Promotor: C.J. ten Cate, Co-promotor: H.W. Slabbekoorn

Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver

Promotor: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Co-promotor: H.H. de Iongh

This thesis is devoted to an in-depth examination of the various effects of disorder in the cuprate high-temperature superconductors.

Voor het eerst is onderzocht hoe de gezondheid van gedetineerden voorafgaand aan de detentie verschilt van niet-gedetineerden en in welke mate de gezondheidsproblemen veranderen over de tijd: van vóór naar ná de detentieperiode.

Promotie

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

Promotor: Prof.dr. W.J.G.M. Peijnenburg

Curved single crystals provide variable, but well-defined surface structures.

The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

To limit the effects of climate change, global average temperature since pre-industrial measurements are to be kept well below 2 °C preferably even at 1.5 °C.

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

Een stabiele woonsituatie is belangrijk voor een goede terugkeer van een gedetineerde in de samenleving. Hoe ziet de woonsituatie van (ex-)gedetineerden eruit? En wat is de invloed ervan op recidive? Promotie op 16 januari 2020.

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Although nanoparticles are extensively used in various applications like consumer products and have most probably entered the environment, little is known about the effects of these particles on living organisms.

Promotor: Prof.dr. H.J.A. Rottgering

Promotores: H. Schiessel, G.T. Barkema

The external tissues of plants and animals are colonized by microbial communities termed microbiota. When organisms are exposed to environmental pollutants, these substances will therefore encounter microbiota at the exposure interface.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

Promotor: E.F. Smets, Co-promotor: J. Geml

We explored the Universe using weak gravitational lensing, a phenomenon that occurs when light from distant galaxies is bent by the gravitational fields of closer cosmic objects, much like how a lens distorts light.

The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.

One of the effects of climate change is the phenomenon of desertification, a process that occurs in semi-arid and arid areas and causes land degradation as well as vegetation loss. Due to the lack of resources, vegetation self-organizes to sustain itself by forming large-scale spatial patterns.

Novel entities may pose risks to humans and the environment. The small particle size and relatively large surface area of micro- and nanoparticles (MNPs) make them capable of adsorbing other novel entities, leading to the formation of aggregated contamination.

In this thesis unconventional tools based on fluidic interfaces were developed to study the surface and interfacial chemistry of graphene, to characterize the intrinsic properties of graphene, to disentangle the effects of substrate and of the environmental factors, and to improve handling protocols…

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

Promotor: Prof.dr. A.P. IJzerman, Co-Promotor: L.H. Heitman

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

Effects of maternal smoking, premature birth, intra-uterine growth retardation and asphyxia on child development.

In this course, you will learn about sustainability and staying with the environmental boundaries of our planet. You will gain an understanding of the effects of growing affluence and population growth, the key challenges we are facing, and ways to influence your direct environment.

Economic Anthropologist Erik Bähre talks on the Dutch News Radio Channel BNR about the effects of the Russia-Ukraine grain agreement for African countries.

Lezing, Tuesday Talks: Science Insights

Lezing, Com(parative) Syn(tax) Series

De Landelijke Werkgroep Kind en Ouder in de Strafrechtsketen (KOS) heeft als doel de zichtbaarheid en behandeling van ouders en kinderen in de Nederlandse strafrechtsketen te verbeteren door een combinatie van centralisatie, advies en onderzoek.

Om een valide strafsysteem te behouden, moet je de grotere vragen rondom straffen blijven stellen: waarom straffen we? Wat mag de overheid wel en niet op dit gebied? Rechtsfilosoof Jeroen ten Voorde bekijkt dit soort vraagstukken en houdt zijn wetenschappelijke collega's en het publiek scherp.

Leiden Law Cast is een podcast voor iedereen die meer wil weten over actuele juridische onderwerpen, gemaakt door de Faculteit der Rechtsgeleerdheid van de Universiteit Leiden.

'Als je naar Cuba wilt, moet je wel snel zijn', wordt er vaak gezegd. Alsof op Cuba de tijd pas is gaan lopen sinds het bezoek van Obama en het concert van The Rolling Stones in 2016, alsof de tijd zou hebben stilgestaan sinds de Cubaanse Revolutie in 1959.

Op 16 januari 2020 verdedigde Maaike Wensveen haar proefschrift 'Eigen haard is goud waard?'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Nieuwbeerta en dr. J.M.H. Palmen.

Positieve verwachtingen kunnen het gevoel van jeuk beïnvloeden en placebo-effecten oproepen, terwijl negatieve verwachtingen nocebo-effecten bij jeuk kunnen veroorzaken. Er zijn aanwijzingen dat placebo-effecten ook kunnen optreden wanneer mensen weten dat zij een placebo innemen. Er is weinig bekend…

Plants and soils from natural ecosystems harbor great diversity of soil microorganisms, which could potentially contribute to the sustainability of horticulture. The knowledge about using wild plant species and soil from natural ecosystem to improve the crop health will advance the application of ecological…

Welke rol spelen stress en angst bij de vorming van nocebo hyperalgesie?

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

Promotie

Promotie

An overview is given of the flows of chlorine and chlorinated hydrocarbons through the Europian Union.

The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.