1,039 zoekresultaten voor “high both deeltijd” in de Publieke website
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T-CYCLE EPR: Development at 275 GHz for the study of reaction kinetics & intermediates
A difficulty of studies on chemical kinetics are the reaction time scales and detection of their intermediates.
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Speeddaten met vrouwelijke natuurkundigen, high tea en zelf onderzoek doen op de Physics Ladies’ Day
Speeddates met studentes Natuurkunde en vrouwelijke (technisch) natuurkundigen uit het bedrijfsleven, een college volgen van natuurkundige prof.dr. Doris Heinrich, zelf onderzoek doen en een High Tea. Daarvoor kwamen zo'n 90 meisjes naar de Physics Ladies's Day op 31 oktober.
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Microbial communities in Pampa soils; impact of land use changes, soil type and climatic conditions
Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae
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Discovery of antibiotics and their targets in multidrug-resistant bacteria
Global healthcare is on the verge of an antibiotic availability crisis as bacteria have evolved resistance to nearly all known antibacterials. Identifying new antibiotics that operate via novel modes-of-action is therefore of high priority.
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Modelling metastatic melanoma in zebrafish
Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.
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Dynamics of TNFalpha signaling and drug-related toxicity
In previous studies at our laboratory it was demonstrated that drug exposure of HepG2 cells can lead to an altered TNFα-induced NF-κB oscillatory phenotype, concurrent with a synergistically increased sensitivity for TNFα-induced apoptosis.
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Discovery of novel inhibitors to investigate diacylglycerol lipases and α/β hydrolase domain 16A
Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt
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Breeding birds on organic and conventional arable farms
Promotor: G.R. de Snoo
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Orion's Dragon and Other Stories
Stellar feedback is a crucial ingredient in the evolution of galaxies.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Development of personalized health monitoring using ultra-weak photon emission based on systems medicine concepts
Promotor: Jan van der Greef; Co-promotors: Mei Wang; Eduard van Wijk
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Guiding evolutionary search towards innovative solutions
Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)
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Bridging the gap between physics and chemistry in early stages of star formation
A dense region of a gaseous and dusty cloud collapses to form a protostar surrounded by a disk and an envelope. This thesis uses both observations and models to study physical and chemical conditions of these protostellar systems which are likely where planets start to form.
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Fire and grazers in the West African savanna
Promotores: H.A. Udo de Haes, H.H.T. Prins, Co-promotor: H.H. de Iongh
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Gene networks-based mechanistic assessment of drug-induced organ toxicity: a focus on liver and kidney
Drug induced organ toxicity is the main problem of the drug development and drug usage in the clinic. The liver and kidneys are the most sensitive organs towards drug induced toxicity.
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Student Information
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In vivo modelling of Ewing sarcoma in zebrafish
Promotores: Prof.dr. P.C.W. Hogendoorn & Prof.dr. H.P. Spaink Co-promotor: Dr. B.E. Snaar-Jagalska
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Unraveling the surface formation of regular and deuterated water in space: a combined laboratory and computational study
Promotor: Prof.dr. H.V.J. Linnartz
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Star formation and aging at cosmic noon: the spectral evolution of galaxies from z=2
Promotores: Prof.dr. M. Franx, Prof.dr. P.G. van Dokkum (Yale University)
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Star-Forming Galaxies at the Cosmic Dawn
Promotor: Prof.dr. M. Franx, Co-Promotor: Rychard Bouwens
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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Van woord tot akkoord. Een analyse van de partijkeuzes in CPB-doorrekeningen van verkiezingsprogramma's en regeerakkoorden, 1986-2017
This PhD-thesis analyses the relationship between the parties’ choices in the CPB Netherlands Bureau for Economic Policy Analysis’ assessments of the election manifestos and coalition agreements over the period 1986-2017, and tries to explain this relationship.
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Corpora Non Agunt Nisi Fixata: Ligand Receptor Binding Kinetics in G Protein-Coupled Receptors
The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.
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Discovering the preference hypervolume: an interactive model for real world computational co-creativity
In this thesis it is posed that the central object of preference discovery is a co-creative process in which the Other can be represented by a machine. It explores efficient methods to enhance introverted intuition using extraverted intuition's communication lines.
