Microbial rhodopsins are photosensitive pigments implemented in the growth and adaptation of a large population of microorganisms.

Bacteria often experience external challenges, such as changes in environmental conditions or attacks by bacteriophages.

The main focus of the thesis is the discovery and development of novel inhibitors of bacterial metallo-β-lactamases (MBLs).

Promotor: J. van der Greef; Co-promotor: E. van Wijk, M. Wang

Vastgoed heeft een handige Q&A met veelgestelde vragen over de nieuwe Humanities Campus opgesteld voor met name de omwonenden van het Witte Singel-Doelencomplex. Niet alle berichtgeving in de media is juist, daarom plaatsen we de Q&A ook voor alle medewerkers. Wil je weten hoe het zit met de gebouwen…

De letter M is ontstaan uit een tekeningetje van kabbelend water. Dat leert het kinderboek ‘A is van Os’ waaraan de Leidse egyptoloog Ben Haring een belangrijk aandeel had. In juni kwam het uit.

Het VICI onderzoeksproject Citizenship Discourses in the Early Middle Ages, onder leiding van Els Rose (Universiteit Utrecht), heeft een nieuw boek uitgebracht: Els Rose, Robert Flierman en Merel de Bruin-van de Beek, red., City, Citizen, Citizenship, 400–1500. A Comparative Approach (Londen: Palgrave-Macmillan,…

Het boek Turkey. A Modern History van Prof.dr. Erik-Jan Zürcher, hoogleraar Turkish Studies, is nu in negen talen gepubliceerd. Deze maand verschenen de Arabische en Poolse vertalingen.

Optimally solving real-world expensive Black-Box Optimization (BBO) problems w.r.t. real-world constraints, such as wall-clock time and computational costs, is extremely difficult and tedious.

How should jurisdictions, both on the national and on the supra-national level, handle the interaction between public and private law where it regards the regulation of financial markets?

In this thesis, time-lapse fluorescent microscopy plays a pivotal role in investigating functional materials within living cells as well as the migratory behaviour of neural progenitor cells.

Discover the master program Health, Ageing and Scoiety at Leiden University and contribute to a future proof health care system. Read more.

In this thesis, I study 1) metabolic alterations in tuberculosis related to wasting syndrome in human patients as well as in rodent and fish animal models. 2) effects of the mutation of the leptin gene on cachexia and diabetes in rodent and zebrafish animal models.

Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.

Op 1 juni 2022 verdedigde Tom Herrenberg het proefschrift 'Prosecutorial Discretion in International Criminal Justice'. Het promotieonderzoek is begeleid door prof.dr. P.B. Cliteur en prof.dr. B.R. Rijpkema.

Evolution acts via mutations in amino acid sequences. Substitution of essential amino acids leads to a nonfunctional protein. l.

With the emergence of online social networks (OSNs), the way people create and share information has changed, which becomes faster and broader than traditional social media.

The interest of this thesis lies in spin transport in normal metals and superconducting half-metallic junctions.

Promotor: E. Bouwman, Co-Promotor: S. Bonnet

Subproject of the ERC project 'Challenging the Liberal World Order from Within: The Invisible History of the United Nations and the Global South'.

Prof.dr. P. Stevenhagen, Prof.dr. K. Belabas (Universite Bordeaux I)

Na het ontvangen van je diploma van LUC, kun je als alumni overal ter wereld heen. Velen die je voor zijn gegaan hebben ervoor gekozen om een master als vervolgopleiding te doen. Sommigen beginnen meteen aan hun professionele carrière of volgen een PhD. Door de vele academische vakgebieden die op LUC…

Wetlands provide many ecosystem goods and services which include fish production. The sustainability of small-scale fisheries (SSF) has received considerable attention in recent years because fish is one of the major sources of animal protein to a considerable fraction of the global population which…

Op 16 december 2021 verdedigde Lisanne van Houten het proefschrift 'Flexing the Slot Regime'. Het promotieonderzoek is begeleid door prof.dr. P. Mendes de Leon en prof. L. Pierallini (Luiss University Of Rome).

What is the current relevance of the ethics of counterterrorism and what is the added value of ethics support within the practice of counterterrorism?

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

Promotor: Prof.dr. G.P. van Wezel

Promotor: M.T.M. Koper, Co-promotor: L. Juurlink

In this work, we attempt to answer the question:

Lipid formulations have demonstrated strong potential for nucleic acid delivery,particularly with the success of COVID-19 vaccines. Despite these advances, manyaspects of lipid formulations remain unclear.

Antibiotic-resistant bacteria pose a major health threat. Addressing this challenge requires among others the development of new antibacterial compounds. The research described in this thesis focuses on discovering novel antibiotics from soil bacteria, specifically Streptomyces and Paenibacillus.Despite…

By training with virtual opponents known as computer generated forces (CGFs), trainee fighter pilots can build the experience necessary for air combat operations, at a fraction of the cost of training with real aircraft.

Promotores: Prof.dr. J. Aarts, Prof.dr. J.M. van Ruitenbeek

In times of hardships or crisis, local people know how to deal with it using their resourcefulness. Although efforts are sometimes made by the government to help them, they are fully aware that community support is at least equally important.

A new publication on changes in the relationship between news and their public in Chile

Natural history collections provide invaluable sources for researchers with different disciplinary backgrounds, aspiring to study the geographical distribution of flora and fauna across the globe as well as other evolutionary processes.

Promotores: Wim Jiskoot; Ferry Ossendorp

Promotor: P.J.J. Hooykaas, Co-Promotor: E.J. van der Zaal

Promotor: E. Gittenberger, Co-promotor: B.W. Hoeksema

This dissertation is about Bayesian learning from data. How can humans and computers learn from data?

A modern ship design process is subject to a wide variety of constraints such as safety constraints, regulations, and physical constraints.

This thesis describes the role of pollution, specifically neonicotinoid insecticides, as an actor of the ongoing biodiversity decline.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Hydrogen fuel cells are expected to be pivotal in the energetic transition towards renewable energy sources such as solar and wind power. However, their industrial scalability is severely hindered by the high cost and degradation rate of platinum catalysts, one of their key components. Addressing this…

Agrobacterium tumefaciens, a gram-negative plant pathogen belonging to the family Rhizobiaceae, is the causative agent of crown gall disease, which can affect many plant species including agronomically important ones.

Green hydrogen is produced via a process called water electrolysis. During electrolysis water is split into oxygen and hydrogen.

Promotor: Jelle S. Kaastra Co-promotor: Jelle de Plaa

Over the last decades, aviation safety has improved strongly. As a downside, airline pilots do not have as many opportunities to develop through experience the competencies that they need in critical situations.