498 zoekresultaten voor “come chemistry” in de Publieke website
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Activity-Based Proteasome Profiling
Promotor: Prof.dr. H.S. Overkleeft
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De moleculaire geheimen van medicinale cannabis
Chronische pijn, misselijkheid of braken door chemotherapie. Als je er last van hebt, kan medicinale cannabis een uitkomst zijn. Het nadeel is alleen wel dat patiënten er high van kunnen worden. Leidse onderzoekers van het Oncode Instituut doen daarom onderzoek naar alternatieven waar je dat niet van…
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Postdoctoral Researcher in Machine Learning for Quantum Systems
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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PhD in Machine Learning for Quantum Systems
Wiskunde en Natuurwetenschappen, Leiden Institute of Advanced Computer Science (LIACS)
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Search and Rescue: Tackling antibiotic resistance with chemistry
Promotie
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Bridging the gap between experts and the general public
How can we bridge the gap between experts and the general public?
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Studying through the summer?
Leiden University offers a unique range of summer courses where you can broaden or deepen your knowledge or share your expertise with fellow students. The choice of academic courses is very diverse, ranging from Law, Big Data, Languages and Linguistics to Maths and Natural Sciences, Biology, Biomedical…
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The Agta of the Northern Sierra Madre. Livelihood strategies and resilience among Philippine hunter-gatherers
Promotores: G. Persoon, R. Schefold
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Willie PeijnenburgWiskunde en Natuurwetenschappen
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Wetenschappers vinden achterdeur voor medicijnen
Een team van onderzoekers, onder wie chemicus Mario van der Stelt, heeft een nieuwe manier ontdekt om een van de menselijke kernreceptoren te blokkeren. De onderzoekers verwachten dat hun vinding een flinke impact heeft in de wereld van medicijnonderzoek. Publicatie in Nature Communications.
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Biotic ligand models
Description of Biotic ligand models: making an inventory of available models & assessment of the variability of the predicted HC5 using the BLMs in different Dutch water types (2005 - 2007)
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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Applications of topology to Weyl semimetals and quantum computing
This thesis covers various applications of topology in condensed matter physics and quantum information.
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Exploring structure dependencies of gas-surface interactions with curved single crystals
Curved single crystals provide variable, but well-defined surface structures.
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Development of homogeneous catalysts for the selective conversion of levulinic acid to caprolactam
Promotors: Prof.dr. E. Bouwman, Prof.dr. E. Drent
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UV Photodesorption and Photoconversion of Interstellar Ices
This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.
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1 PhD Candidate to study transcription factor binding to chromatin at the single-molecule level
Wiskunde en Natuurwetenschappen, Leids Instituut voor Onderzoek in de Natuurkunde (LION)
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Met twee beurzen hard in de aanval om de hersentumor glioblastoom aan te pakken
Weinig onderzoekers zien heil in onderzoek naar glioblastoom, een ongeneselijke hersentumor. Alexander Kros bracht collega’s bij elkaar die de uitdaging aangaan. Europese onderzoeksfinancier ERC stelde onlangs 10,6 miljoen euro ter beschikking, een jaar eerder stelde NWO 3 miljoen euro beschikbaar.…
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Hermen Overkleeft wint de 2015 Jeremy Knowles Award
Prof. Hermen Overkleeft is bekroond met de 2015 Jeremy Knowles Award van de Royal Society of Chemistry voor zijn innovatieve en inzichtelijke ontwikkeling van activity-based eiwit probes voor de beeldvorming en de identificatie van enzymen in gezondheid en ziekte. Van Overkleeft is in Leiden verbonden…
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Origami metamaterials : design, symmetries, and combinatorics
In the first part of this thesis we study the geometry of folding patterns.
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The urge to collect
Where does the urge to collect come from? What are the explicit or underlying reasons for gathering large amount of objects?
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Approach to Markov Operators on Spaces of Measures by means of equicontinuity
The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.
