884 zoekresultaten voor “were en regelgeving” in de Publieke website
-
Caging ruthenium complexes with non-toxic ligands for photoactivated chemotherapy
The main goal of the research described in this thesis was the development of new photoactivated chemotherapy (PACT) ruthenium(II) complexes bearing a non-toxic photolabile ligand.
-
Molecular and Nano-Engineering with Iron, Ruthenium and Carbon: Hybrid structures for Sensing
Metal complexes and 2D materials like graphene were combined to produce structures that can function as sensors.
-
Vamping the Stage: Female Voices of Asian Modernities
Announcement of the publication of Vamping the Stage: Female Voices of Asian Modernities, the first book-length study of women, modernity, and popular music in Asia (University of Hawai'i Press, 2017).
-
Contributions to the phylogeny of the haplolepideous mosses
The haplolepideous mosses (Dicranidae) comprise about 4000 species distributed over a wide range of habitats, with great gametophytic and sporophytic morphological variation. Their monophyly is well supported by the results of several molecular phylogenetic studies, which shed light on their relationships…
-
Development of nanoparticulate adjuvants based on aluminium salts
The aim of this thesis was to develop aluminium salt-based nanoparticles that may ultimately be used as adjuvant in human vaccines.
-
The quantification of growth hormone secretion : application of model-informed drug development in acromegaly
Growth hormone profiles are pulsatile and highly variable between individuals, limiting the implementation of mathemathical models to quantify an individual's secretion.
-
Gerrit-Jan Zwenne over de Sleepwet en het referendum
Bijna dertig hoogleraren, waaronder Zwenne, ondertekenden een brief aan de Tweede Kamer over de gebreken in de Sleepwet. Daar is te weinig mee gebeurd, vinden zij. Maar een referendum maakt de situatie nóg slechter.
-
A Model Membrane Approach to Elucidate the Molecular Organization in the Skin Barrier
Promotor: J. A. Bouwstra
-
Patterns of coral species richness and reef connectivity in Malaysia
Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema
-
Applying data mining in telecommunications
This thesis applies data mining in commercial settings in the telecommunications industry.
-
Comparative biology of common and grey seals along the Dutch coast : stranding, disease, rehabilitation and conservation
Promotores: H.A. Udo De Haes, P.M. Brakefield
-
Early Dutch Radio Astronomy (1940-1970)
Promotores: F.H. van Lunteren, F.P. Israel
-
Dosing considerations for preterm neonates: from pharmacometrics to clinical practice
Prematurely born neonates require, amongst others, pharmaceutical therapy. Dosing guidelines for these therapies are often based on data from term born neonates or older infants, while these are not necessarily similar to prematurely born neonates.
-
Copper trispyrazolylborate complexes for ethene detection
Promotor: E. Bouwman, Co-Promotor: S. Bonnet
-
Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
-
Monitoring Alzheimer's disease in transgenic mice with ultra high field magnetic resonance imaging
Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia
-
Linking soil microbial community dynamics to N2O emission after bioenergy residue amendments
Vinasse is a major by-product generated by the sugarcane biofuel industry. It is a source of microbes, nutrients and organic matter and often it is recycled as fertilizer.
-
Human-wildlife Interactions in the Western Terai of Nepal
Large carnivores and humans, along with their livestock, have co-existed for thousands of years. However, human population growth and an increase in economic activities are modifying the landscape for large carnivores and their prey.
-
The evolution of chemical diversity in plants : pyrrolizidine alkaloids and cytochrome P450s in Jacobaea
Plants produce an astonishing variety of secondary metabolites (SMs) which are thought to play vital roles in the fitness of plants through ecological interactions.
-
Potential interference of fungal endophytes in Vanilla planifolia on vanilla flavor compounds biosynthesis
Natural vanilla flavor is one of the most important in the world. However, the cost of this flavor is expensive. Production of this flavor by alternative methods, could reduce the cost.
-
The impact of sustainable forest management on plant and bird diversity in East Kalimantan, Indonesia
Promotor: G.R. de Snoo, Co-promotor: H.H. de Iongh, C.J.M. Musters
-
SFA of PVC in Sweden
In this study the flows of PVC and its additives through the Swedish Society were followed from the cradle to the grave (from production to waste treatment).
-
Stellar radio beacons for Galactic astrometry
A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.
-
Terrestrial field trials for side-effects of pesticides
The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…
-
Cheating belowground interactions
Mycoheterotrophy is a particular mode of life in which plants obtain carbohydrates from their associated fungal partners, instead of by using photosynthesis.
