Do e-waste workers display enhanced effects of adverse health effects due to informal e-waste processing in Nigeria? Is there a difference between the health outcomes of the exposed and the control groups? Are there difference in health effects within and between job groups (collectors, dismantlers,…

Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

To this day, all cyclophellitol-based inhibitors and ABPs have been close analogues of their natural substrate counterparts. As a result, these probes showed high selectivity towards their target glycosidases.

Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'

Comparing the global warming potential (GWP) of the service provided by an iRex Digital Reader to the same service provided by an office printer using a scanning LCA.

Promotor: F.S. de Boer, Co-promotor: M.M. Bonsangue

Announcement of the publication of Vamping the Stage: Female Voices of Asian Modernities, the first book-length study of women, modernity, and popular music in Asia (University of Hawai'i Press, 2017).

GLOBOX is a spatially differentiated multimedia fate, exposure and effect model. It is used for the calculation of spatially differentiated LCA characterisation factors on a global scale.

Pharmaceutical companies, governments and the general public have become increasingly aware that animal models used in drug testing lack vital aspects to serve as an accurate representation of human biology. As models of the human body should become more physiologically relevant, animal models no longer…

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

Intensive 5-day programme on the world-famous Antwerp-based printing and publishing house founded by Christopher Plantin in 1555. International experts will discuss how it developed the production and distribution of religious books and related illustrations and prints in the following centuries.

In June 2024, the University of Groningen organizes a summer school, titled "Things that Matter". The Summer School explores challenges in digitizing source materials, questioning distinctions between physical and digital copies. It delves into the impact of virtual collections and criteria for digitization,…

World Teachers Festival 2024 - Celebrating and exploring language, culture, diversity and criticality in teaching and learning

Menig student ziet op tegen het schrijven van een scriptie. De praktijkgerichte scriptie van masterstudent Laura Robustella laat zien dat het wél meer dan de moeite waard is. Op basis van haar masterscriptie ontwikkelde ze een kunsttentoonstelling.

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

An interdisciplinary collection of the best international scholarship on Muslim youth.

In de serie tafelgesprekken ‘Van kluis naar kussen’ krijgt de kijker een blik achter de schermen van de Bijzondere Collecties. In deze speciale uitzending staat de zomertentoonstelling 'Books that made History' van de Universitaire Bibliotheken Leiden en het Rijksmuseum van Oudheden centraal. In de…

The clinical potential of applying synthetic lethality to cancer treatment is famously demonstrated by the BRCA1/PARP1 paradigm: a tumor specific defect in BRCA1 – a component of the DNA double-strand break (DSB) repair pathway homologous recombination (HR) – results in a remarkable sensitivity to PARP1…

African oral literatures, new media and technologies: challenges for research and documentation

Development of an aggregated impact indicator to measure decoupling.

Promotores: Prof.dr. J.N. Kok, Prof.dr. C.A. Mandemakers, Co-Promotor: G. Bloothooft

Hoe kan de techniek van cell wall engineering worden ingezet zodat de industrie streptomyceten beter kunnen verwerken tot nieuwe antibiotica?

Geesteswetenschappen, Centre for the Arts in Society

The project

Promotores: S.J. Edixhoven, P.Parent

Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…

This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…

Did the Jochids leave their mark on the Grand Duchy, taking into account that the Lithuanian state was one of the main successor states of the Great Horde in the 16thCentury?

Hifadhi ya Dijiti ya Ustadh Mau

Promotor: Prof.dr. G.P. van Wezel

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Acidobacteria is a widely distributed phylum but their functional roles in ecosystem processes are still largely elusive.

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?

Op Things That Talk, een website opgericht en ontwikkeld door Fresco Sam-Sin, beschrijven studenten en onderzoekers objecten van vandaag en lang geleden. Inmiddels zijn meer dan honderd objecten aan bod gekomen. Willemijn Waal, Emma Verweij en Frank van den Boom werken mee aan de content.

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

CONSENT (Consumer sentiment regarding privacy on user generated content services in the digital economy) is a research project funded by the European Union under the 7th Framework Programme. The question central to this research is whether recent changes to consumer and commercial practices developed…

CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…

Tentoonstelling