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Disentangling a complex genus: systematics, biogeography and bioactivity of the genus Phyllanthus L. and related genera of tribe Phyllantheae
The largest genus within the Phyllanthaceae family is a group called Phyllanthus L. Recent studies have shown, that Phyllanthus is paraphyletic with the genera Glochidion, Breynia and Synostemon nested within it.
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Withstanding the cold: energy feedback in simulations of galaxies that include a cold interstellar medium
Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…
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Understanding the uptake and internal distribution of metallic nanoparticles in Danio rerio larvae
The aim is to discover where differently shaped metal nanoparticles distributes in Danio rerio, linking the distribution with genomic responses and so come up with a Mode of Action.
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Electrochemical and surface studies of the effect of naphthalene-based additives on tin electrodeposition
Tin electrodeposition applications have rapidly evolved in the past 25 years.
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Self-Adjusting Surrogate-Assisted Optimization Techniques for Expensive Constrained Black Box ProblemsBagheri, S.
Optimization tasks in practice have multifaceted challenges as they are often black box, subject to multiple equality and inequality constraints and expensive to evaluate.
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Principles of Environmental Sciences
Principles of Environmental Sciences provides a comprehensive picture of the principles, concepts and methods that are applicable to problems originating from the interaction between the living and non-living environment and mankind. Both the analysis of such problems and the way solutions to environmental…
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Cross-border Claims to Cultural Objects
Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).
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Reasoning about object-oriented programs: from classes to interfaces
Throughout the history of computer science, a major challenge has been how to assert that software is free of bugs and works as intended. Software bugs can lead to serious negative impacts on any software system. Throughout the main body of the thesis, we implemented a series of studies on exploring…
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Synthetic, Physical and Computational Chemistry of Propeller-shaped Polycyclic Aromatic Hydrocarbons
Promotie
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Bridging the gap between physics and chemistry in early stages of star formation
Promotie
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Duurzaamheid in onderwijs
In het onderwijs bieden wij alle studenten de mogelijkheid om kennis te maken met duurzaamheidsthema’s en –vraagstukken, waar mogelijk aansluitend bij de inhoud van hun opleiding.
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Onze mensen
Dit zijn de mensen die binnen de Universiteit Leiden actief zijn op het gebied van kunstmatige intelligentie.
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Inextricable ties between chemical complexity and dynamics of embedded protostellar regions
Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh
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Discovery of BUB1 kinase inhibitors for the treatment of cancer
The spindle-assembly checkpoint (SAC) is a safety mechanism which secures accurate chromosome segregation during mitosis.
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Linking simple molecules to grain evolution across planet-forming disks
Planets are formed in disks of gas and dust around young stars.
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Molecules during stellar formation and death
Promotor: Prof.dr. E. F. van Dishoeck
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Optical properties of DNA-hosted silver clusters
Promotor: D. Bouwmeester, Co-promotor: D. Kraft
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Synthesis of phosphodiester-containing bacterial cell wall components: teichoic acids, capsular polysaccharides and phosphatidyl glycerol analogues
Promotor: G.A. van der Marel, Co-promotor: J.D.C. Codée
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Infrared spectroscopy of astrophysically relevant hydrocarbons
This thesis is about the study of hydrocarbons via infrared spectroscopy.
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1,2-cis-glycosylations: method development and synthesis of complex oligosaccharides
Promotor: G.A. van der Marel, Co-promotor: D.C. Codée
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Hydrocarbons in interstellar ice analogues: UV-vis spectroscopy and VUV photochemistry
Promotor: Prof.dr. H.L.V. Linnartz
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Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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Automated de novo metabolite identification with mass spectrometry and cheminformatics
Promotor: T. Hankemeier, Co-Promotores: T. Reijmers, L. Coulier
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Mesoporous silica nanoparticle-based protein delivery systems for biomedical applications
Promotor: A. Kros
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Random walks and the contact process
Promotores: W. Th. F. den Hollander, M.O. Heydenreich
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Education
The specialisation Science Communication and Society (SCS) concerns science communication in a broad sense. The program focuses on the link between science and society and covers knowledge and skills in the field of science communication.
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Soil legacy effects on aboveground plant-insect interactions
In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.