468 zoekresultaten voor “middle allows” in de Publieke website
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World Archaeology
De onderzoekers van het departement ‘World Archaeology’ van de Faculteit Archeologie richten zich in hun onderzoek op verschillende periodes en regio’s: van de oorsprong van de mens tot aan de Middeleeuwen en de moderne tijd, en van Azië tot Zuid-Amerika.
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Over deze minor
Alles wat jij moet weten over de minor De middeleeuwen en vroegmoderne tijd op een rijtje.
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Unfolding the regulation of stress response pathways upon liver injury
Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.
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Algebraic techniques for low communication secure protocols
Promotor: R. Cramer
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Algorithms for analyzing and mining real-world graphs
Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters
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Het miljard deeltjes probleem
Promotor: Prof.dr. S. Portegies Zwart
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Arithmetic of affine del Pezzo surfaces
In this thesis integral points on affine del Pezzo surfaces are studied.
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Expanding the coverage of ecosystem services in life cycle assessment: an interdisciplinary venture
To contribute to the body of knowledge aiming at a better coverage of ecosystem service assessment in LCA studies, this thesis dives into the challenges of incorporating existing ecosystem service methods within the impact assessment phase of the conventional LCA framework.
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Precision modeling of breast cancer in the CRISPR era
The molecular mechanisms that instigate a healthy cell to become malignant are fueled by (epi)genetic alterations in so-called driver genes.
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Imaging complex model catalysts in action
From surface science towards industrial practice using high-pressure scanning tunneling microscopy.
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Human skin equivalents for atopic dermatitis: investigating the role of filaggrin in the skin barrier
Promotor: Prof.dr. J.A. Bouwstra, Co-promotor: A. El Ghalbzouri
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Filter-based reconstruction methods for tomography
Promotor: K.J. Batenburg
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Systems microscopy to unravel cellular stress response signalling in drug induced liver injury
Promotor: B. van de Water
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Improvisations in phototrophy
Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.
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Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
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Analysis of Energy Systems
The Institute of Environmental Sciences has carried out and participates in several projects that deal with the analysis of energy systems.
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Probing Gravity at Cosmic Scales
The theoretical explanation of cosmic acceleration is nowadays one of the biggest puzzles in cosmology.
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Robust rules for prediction and description.
In this work, we attempt to answer the question:
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Optimizing antifungal treatment through pharmacometrics: dosing considerations to enhance outcome
Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.
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Enhanced coinduction
Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)
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Effects of heavy fields on inflationary cosmology
Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten
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Global distribution patterns of mycorrhizal associations
Mycorrhizas are symbiotic associations between soil fungi and most plant species.
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Synthesis and applications of cell wall glycopolimer fragments from Staphilococci and Enterococci
Carbohydrates are present on the surface of bacteria making them suitable antigen candidates for vaccine development. This thesis deals with the synthesis of two carbohydrate-based components; the capsular polisaccharide of S. aureus type 5 and teichoic acids from staphilococci and enterococci speci…
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: Prof.dr. J.N. Kok
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Freedom of additional signals on genes: on the combination of DNA mechanics, genetics and translation speed
DNA carries various forms of information. Out of these forms of information the most well-known is classical genetic information.
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Weighing the Dark: Cosmological Applications of Gravitational Lensing
Promotor: K. Kuijken, Co-Promotor: H. Hoekstra
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Hysterons and pathways in mechanical metamaterials
Mechanical metamaterials are carefully engineered materials whose properties are controlled by their structure, not by their composition, which allows using metamaterials to study and control physical effects in detail.
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Phenotypic screening with 3D cell-based assays
Traditional drug discovery approaches have been hampered by (in vitro) cell-culture models that poorly represent the situation in the human body.
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Development of hyaluronan-based dissolving microneedle arrays for dermal vaccination
Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.
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ReCiPe
The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).
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Invariant manifolds and applications for functional differential equations of mixed type
Promotor: S.M. Verduyn Lunel
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How Electrostatic Interactions Drive Nucleosome Binding of RNF168 & PSIP1
The studies presented in the work show the potential of the integrative use of biophysical data in defining the structural basis of protein interactions.
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Targeting the adenosinergic system
Adenosine is an endogenous ligand which exerts its action by activating adenosine receptors (ARs), while its circulating levels are controlled via a variety of mechanism and proteins, amongst others the equilibrative nucleoside transporters (ENTs).
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Studies of dust and gas in the interstellar medium of the Milky Way
Promotor: Prof.dr. A.G.G.M. Tielens
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Breaking of ensemble equivalence for complex networks
For many system in statistical physics the microcanonical and canonical ensemble are equivalent in the thermodynamic limit, but not for all.
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Gibbs-non-Gibbs transitions and vector-valued integration
Promotor: W. T. F. den Hollander, F. H. J. Redig
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Galactic substructures as tracers of dark matter and stellar evolution
One of the most important puzzles in modern astrophysics is the nature of dark matter.
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Attacks on hash functions and applications
Promotores: R. Cramer, A.K. Lenstra, Co-Promotor: B.M.M. de Weger
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Inverse electron demand Diels-Alder pyridazine elimination: synthetic tools for chemical immunology
The inverse electron demand Diels-Alder (IEDDA) pyridazine elimination emerged in 2013 as a new bioorthogonal reaction and constitutes a prime example of what is now known as dissociative bioorthogonal chemistry. The research described in this Thesis aims to develop synthetic strategies which enable…
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Mitochondria in chemical-induced toxicity
Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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Quantum computation with Majorana zero modes in superconducting circuits
Promotor: Prof.dr. C.W.J. Beenakker
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The origins of friction and the growth of graphene, investigated at the atomic scale
Promotor: J.W.M. Frenken
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Topology and Geometry in Chiral Liquids
We study the interplay of topology and geometry with chirality for several passive and active systems, employing both analytical and numerical methods.
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Benchmarking Discrete Optimization Heuristics
This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.
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Unconditionally secure cryptographic protocols from coding-theoretic primitives
This dissertation presents new cryptographic protocols, which can be divided into two families.
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Exploring chemical space in covalent and competitive glycosidase inhibitor design
Glycoside hydrolases (glycosidases/GHs) are widely abundant enzymes in all kingdoms of life and are important biocatalysts that catalyze the hydrolysis of glycosidic linkages in oligo/polysaccharides, glycoproteins and glycolipids with tremendous efficiency
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Group representations in Banach spaces and Banach lattices
Promotor: S.M. Verduyn Lunel, Co-promotores: M.F.E. de Jeu, B. de Pagter
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Foam rheology near the jamming transition
Promotor: Prof.dr. M.L. van Heck, Co-Promotor: B.P. Tighe
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Fluorescence Correlation Spectroscopy on Electron Transfer Reaction: Probing Inter- and Intramolecular Redox Processes
Promotores: G.W. Canters, T.J. Aartsma