497 zoekresultaten voor “mechanisms metamaterials” in de Publieke website
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Richting geven aan plantengroei en -ontwikkeling
Ook planten maken groeihormonen aan, en kennen een proces van veroudering. Het bestuderen van de genen en de mechanismen hierachter is nuttig voor gewasveredeling en landbouw, maar ook voor medisch onderzoek. Dat stelt Remko Offringa, hoogleraar Ontwikkelingsgenetica van Planten.
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Oratie: Aangeboren immuniteit in beeld
Tuberculosebacteriën en andere intracellulaire pathogenen gebruiken immuuncellen als paard van Troje om zich in hun gastheer te verspreiden. Annemarie Meijer, hoogleraar immunobiologie, vertelt hoe onderzoek naar mechanismen van aangeboren immuniteit in zebravissen helpt om nieuwe behandelingsmethoden…
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Regulators of integrin α6β4 function
This thesis describes our search to identify and understand possible regulatory mechanisms of integrin α6β4 in cell-matrix adhesion and intracelular signaling.
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Martin van Hecke nieuwe APS-fellow
Onderzoeker van metamaterialen Martin van Hecke is door de American Physical Society (APS) verkozen als fellow, een eer die slechts voor een half procent van de leden weggelegd is.
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The use of activity based protein profiling to study proteasome biology
Promotor: H.S. Overkleeft, Co-Promotor: B.I. Florea
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Design of homogeneous water oxidation catalysts
To design the ideal water oxidation catalyst, understanding of the catalytic mechanism and decomposition pathways is essential.
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Identification of Therapeutic Targets and Antisense Oligonucleotide Mediated Exon Skipping Based Therapies in Arthritis
Promotor: G.J.B. van Ommen
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Microvasculature in Microfluidics: matching complexity with compatibility
In vitro disease models play a fundamental role in drug research. They enable the systemic identification and validation of disease mechanisms and the discovery of possible drug targets. However, more than often, drug candidates that are identified in vitro fail in the later clinical stages of drug…
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Online Course International Law in Action: The Arbitration of International Disputes
This course explores international arbitration as one of the most common methods of international dispute settlement. You will gain an in-depth understanding of international arbitration through the analysis of its role as a mechanism of dispute settlement, its institutions, the fields of law it is…
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Predictors, symptom dynamics and neural mechanisms of bipolar disorders
Promotie
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Characterization of DNA-replication proteins and their molecular mechanisms
Promotie
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Mechanisms of autoantigen generation in Type 1 Diabetes
Promotie
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Clinical aspects and pathophysiological mechanisms of (systemic) right ventricular failure
Promotie
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Modifying the modifier: Discovering mechanisms of SMCHD1 mediated chromatin repression
Promotie
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Unravelling molecular mechanisms in transcription-coupled nucleotide excision repair
Promotie
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Nucleotide excision repair: from molecular mechanisms to patiënt phenotypes
Promotie
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Global distribution patterns of distinct mycorrhizal types and ecological drivers of these patterns
What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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The electrochemical reduction of dioxygen and hydrogen peroxide by molecular copper catalysts
The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…
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Like me or else...
Nature, nurture and neural mechanisms of social emotion regulation in childhood
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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Fundamenteel onderzoek: Onderliggende mechanisme van ziekte en welzijn
Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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Compressed Σ-Protocol Theory
In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.
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Structure dependence of molecular reactions on surfaces
The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Regulering en ICT
Op welke manieren hebben ontwikkeling van digitale technologieën invloed op de samenleving en de regulerings- en juridische kaders binnen de samenleving?
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
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Florian Schneider
Gamic Learning in East Asian Studies - Wat kunnen spellen ons vertellen over de manier waarop mensen leren?
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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Electrocatalytic reduction of CO2 and nitrate on immobilized metal porphyrins
M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid
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CO oxidation catalysis at multiple length scales
Promotor: J.W.M. Frenken Co-Promotor: R. Felici
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The physics of nanowire superconducting single-photon detectors
Promotores: Prof.dr. D. Bouwmeester, Prof.dr. A. Fiore (TU Eindhoven)
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Morphogenesis and protein production in Aspergillus niger
Promotores: C.A.M.J.J. van den Hondel, V. Meyer, Co-promotor: A.F.J. Ram
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Search and rescue: tackling antibiotic resistance with chemistry
With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.
- Epigenetica: of waarom een lapjeskat een lapjeskat is
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Breaking barriers: unraveling response mechanisms to immunotherapy in breast cancer
Promotie
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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Center for Interdisciplinary Placebo Studies Leiden
Het Center for Interdisciplinary Placebo Studies Leiden (IPS) streeft naar een beter begrip van placebo- en nocebo-effecten, hun onderliggende mechanismen en hun mogelijke toepassingen in de klinische praktijk. IPS bestaat uit een groep interdisciplinaire onderzoekers die werken aan de Universiteit…
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Het lerarentekort als gewichtige uitdaging: Schoolleiderschap, werkklimaat en leerklimaat op scholen met een hoge schoolweging.
Welke rol spelen de leiderschapsstijl en de visie op leraren en leerlingen van schoolleiders in het bevorderen van een positief werkklimaat voor leraren en een positief leerklimaat voor leerlingen op scholen met een hoge schoolweging?
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Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
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Evolutionary diversification of Nepenthes (Nepenthaceae)
Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes