828 zoekresultaten voor “gene theory” in de Publieke website
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Cryptography from quantum uncertainty in the presence of quantum side information
Promotor: Ronald Cramer, Co-promotor: Serge Fehr
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On continued fraction algorithms
Promotor: Robert Tijdeman, Co-promotor: Cornelis Kraaikamp
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Positive representations on ordered Banach spaces
Promotor: A. Doelman, Co-promotor: M.F.E. de Jeu
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Hunting for new physics in the primordial Universe
This thesis contributes to studying primordial cosmology theories and their detectability in future observations.
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Chenyu Shi
Wiskunde en Natuurwetenschappen
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Accurate modeling of the dynamics of dissociative chemisorption on metal surfaces
Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.
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A fixed point approach towards stability of delay differential equations with applications to neural networks
Promotor: S.M. Verduyn Lunel, Co-Promotor: O.W. van Gaans
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Multi-omics studies of the control of growth and antibiotic production of Streptomyces
Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).
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Hydrogen dissociation on metal surfaces
Dissociative chemisorption is an important reaction step in many catalytic reactions.
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Hydrogen dissociation on metal surfaces
Promotor: G. J. Kroes
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Observing what cannot be observed: computational electrochemistry from carbon to hydrogen
In this thesis, we consider various (electro)chemical phenomena at surfaces and nanoparticles and their underlying atomistic processes, which we studied using first-principles methods such as density functional theory.
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Understanding the Surface Structure of Catalysts and 2D Materials at the Atomic Scale
The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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Key innate immune components controlling intracellular infection
Promotor: H.P. Spaink, Co-Promotor: A.H. Meijer
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Aquatic eDNA: Beyond Species Presence
As a non-invasive genetic method, eDNA based approaches have become an important component of ecologists' and environmental managers' toolkits for biomonitoring in conservation and an increasingly important source of ecological knowledge.
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On the 16-rank of class groups of quadratic number fields
Promotores: P. Stevenhagen, E. Fouvry (Univeriste Paris Saclay)
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De deugden van een wetenschapper
Waarom spraken negentiende-eeuwse wetenschappers zo graag over toewijding, vlijt en ijver? Waarom wijdde Robert Fruin zijn oratie aan onpartijdigheid en riep Abraham Kuenen zijn studenten op tot waarheidsliefde?
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Models of curves: The Birch and Swinnerton-Dyer conjecture & ordinary reduction
Chapter 1,contains the numerical verification of the Birch and Swinnerton-Dyer conjecture for hundreds of Jacobians of hyperelliptic curves of genus 2, 3, 4 and 5.
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Aria of the Dutch North Sea
Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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The Role of Linker DNA in Chromatin Fibers
The genetic information of all living organisms is contained in their DNA. Cells modify the degree of DNA compaction by epigenetics, which largely determines what genes are read out and which genes are transcriptionally silent.
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Universal adelic groups for imaginary quadratic number fields and elliptic curves
Promotor: Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Univ. de Bordeaux)
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Inverse Jacobian and related topics for certain superelliptic curves
To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.
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The unit residue group
The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.
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Molecular engineering of plant development using Agrobacterium-mediated protein translocation
Supervisor: P.J.J. Hooykaas Co-Supervisor: R. Offringa
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Highly Accurate Simulations and Benchmarking of Molecule-Surface Reactions
Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.
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Geometry of Vegetation Pattern
One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.
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Geometric approach to evolution problems in metric spaces
Promotor: S.M. Verduyn Lunel, Co-promotor: O.W. van Gaans
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Freedom of Additional Signals on Genes
Promotie
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Functions of leptin in tuberculosis and diabetes: multi-omics studies across species
In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.
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MYC transcription factors: masters in the regulation of jasmonate biosynthesis in Arabidopsis thaliana
Promotor: J.M. Memelink
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Signatures of Majorana zero-modes in nanowires, quantum spin Hall edges, and quantum dots
Promotor: Prof.dr. C.W.J. Beenakker
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Hybrid zone dynamics in amphibians
Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.
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Dynamic organization of bacterial chromatin by DNA bridging proteins
Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.
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Evaluation of the zebrafish embryo as an alternative model for hepatotoxicity testing
Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis
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Chemical genetic approaches for target validation
Drug development is a time- and resource-consuming process that starts with the discovery and validation of a (protein) target that contributes to pathogenesis or disease progression.
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Rahul Bandyopadhyay
Wiskunde en Natuurwetenschappen
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Development of highly accurate density functionals for H2 dissociation on transition metals
Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).
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Personalized drug repositioning using gene expression
Promotie
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Exploring and exploiting the mechanism of mycelial pellet formation by Streptomyces
Promotor: G.P. van Wezel
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Functional analysis of agrobacterium tumefaciens virulence protein VirD5
Supervisor: P.J.J. Hooykaas
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Innate immune modulation in atherosclerosis and vascular
Promotores: Prof.dr. J. Kuiper, Prof.dr. P.H.A. Quax, Co-promotor: I. Bot
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Involvement of host and bacterial factors in Agrobacterium-mediated transformation
Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.
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Resistance to PARP inhibition by DNA damage response alterations in BRCA1/2-deficient tumors
Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.
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Solvent tolerance mechanisms in Pseudomonas putida
Bacterial biocatalysis constitutes a sustainable alternative for high-value chemicals production by enabling the utilization of renewable feedstocks.
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Multiple Scales: theory and applications
Congres/symposium
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Computational aspects of class group actions and applications to post-quantum cryptography
Most of current public-key cryptography is considered insecure against attacks from sufficiently powerful quantum computers. Post-quantum cryptography studies methods to secure information resistant against such attacks. One proposal is isogeny-based cryptography, which bases its security on computational…
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Stochastic resetting and hierarchical synchronisation
Stochastic resetting is simple enough to be approached analytically, yet modifies stochastic processes in a non-trivial way.
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Counting problems for number rings
Promotor: H.W. Lenstra