousness has invigorated not only scientists working on effects…

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…