Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf

Fundamental understanding of molecular reactions on metal surfaces is important for improving heterogeneous catalysis.

Laboratory, observation and modeling work on the dissociation of polycyclic aromatic hydrocarbons in interstellar environments and the formation of new molecular species through the fragmentation process.

The space between the stars isn't simply a void; it also contains substances such as methanol and carbon dioxide. So far, chemical theories have been unable to explain how these substances originate under circumstances that should make it impossible. Fedor Goumans has been awarded a Veni subsidy to…

This thesis is an experimental study of the UV irradiation of the interstellar ice analogues, relevant for the different stages of the star and planet formation sequence.

Dit jaar start de Leidse microbioloog Arthur Ram met onderzoek om op grote schaal nuttige enzymen te produceren. Ram ontvangt een NWO-beurs voor het project dat toepassingen heeft in de industriële biotechnologie en voedingsindustrie.

De American Society of Pharmacognosy (ASP) heeft de Varro E. Tyler prijs toegekend aan Rob Verpoorte, voor zijn uitstekende bijdragen aan de wetenschap van de natuur als bron van geneesmiddelen.

This thesis revolves around the electronic spectroscopy of molecules in the laboratory and the search for the carriers of the diffuse interstellar bands (DIBs).

Promotor: Prof.dr. H.L.V. Linnartz

Catalysis is of extreme relevance in the production of everyday materials and plays a central role in many aspects of our life.

A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.

The adsorption of D2 and CO2 on catalyst surfaces is studied using a molecular beam in ultra-high vacuum.

Promotor: Prof.dr. E. Smets, M. Stech

Promotor: Prof.dr. E.F. Smets, Co-Promotor: L.W. Chatrou

In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.

Large areas of space are filled by molecular clouds that consist of gas and dust grains that are the remnants of dead stars. When these clouds start collapsing, the decreasing temperature and increasing density cause gas particles to start accreting onto dust grain surfaces.

Promotor: Prof.dr. H.P. Spaink, Co-promotor: Dr. B.E. Snaar

Filamentous Actinobacteria, such as Streptomyces, produce a plethora of chemically diverse bioactive metabolites that have found applications across medicine, agriculture and biotechnology.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

The long-held desire - to link structure directly to function and to explain molecular mechanisms based on basic chemical or physical principles - is finally coming closer, satisfying not only our scientific curiosity but also offering new solutions to the many challenges in the field of health, energy…

Voor het eerst hebben onderzoekers uit Utrecht, Leiden, Amsterdam, Liverpool en Maastricht mini-orgaantjes van slangengifklieren in het lab gekweekt. De groepjes cellen kunnen gifmoleculen produceren. Dit is een belangrijke stap om slangenbeten beter te behandelen. Publicatie in toptijdschrift Cell…

Promotor: F.P. Israel, Co-Promoter: R. Meijerink

This thesis advance our understanding and the application of molecular catalysts relevant to the reduction of oxygen as well as reduction of nitrite.

Mechanical forces are known to play an important role in bacterial colonies. In this dissertation, we study the self-organization at various stages of growing bacterial colonies, and focus on the mechanical effects of cell growth.

What is the population size/structure and distribution of tiger and leopard inside the Bardia National Park (BNP) compared with the population outside? What is the movement and home range and conflict pattern in time and space of tigers and leopards inside the BNP compared with outside? What constitutes…

Het stofje galantamine uit bloembollen kan symptomen van Alzheimer bestrijden. Nadeem Akram onderzocht hoe narcissen dit natuurlijke medicijn optimaal kunnen produceren. Promotie op 24 juni.

Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.

Actinobacteria are Gram-positive bacteria that have a complex multicellular life cycle and are well known for their ability to produce a wide range of bioactive natural products (NPs).

Heterogeneous catalyzed processes are highly significant to the chemical industry. Dissociative chemisorption (DC) of molecules on surfaces is always considered as a step with a high degree of rate control for heterogeneous catalysis.

This thesis describes a study from both a theoreticaL and an experimental point of view.

Promotor: H.V.J. Linnartz

Hybrid zones occur where two species meet and produce offspring (hybrids). Typically, hybrids show a considerable reduction in fitness. In this thesis two hybrid zones are treated.

The formation and evolution of galaxies is fundamentally driven by the formation of new stars out of cold gas.

Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.

Promotor: Prof.dr. E. Bouwman, Co-Promotor: S. Bonnet

Resistentie tegen antibiotica heeft ertoe geleid dat de huidige middelen om bacteriën te bestrijden, dat niet meer zo goed kunnen als vroeger. Vandaag de dag overlijden er mensen aan bacteriële infecties die vijftig jaar geleden wel behandeld hadden kunnen worden.

Promotor: Prof.dr. E. F. van Dishoeck

The work in this thesis demonstrates how to obtain an atomic-scale picture of a diverse set of complex surface structures observed using STM, under disparate conditions.

Several techniques are explored for going beyond the born-oppenheimer static surface model for molecule-surface reactions.

Studievoorlichting

This thesis presents pioneering work on the panchromatic emission of some of the most luminous galaxies in the early Universe: star forming galaxies and active galactic nuclei.

Animal diet studies are critical for understanding ecological processes such as trophic interactions, energy flow, and nutrient cycling. By examining what animals consume, ecologists gain insights into species specialization, predator-prey relationships, and ecosystem management.

De natuur is een onuitputtelijke inspiratiebron voor de wetenschappers van het Instituut Biologie Leiden (IBL). Vanuit het streven naar fundamenteel begrip van de natuur zoeken zij naar oplossingen op het gebied van gezondheid en behoud van de biodiversiteit. Het thema van het instituut is ‘Harnessing…

Actinobacteria are well known for the production of bioactive natural products, many of which have applications in the fields of human, animal and plant health. Subject of this thesis are the anthracyclines, glycosylated aromatic polyketides with potent anticancer activity.

Metals surfaces form a group of effective catalysts for the reaction of small molecules such as hydrogen (H2).

Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet