Promotor: Prof.dr. S. Portegies Zwart

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

Triple-negative breast cancer (TNBC) constitutes a small subtype (~15%) of breast cancer, but causes the majority of breast cancer-related deaths.

A new environmental accounting framework using externality data and input-output tools for policy analysis.

Vast, often populated, areas in dryland ecosystems face the dangers of desertification.

Promotor: K.H. Kuijken

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Promotor: Prof.dr. H.L.V. Linnartz

In this thesis, we have studied cell images from two types of cells, including pollen grains and the immune cells, neutrophils. These images are captured using a bright field microscope and a confocal microscope.

The ReCiPe methodology for Life Cycle Impact Assessment (LCIA).

Promotor: H.P. Spaink, A.H. Meijer Co-promotor: R. Marin-Juez

Promotor: T.H. Oosterkamp

Understanding the formation and evolution of planetary systems is one of the most fundamental challenges in astronomy. To directly image and study young exoplanets and the circumstellar disks they form from, dedicated high-contrast imaging instruments are built.

Promotor: P. J. J. Hooykaas, Co-promotor: R. Offringa

This thesis covers various applications of topology in condensed matter physics and quantum information.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Promotor: K.J. Batenburg, Co-promotor: A.W. van der Vaart, B. de Smit

Atherosclerosis is the main underlying pathology of cardiovascular disease. Atherosclerosis is caused by an immune response which is directed against (modified) lipoproteins which accumulate in the vessel wall.

Chemical-induced organ toxicity is a major concern in the development and use of chemicals, including drugs, pesticides, industrial chemicals and cosmetics. In the last decades, the onset and progression of chemical-induced organ toxicity has been linked amongst others to perturbation of mitochondri…

Promotor: Prof.dr. E Gittenberger, Co-Promotores: C.H.J.M. Fransen, B.W. Hoeksema

Promotores: G.W. Canters, T.J. Aartsma

In this thesis, the role of plant-mediated soil legacy effects in shaping aboveground plant-insect interactions was investigated.

Promotores: F.H. van Lunteren, F.P. Israel

Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.

This thesis mainly focuses on cross-modal retrieval and single-modal image retrieval via deep learning methods, i.e. by using deep convolutional neural networks.

Surface plasmons (SPs) are surface waves at the interface between a dielectric and a good metal, and are formed by the interaction between light and the free electrons at the metal-dielectric interface. They provide strong field confinement for optical fields, opening new possibilities for enhanced…

Promotor: J.W. van Holten

This thesis investigates the contribution of quantum computers to machine learning, a field called Quantum Machine Learning. Quantum Machine Learning promises innovative perspectives and methods for solving complex problems in machine learning, leveraging the unique capabilities of quantum computers…

Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…

Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.

Promotor: Prof.dr. J. Kuiper

This thesis describes the use of bioorthogonal proteins in immunological settings. It provides an introduction towards the field of protein modification, which was used throughout the thesis for the expression of proteins containing unnatural amino acids.

Promotores: P. Stevenhagen, L. van Geemen Co-promotor: R.M. van Luijk

Promotor: A. Kros

Galaxies are environments where gas coalesces, cools, and is converted into stars. However, it remains unclear the exact mechanisms through which galaxies acquire, redistribute and lose their gas.

The research aims to explore the evolutionary adaptability of enzymes and the impact of temperature on protein evolution pathways, using M. tuberculosis β-lactamase BlaC as the object of study. Enzymes inherently embody a delicate balance between activity and stability, and the acquisition of new enzymatic…

Solute carrier (SLC) transporters are a large and diverse class of relatively understudied transmembrane proteins.

With tomography it is possible to reconstruct the interior of an object without destroying.

This interdisciplinary study focuses on (trans)national ethnic and popular networks, combining historical-ethnographic and computational methods to understand the ‘workings’ of networked conflict interfering in the increasingly violent conflict in the Sahel (Africa) and beyond. The project focuses on…

This Thesis focuses on the design and synthesis of ADP-ribosylated compounds that can be applied in biological studies.

Promotor: C.J. ten Cate

Recentelijk is een Special Issue van de European Journal of Criminology verschenen, die is samengesteld door Marieke Liem, Universitair Docent Criminologie bij het Instituut voor Strafrecht & Criminologie, en William Pridemore.

This thesis studies the geometry of representation varieties and character stacks. These are spaces parametrizing the representations of a finitely generated group, typically the fundamental group of a compact manifold, into an algebraic group G.

Promotores: C. J. ten Cate; M. A. Ainslie. Co-promotor: W. Slabbekoorn

Inactivating mutations in BRCA1 or BRCA2 genes predispose to several types of cancer.

Promotor: M. Danhof Co-promotor: O.E. Della Pasqua

Promotor: H.S. Overkleeft, Co-promotor: M. van der Stelt

De programmagroep Leer- en Gedragsproblemen in het Onderwijs doet onderzoek naar stagnaties die kunnen optreden in de cognitieve ontwikkeling.

Promotor: Prof.dr. E.F. Smets. Co-promotores: B. Gravendeel, F. Pupulin