De master Asian Studies van de Universiteit Leiden is een hoogwaardige opleiding bij één van de meest vooraanstaande centra voor Aziëstudies in Europa.

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.

De Tweede Kamerverkiezingen die staan gepland voor maart 2017 zullen resulteren in een versnipperd parlement en een lastige kabinetsformatie, aldus de politicoloog Hans Vollaard (Universiteit Leiden) in een bijdrage aan het EUROPP-blog.

Cyclic peptides are investigated as a platform to induce different orientations between various ligands.

Atherosclerosis is the most important underlying process that drives cardiovascular disease, and is characterized by an accumulation of cholesterol which triggers an inflammatory response in the vessel wall.

Cardiovascular syndromes are the major cause of death in Western societies.

How can we quantify the density of species within a community through environmental DNA concentrations?

Trigonostemon Blume is a plant genus in the family Euphorbiaceae comprising 59 species.

This thesis has described novel synthetic methods to produce a variety of (glyco)peptides and their application in the study of various immunological processes.

Koreastudies in Leiden, Korean studies, Japanese studies, Chinese Studies, Asian Studies, South and Southeast Asian Studies, International Studies, Film en Literatuurwetenschap

Promotor: T. H. Oosterkamp

This Thesis describes the design, synthesis and evaluation as glycoprocessing enzyme inhibitors of focused libraries of iminosugars.

Streptomyces are bacteria abundant in soil that participate in diverse and complex interactions. These bacteria are the main producers of the antibiotics we currently use in the clinic.

Glucocorticoids are potent anti-inflammatory drugs widely used clinically to treat various inflammatory and immune conditions. However, two main clinical problems limit their use. GCs trigger severe side effects and they induce acquired glucocorticoid resistance, especially during chronic systemic treatment…

In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.

Geesteswetenschappen, Institute for Area Studies, Chinese Studies

In this dissertation, the synthesis and characterization of a series of iron complexes based on different ligand platforms are described.

Sinds de United Nations Group of Governmental Experts on the Developments in the Field of Information and Telecommunications in the Context of International Security (UN GGE) elf aanbevelingen heeft gedaan over verantwoordelijk staatsgedrag omtrent cyberspace is er een discussie gaande over internationale…

Op 9 april 2019 verdedigde Yudan Tan haar proefschrift 'The Rome Statute as Evidence of Customary International Law'. Het promotieonderzoek is begeleid door promotor prof. dr. W.A. Schabas.

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Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

One of the most important puzzles in modern astrophysics is the nature of dark matter.

Promotor: Prof.dr. H.A.G. Wijshoff

Er zijn wereldwijd vele open (leer)materialen beschikbaar, maar deze worden nog niet of zeer beperkt gebruikt in het onderwijs.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Op 3 april promoveert Sebastiaan van der Lubben. Het Leiden University Centre for Linguistics feliciteert Sebastiaan!

In-use stocks of products can be considered as intermediaries between human needs and the physical world.

In some condensed matter systems, such as the surface of a 3D topological insulator, the electrons are effectively massless and we must necessarily use the massless Dirac equation to describe them.

Promotor: J. Aarts

Security is key to survival for any living organism: life is full of perils and threats, both physically, environmentally, and societally. Security challenges such as terrorism, natural disasters, and cybercrime rank among the most pressing issues of our time, affecting the security and safety of millions…

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

Promotor: J. Kuiper

Promotores: F.H.J. Redig, W.T.F. den Hollander

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

Studievoorlichting

Studievoorlichting

Studievoorlichting

A sustainable resource management is an essential aspect to satisfy the current human needs without compromising the needs of future generations.

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Promotor: Prof.dr. B. van de Water, Co-promotores: L.T.M. van der Ven, A.S. Kienhuis

Acute cardiovascular clinical events such as myocardial infarction and cerebral stroke represent the major cause of death in Western societies. These pathologies are primarily resulting from atherosclerosis, a progressive condition characterized by the accumulation of lipids, immune cells, and fibrous…

Promotores: Prof.dr. H.S. Overkleeft, Prof.dr. G.A. van der Marel

Synthetic hydrogels that mimic the natural extracellular matrix in the biophysical and biochemical cues it provides to cells are in high demand, however the cell phenotypes as they are observed in vivo in numerous cases have yet to be attained.

In order to be able to develop effective medicine and treatments to prevent or cure autoimmune diseases or cancer we need to understand the mechanisms how they arise and what drives their course.Unravelling the fundamental molecular mechanisms influencing the onset and course of diseases such as allergies,…

An interdisciplinary collection of the best international scholarship on Muslim youth.

How can we, together international experts, define future needs of R+D contributions for innovations in the field of risk-based management of chemicals and products in a global perspective using alternative testing strategies to minimize animal tests?