De specialisatie Economics and Governance van de Master Public Administration leert je probleemoplossende benaderingen te formuleren voor concrete beleidskwesties die zich bevinden op het snijvlak van economie en openbaar bestuur, met specifieke aandacht voor welvaartsstaten en markten. Deze specialisatie…

High-angular-resolution observations of the circumstellar material have uncovered numerous and very diverse substructures in protoplanetary discs, raising the question of whether they are caused by forming planets or other mechanisms.

De master Management van de Publieke Sector biedt studenten de mogelijkheid om een gewenst pakket aan vakken en thema’s samen te stellen. De keuzemogelijkheden zijn afhankelijk van de gekozen specialisatie: de dagopleiding (start: september) of de avondopleiding (start: februari).

Hoe kan een CLIL-aanpak, met een focus op Disciplinary Literacies, het literatuuronderwijs van het LLA-programma in de bovenbouw van TTO verbeteren?

Research & Politics (RAP) is a peer-reviewed open access journal which focusses on research in political science and related fields through open access publication of the very best cutting-edge research and policy analysis. The journal achieved a high score for the impact factor, which puts it in 49th…

Een kapje over je drankje in de kroeg, deodorant als pepperspray of een koptelefoon om catcalling niet te horen: veel vrouwen zetten alledaagse voorwerpen in om zich veiliger te voelen in de openbare ruimte. Student Anne van der Linden maakte er een online tentoonstelling over.

Technology can drive peace and justice. Innovative solutions increasingly make use of new types of data, mobile technologies and social media. Big or small (data), high-tech or low-tech: the challenge is to maximise the benefits while minimising the risks that come with the so-called data revolution…

In het BNR Lobbypanel wordt elke week een onderwerp uitgelicht dat op het snijvlak van ondernemerschap en politiek ligt. Arco Timmermans, Bijzonder Hoogleraar Public Affairs, praat deze week mee over het effect van de Brexit op het lobbyen in de EU.

Wat is onze toekomst met quantum en hoe betrekken we mensen daarbij? Om die vraag draaide het Gala voor Quantum en Samenleving in een uitverkocht TivoliVredenburg op 14 maart. Leidse onderzoekers Julia Cramer en Evert van Nieuwenburg waren erbij.

Promotie

Promotie

Op 5 december 2019 gaf Rechter Christine van den Wyngaert een gastcollege bij LUC getiteld: ‘International criminal justice; A view from the Bench’.

In this thesis, bioorthogonal chemistry is combined with correlative light-electron microscopy to selectively label and study pathogenic intracellular bacteria within the host immune cell.

Promotie

Het Netwerk antieke wereld (Ancient Worlds Network) bestaat uit medewerkers en masterstudenten binnen het LIAS die onderzoek doen naar de antieke wereld in het Middellandse Zeegebied en het Nabije-Oosten.

Promotor: Prof.dr. H.S. Overkleeft

The key purpose of this project is to study tautological relations on the level of closed differential forms or even integral cochains (i.e. we don't take classes in cohomology).

When observing star-forming galaxies, we are not only seeing stellar light, but we also see how this interacts with galactic gas and dust. This thesis contains studies of the stellar, nebular and dust properties of low mass star-forming galaxies.

We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.

The ultimate goal of cosmologists is to find a cosmological model able to explain the current observational data.

Promotor: Bas Edixhoven, Promotor: Qing Liu

This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.

We developed the bitterling as a unique, well-studied model organism in the area of the evolutionary ecology of brood parasitism. The bitterling-mussel relationship, interspecific mussel host preference, and mussel gill structure are studied in detail, to help understand the developmental adaptation…

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.

This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.

Neurodegenerative diseases, including Parkinson’s disease (PD), are increasing in prevalence due to the aging population. Despite extensive study, these diseases are still not fully understood and the lack of personalised treatment options that can target the cause of the diseases, rather than the symptoms,…

The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.

Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov

Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.

The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Prof.dr. A.H. Meijer

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.

In 2005 en 2015 heeft de Leiden University Academy of Creative and Performing Arts twee eredoctoraten toegekend.

In this work, we investigate the minute circular dichroism effects of single nanoparticles.To this aim, we apply photothermal imaging with a polarization-modulated heating beam.

Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.

Dark matter is one of the biggest mysteries of the Universe. Its properties cannot be explained with the known laws of physics and elementary particles.

Promotores: Prof.dr. H.J.M. de Groot, Prof.dr. J. Matysik (Universitaet Leipzig)

Real-life processes are characterized by dynamics involving time. Examples are walking, sleeping, disease progress in medical treatment, and events in a workflow.

Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.

Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.

Large parts of the research described in this Thesis aims at the development of oligopeptide-masked toxins and their in situ immunoproteasome-mediated activation.

In this thesis, a system pharmacology approach, integrating metabolomics, pharmacology and chemical biology, was applied to understand and modulate the endocannabinoid system across different model systems (cells, zebrafish, mice and humans).

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

My PhD project studies how the temporally sequential Hox gene expression is regulated during head-tail patterning of the frog embryo.

Why do black holes emit thermal radiation? And how does a closed quantum system thermalize?