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Atomic Insights into Hydrodesulfurization
Hydrodesulfurization (HDS) is an ubiquitous part of oil refining that ensures that fuels are cleaned of impurities and environment release of pollutants such as SOx and NOx gasses are minimized.
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Metabolomics assisted with stable-isotope labeling: exploring neuronal metabolism related to Parkinson’s disease
The progressive loss and degeneration of dopaminergic neurons is a major pathological hallmark of Parkinson's disease (PD). The onset and progression of PD can be triggered by multiple risk factors, for instance, genetic mutation, environmental exposure, and aging.
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Shaping Massive Galaxies: the structural evolution of galaxies across
Galaxies in the local Universe fall into two main categories of spirals and ellipticals. In this Thesis, we explore the structural evolution of galaxies into this bimodal distribution.
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Design and development of a comprehensive data management platform for cytomics: cytomicsDB
Promotor: Prof.dr. J.N. Kok
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Extremely loud & incredibly far: observing radio bright AGN into the cosmic dawn
In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…
- Dual-Appointment PhD Candidate and Junior System Administrator, Software Optimization and Compiler
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Assistant Professor (1.0 FTE)
Governance and Global Affairs, Institute of Security and Global Affairs
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Cholesterol metabolism in mouse models of atherosclerosis and adrenal steroidogenesis
Cholesterol influences many pathways, including serving as precursor for adrenal steroidogenesis. Imbalance of cholesterol levels has been implicated in several diseases including cardiovascular diseases and its underlying pathology, atherosclerosis.
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Imaging polarimetry for the characterisation of exoplanets and protoplanetary discs. Scientific and technical challenges
Promotor: Prof.dr. C.U. Keller
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Full Professor (Chair) in International Institutional Law (Schermers Chair) (0,2 FTE)
Rechtsgeleerdheid, Instituut voor Publiekrecht, Grotius Centre for International Legal Studies
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Hunting for new physics in the primordial Universe
This thesis contributes to studying primordial cosmology theories and their detectability in future observations.
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Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT)
Description of Development of a low cost technology for in-situ treatment of groundwater for potable and irrigation purposes (TiPOT) (2004 - 2007)
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Transforming data into knowledge for intelligent decision-making in early drug discovery
Promotor: A.P.IJzerman Co-promotor: A. Bender
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Rare Earth Supply Chain and Industrial Ecosystem: A Material Flow Assessment of European Union
1) Assess the trends in supply and production status of these critical minerals and mineral products worldwide and Europe’s dependence including on intermediate products such as permanent magnets, RE based super alloys, batteries, polishing compounds, phosphors, catalysts etc. 2) Trace the entire value…
- Symposia 2023-2024
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Inferno Worlds
A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.
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Between Myth and Reality: Rules Of Observance As Texts Of Life In The High Middle Ages (RUG, 11 March 2024)
On the occasion of the appearance of the monograph "Varieties of the Self.Peter Abelard and the Mental Architecture of the Paraclete" written by Babette Hellemans and published at Brill in 2023, a workshop will be organized concerning rules of observance as ‘texts of life’ in ascetic communities. The…
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Electrocatalytic reduction of CO2 and nitrate on immobilized metal porphyrins
M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid
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High throughput glycomics workflows
Promotie
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The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
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PhD position: ultrafast broadband-THz spectroscopy of perovskite materials
Wiskunde en Natuurwetenschappen, Leids Instituut voor Chemisch Onderzoek (LIC)
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PhD candidate combinatorial drug discovery with macrocycles
Wiskunde en Natuurwetenschappen, Leiden Academic Centre for Drug Research (LACDR)
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Educatieve minor
Heb je interesse in lesgeven in het voortgezet onderwijs? Tijdens de Educatieve minor word je opgeleid tot docent in het voorgezet onderwijs. Na het succesvol afronden van de Educatieve minor én je vakbachelor ben je gekwalificeerd om les te geven in jouw vakgebied in de onderbouw van havo/vwo en het…
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From supernovae to galaxy clusters: observing the chemical enrichment in the hot intra-cluster medium
Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa
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Adaptive Streaming Applications: Analysis and Implementation Models
Promotor: Prof.dr. E. Deprettere