In this thesis we explore machine and deep learning approaches that address keychallenges in high dimensional problem areas and also in improving accuracy in wellknown problems. In high dimensional contexts, we have focused on computational fluid dynamics (CFD) simulations.

In this thesis, I study the formation of large-scale structure and the physics of particle acceleration at large scales (~Mpc).

The European Council and the European Commission have a similar role in agenda setting. Both place issues on the EU agenda. However, these institutions have distinct designs. They have different political attributes (the European Council has considerably more political authority) and information-processing…

Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.

Op 11 november 2021 verdedigde Evelien Campfens het proefschrift 'Cross-border Claims to Cultural Objects'. Het promotieonderzoek is begeleid door prof.dr. N.J. Schrijver en prof.dr. W.J. Veraart (VU Amsterdam).

Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt

Materials with strongly correlated electrons show some of the most mysterious and exotic phases of quantum matter, such as unconventional superconductivity, quantum criticality and strange metal phase.

In this thesis I highlight the applications of Oxford Nanopore Technologies (ONT) sequencing. This technique is a relatively new approach in the sequencing field, where nanopores are embedded in a membrane, DNA molecules are pulled through nanopores and an electrical current serving as the sequencing…

The parabolic Anderson model (PAM), which is the Cauchy problem for the heat equation with random potential. The PAM is a mathematical model that describes how mass (i.e. matter or energy) flows in a medium in the presence of a field of sources and sinks.

Promotor: Prof.dr. E. Smets, M. Stech

Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea

This thesis focuses on data found in the field of computational drug discovery. New insight can be obtained by applying machine learning in various ways and in a variety of domains. Two studies delved into the application of proteochemometrics (PCM), a machine learning technique that can be used to…

Taking as a point of departure the Italian American community in Boston and its process of collective remembrance surrounding Saint Anthony’s Feast, we addressing the limits and potential of montage.

In this thesis, rational points on K3 surfaces are studied. In the first part of Chapter 1 the Brauer group and the the Brauer-Manin obstruction are introduced.

Wiskunde en Natuurwetenschappen, Leids Instituut voor Onderzoek in de Natuurkunde (LION)

Lezing, Onderdeel van een serie

Het Europese project SUNRISE - ‘zonne-energie voor een circulair economie’, is geselecteerd als één van de zes Coördinatie- en Ondersteuningsacties (CSA) binnen het Horizon 2020-programma van de Europese Commissie. Het project ontvangt een subsidie van 1 miljoen euro en zal de basis leggen voor een…

Met trots kunnen wij meedelen dat het boek ‘Turnaround Management and Bankruptcy’ gepubliceerd is. De editors van dit boek zijn Prof. dr. mr. J.A.A. Adriaanse en Prof. dr. J.I. van der Rest. Beide zijn werkzaam bij de afdeling Bedrijfswetenschappen van de Faculteit der Rechtsgeleerdheid.

As Leiden Law students, we are now in the digital age, 'where we believe law and technology should go together.' After all, for us, it is important to look beyond trodden paths of established legal knowledge. The books on law and case law surely will not be sufficient for the lawyer of the future. That…

Friday 30 January 2015 were the final presentations of the last course of the Minor Sustainable Development.

This interdisciplinary minor addresses sustainabilty challenges from a systems perspective, and investigates ways to sustain society within planetary boundaries.

New master specialisation: Economics and Governance

In 2012 the Pascal chair of the Faculty of Science of Leiden University, and particular of Leiden Institute of Advanced Computer Science (LIACS), will be held by Prof. Dr. Kyle Gallivan, Department of Mathematics, Florida State University, USA.

Ook dit jaar waren de presentaties op het jaarlijkse slotevenement van de PRE-Classes van hoog niveau! Bleda Dühring, de keynote speaker, liet zien hoe een archeologische opgraving over het Assyrische rijk nog heel relevant is vandaag de dag. De Pre-Classers vertelden enthousiast over uiteenlopende…

De Universiteit Leiden zet zich ervoor in dat haar laboratoria een accreditatie krijgen van het Laboratory Efficiency Assessment Framework (LEAF)

Om katalysatoren te bouwen die ontelbaar vaak brandstoffen uit CO2 kunnen produceren, moeten we nog veel meer te weten komen over de werking van katalyse. Irene Groot verricht baanbrekend onderzoek naar katalyse op atomair niveau.

Ben jij geinteresseerd om Bede Sheppard, Human Rights Watch’s Deputy Director of the Children’s Rights Department te ontmoeten? Bede zal donderdag 26 mei voor het #WatchOurSchools evenement in het Auditorium van Anna van Bueren zijn, en wij geven hierbij onze studenten de kans om hem van tevoren te…

Lezing

The main aim of this project is to reveal and unravel the invisible histories of the UN, transcending the dominant Western perspective to recover the historical agency of Global South actors. The research will investigate how the UN has both facilitated and limited their role in shaping global order…

Promotie

Promotie

Working Group

Een internationaal team van astronomen, onder wie drie Leidse sterrenkundigen, hebben een sterrenstelsel ontdekt op een recordafstand van 13,4 miljard lichtjaar. Het stelsel, dat in de richting van het sterrenbeeld Grote Beer staat, is uitzonderlijk helder, waardoor het mogelijk was het op deze recordafstand…

Lees hier de publicaties die over het Erfgoed Gezocht project zijn verschenen.

A neurocognitive investigation of the development of social performance monitoring in youth growing up in stressful versus non-stressful environments

This dissertation presents a new perspective on the life, work and character of the Dutch physical chemist Jacobus Henricus van ’t Hoff, first recipient of the Nobel Prize in Chemistry, and one of the most important and colourful scientists in Dutch history. The image of Van ’t Hoff that emerges from…

A recent study on reintroduced tigers in Panna Tiger Reserve in India reveals that risks from tigers increased more because of human behaviour and people's livestock husbandry practices.

CML-IA is a database that contains characterisation factors for life cycle impact assessment (LCIA) and is easily read by the CMLCA software program.

Investigating the contribution of interpreters, informants, hunters and guides in the making of colonial scientific knowledge.

Duurzaam geproduceerd voedsel beperkt de CO2-emissie bij de productie en bevordert de economie van de regio. De universiteit werkt aan het vergroten van het aandeel biologische, fairtrade-, vegetarische en veganistische producten in de universitaire restaurants.

What performance criteria does a new technology have to fulfill in order to be added to the list of future energy options and what constraints exist in terms of broad market penetration?

Leids onderzoek draagt bij aan de kennis over duurzaamheidsthema’s. Dit is noodzakelijk om aan gezamenlijke oplossingen te werken voor bijvoorbeeld de huidige klimaat- en grondstoffenproblematiek.

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Ferritin is a spherical metalloprotein, capable of storing and releasing iron in a controllable way. It is composed of a protein shell of about 12 nm and within its cavity, iron is stored in a mineral form.

Death in all types of melanomas is generally caused by metastasis. Uveal melanoma (UM) is the most common intraocular melanoma, there are currently no (patient-derived) animal models that faithfully recapitulate metastatic dissemination of UM.

The lipid membrane is a basic structural component of all living cells. Embedded in this nanometer-thin barrier, membrane proteins shape the membrane and at the same time respond to the shape of the membrane.

Consequences for sediment stability and seston trapping

The subject of this thesis, ‘Approach to Markov Operators on Spaces of Measures by Means of Equicontinuity’, combines an analytical and probabilistic approach to Markov operators.

The deeper understanding of an organism's pathology is important for developing treatments. Over centuries of systematic research, clinical researchers have demonstrated that the more information they acquire about the cellular properties and their organisation in the tissue, the better they can understand…