-
Quantification in untargeted mass spectrometry-based metabolomics
Promotor: T. Hankemeier, Co-promotor: T.H. Reijmers
-
Towards understanding the toxicity of copper nanoparticles in aquatic ecosystems
Promotores: Prof.dr. W.J.G.M. Peijnenburg & Dr. M.G. Vijver
-
Soil and crop management options to improve nitrogen cycling on dairy farms on peat soil
The main research question of this thesis was: Can nitrogen cycling on dairy farms on peat soil in the Dutch Green Heart area be improved by adapting management to the nitrogen supply from soil and by using other grassland species and crops without affecting milk production?
-
Applications of Natural Deep Eutectic Solvents to Extraction and Preservation of Biomolecules
The recently introduced nature-originated deep eutectic solvents, so-called natural deep eutectic solvents (NADES) are considered as truly green solvents, which composed of natural ingredients found abundantly in organisms.
-
Discovery and development of inhibitors selective for human constitutive proteasome and immunoproteasome active sites
This thesis describes the design and development of subunit‐selective inhibitors of particular catalytically active subunits of human constitutive proteasomes and immunoproteasomes.
-
Mechanistic studies of the water oxidation reaction with molecular iron catalysts
In this dissertation iron-based homogeneous catalysts were synthesized, characterized and investigated for water oxidation activity.
-
Effects of glufosinate-ammonium on off crop vegetation
Description of Effects of glufosinate-ammonium on off crop vegetation.
-
George Orwell: Such, such were the joys
Lezing, Studium Generale
-
Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination
CONCLUSION: This study demonstrates that human macrophages can be induced to exert direct anti-tumor activity against osteosarcoma cells. Our observation that the induction of macrophage anti-tumor activity by L-MTP-PE required IFN-gamma may be of relevance for the optimization of L-MTP-PE therapy in…
-
Studies on the Pathogenesis of Chronic Kidney Disease
In this thesis, two potential therapeutic targets for diabetic nephropathy were dentified and investigated. First, we show that glomerular clusterin is upregulated in diabetic nephropathy and demonstrated that recombinant clusterin protein can protect the podocytes against oxidative stress in vitro.…
-
Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
-
The structure of the cytochrome P450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography
Promotor: Prof.dr. M. Ubbink
-
Effects of pesticides on aquatic macrofauna in the field
Promotores: W.J.G.M. Peijnenburg, G.R. de Snoo, Co-promotor: M.G. Vijver
-
Integrated Chain Management in the Province of Limburg
The cases of building materials, automobility, mushrooms and plastics.
-
The World of Water
The International Course on Water Use and Management in Cagayan Valley The Philippines (2011-2015)
-
Conductance and gating effects at sputtered oxide interfaces
This thesis explores interfacial conductance and electric field-effects in LaAlO3/SrTiO3 heterostructures.
-
Pesticides Atlas, Pilot Study
Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.
-
Illuminating N-acylethanolamine biosynthesis with new chemical tools
In this thesis, the discovery and optimization is described of chemical tools to study the N-acylethanolamine (NAE) biosynthetic pathway.
-
Systematics, Epidermal defense and Bioprospecting of Wild Orchids
This thesis presents the systematics, epidermal defense, and bioprospecting of wild orchids.
-
Growth and Transport properties of (Rare Earth)TiO3 / SrTiO3 interfaces
This thesis presents the results of a study on the interfaces of insulating oxides with and without the insertion of a magnetic layer.
-
Understanding functional dynamics and conformational stability of beta-glycosidases
Due to their central physiological roles in living organisms, retaining beta-glycosidases have been the subject of tremendous research efforts to examine their structure/function relation using numerous biophysical and biochemical approaches.
-
De verzamelwoede van Martinus van Marum (1750-1837) en de ouderdom van de aarde
Promotor: F.J. van Lunteren, E. Jorin
-
Towards controlled microneedle-mediated intradermal immunization
Traditionally, vaccines are administered intramuscularly using conventional hypodermic needles, which cause pain and distress. Microneedles are very short needles (smaller than 1 mm) that are practically invisible to the naked eye.
-
Evolution and development of orchid flowers and fruits
To gain more insight into the evolutionary development of orchid flowers and fruits, the orchid species Erycina pusilla was studied. The evolutionary origin of the median petaloid sepal, the callus on the labellum, and the stelidia was studied.
-
Kutsal Yesilkagit
Faculteit Governance and Global Affairs