Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.

The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.

Als serieuze wetenschapper kun je er niet aan twijfelen: de evolutietheorie. Maar door het woord 'theorie' lijkt evolutie voor het grote publiek slechts een potentiële verklaring die je prima in twijfel kunt trekken. Evolutiebioloog Maurijn van der Zee legt bij Nemo Kennislink uit waarom dat niet zo…

Dr. Peter J. Punt, werkzaam bij TNO, is benoemd tot bijzonder hoogleraar Industriële Biotechnologie en gaat zich richten op de moleculaire genetica van filamenteuze schimmels.

Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Ook planten maken groeihormonen aan, en kennen een proces van veroudering. Het bestuderen van de genen en de mechanismen hierachter is nuttig voor gewasveredeling en landbouw, maar ook voor medisch onderzoek. Dat stelt Remko Offringa, hoogleraar Ontwikkelingsgenetica van Planten. Oratie op 16 maart.

The cannabinoid receptor type 2 (CB2R) is associated with several inflammatory diseases with an unmet medical need (e.g. Alzheimers, multiple sclerosis, reumatoid arthritis). Development of new chemical biology strategies to study this protein is essential to aid future development of drugs for these…

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet

This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Of een bacterie nuttig of schadelijk is voor een plant is nu eenvoudig en goed te voorspellen met de nieuwe software bacLIFE. Door de intuïtieve interface maakt het de geheimen van bacterie-genen veel toegankelijker. Een groep Leidse biologen presenteerde dit staaltje bioinformatica in Nature Commun…

Promotor: M. Ubbink, Co-promotor: G. Siegal

Organic molecules in interstellar space are important as they influence the structure of galaxies and star formations. Studying catalytic processes in space allows us to understand how molecular species are formed and chemically evolved in the interstellar medium and solar system objects.

Outflows are crucially important for the gas budget and evolution of luminous star-forming galaxies and AGNs, with observed mass outflow rates of the same order as the star formation rate. Greater star formation and black hole growth lead to more intense feedback and outflows, resulting in self-regulated…

With increasing carbon dioxide levels in the atmosphere and their detrimental effect on the global climate, modern society needs to push for more renewable energy sources. Storing widely accessible and abundant solar energy in chemical bonds in the form of molecular fuel via artificial photosynthesis…

Studievoorlichting

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This thesis describes how different colours of light affect various aspects of the growth and development of Arabidopsis and tomato plants⁠.

Het doel van de onderzoekers aan het LUCL is om bij te dragen aan een alomvattend en deskundig perspectief op het menselijk verleden.

Promotor: Prof.dr. P. Hooykaas, Co-promotor: R. Offringa

De master Biology is een samenwerking tussen het Instituut Biologie Leiden, Naturalis en het Centrum voor Milieuwetenschappen Leiden waardoor het programma een brede en diverse scope heeft. De opleiding biedt zeven specialisaties, waarvan vier researchspecialisaties die nauw verbonden zijn met het onderzoek…

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

Promotor: J. Schaye

This thesis explores how electron paramagnetic resonance (EPR) spectroscopy can be used to investigate key biochemical processes.

Promotor: R.C.M. Pelger Co-Promotor: G. van der Pluijm

This thesis examines the link between simple molecules and the underlying structure and chemistry within protoplanetary disks - the birthplaces of planets.

Promotor: Prof.dr. P.C. van Welzen

During the course of drug discovery translational steps are made.

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

The disease acute myeloid leukemia (AML) is characterized by fast progression and low survival rates.

This thesis describes the use of an activity-based proteomics method to study the endocannabinoid system.

This thesis describes the antimicrobial discovery strategy developed in our group, the den Hertog Group at the Hubrecht Institute. It includes a cultivation-based screening approach for novel antimicrobial agents from the source of fungi, and a bacterial time-lapse imaging approach for antimicrobial…

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

Glucocorticoids (GCs) are widely prescribed as anti-inflammatory drugs due to their well-established immunosuppressive effects.

Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda

Check hieronder de aanmelddeadlines voor de opleiding Molecular Science and Technology.

Promotie

Promotor: P.J.J. Hooykaas, Co-Promotores: P.B.F. Ouwerkerk, M. Wang

The plant hormone auxin regulates plant growth and development through polar cell-to-cell transport-generated maxima and minima. PIN FORMED (PIN) auxin efflux carriers determine the direction of this auxin flow through their asymmetric placement on the plasma membrane (PM).

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

The type-IV secretion system (T4SS) is a machinery able to transfer DNA and proteins between bacteria and in certain cases also to eukaryotic cells.