527 zoekresultaten voor “play and media” in de Publieke website
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Gibbs Processes and Applications
Gibbs measures, as used in Statistical Mechanics, have a definition that is remarkably similar to the definition ofg-measures, used in dynamical systems.
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Shining Light on Interstellar Matter
Promotor: H.V.J. Linnartz
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Dormancy in stochastic interacting systems
Organisms often need to adapt more efficiently and devise new strategies for surviving difficult ecological circumstances.
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Optoplasmonic detection of single particles and molecules in motion
Detecting nanoscopic objects plays an important role in nanoscience in particular, in the rapidly growing field of nanobiology. The forebear to modern super-resolution microscopy for single molecule investigation, is fluorescence microscopy.
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Computational modeling of cellular dynamics in tumor cell migration
Epithelial-mesenchymal plasticity (EMP) and tumor cell migration play an important role in cancer progression, and an improved understanding of the mechanisms underlying these concepts is essential for developing new targeted approaches.
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Innate immunity, developmental speed and their trade-offs in two hexapod models
This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.
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Cellular Forces: Adhering, Shaping, Sensing and Dividing
Promotor: Prof.dr. T. Schmidt
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Inhibitors and activity-based probes for β-D-glucuronidases, heparanases and β-L-arabinofuranosidases
Glycosidases (GHs) are enzymes responsible for the degradation of carbohydrates and play many roles in human health and pathophysiology. Often, abnormal levels of glycosidase activity are markedly linked to human pathologies.
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Structural changes in single chromatin fibers induced by tension and torsion
Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort
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Functional characterization and unraveling the Gene Regulatory Networks (GRNs) of HD-Zip transcription factor HB40 (and HB22) in Arabidopsis thaliana
In this Ph.D. thesis, we characterized two novel upstream regulators of JUB1, HB40, and HB22, in Arabidopsis thaliana. In Chapter 2, we described functions of HB40 in modulating growth and development via the regulation of JUB1 and GA inactivation genes GA2OXs.
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The tension between nature conservation and economic valuation of ecosystem services
Promotores: G.R. de Snoo, W.T. de Groot, Co-promotor: C.J.M. Musters
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Cognitive Bias in the Judgment of Business Valuations and Valuators
Op 1 april 2020 verdedigde Marc Broekema zijn proefschrift 'Cognitive Bias in the Judgment of Business Valuations and Valuators'. Het promotieonderzoek is begeleid door promotor prof. dr. J.I. van der Rest.
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Innovation and stasis
The name ‘Jambi flora’ refers to fossil plants found as part of a rock formation from the Early Permian (296 million years old), located in the Jambi Province of Sumatra, Indonesia.
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Omics data integration with genome-scale modelling of dopaminergic neuronal metabolism
Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.
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The electrode-electrolyte interface in CO2 reduction and H2 evolution: a multiscale approach
Electrocatalysis allows for storing electricity or converting it into chemical bonds, producing chemical building blocks and fuels using renewable resources.
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Development of kinase inhibitors and activity-based probes
Promotor: H.S. Overkleeft, J. Neefjes, Co-promotor: M. van der Stelt
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The role of the Arabidopsis AHL15/REJUVENATOR gene in developmental phase transitions
This thesis describes the functional analysis of the Arabidopsis AHL15 gene.
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The role of the interleukin 12 family in atherosclerosis
Promotor: Johan Kuiper, Co-promotor: Saskia C.A. de Jager
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Understanding protein complex formation: The role of charge distribution in the encounter complex
Protein–protein complexes are formed via transient states called encounter complexes that greatly influence the formation of the stereospecific complex.
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Social network and radical innovation: evidence from the U.S. pharmaceutical and biotechnology industry
Innovation plays an essential role in firms' competitiveness and long-term success. It varies from different types, ranging from run-of-the-mill innovation that brings incremental changes to existing technologies to radical innovation that breaks from existing trajectories.
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Disrupting the transcriptional machinery to combat triple-negative breast cancer
Triple-negative breast cancer (TNBC) is a subtype of breast cancer characterized by limited treatment options and unfavorable clinical outcomes. Therefore, the research described in this thesis focused on the exploration of novel targeted therapies for TNBC.
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Innovative sample preparation and handling strategies for automated and high-throughput metabolomics
Metabolomics has the potential to play a pivotal role in understanding disease onset and progression, and ultimately personalized treatments. One of its major challenges is its large-scale implementation, which is necessary to deal with the high variability of the metabolome. In this work we have developed…
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into the role of ceramide subclass composition on lipid organization and skin barrier
The lipids in the uppermost layer of the skin, the stratum corneum (SC), play an important role in the skin barrier function. The three main SC lipid classes are ceramides (CER), cholesterol and free fatty acids.
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Affinity-based profiling of the adenosine receptors
The adenosine receptors are proteins that reside in the extracellular membranes of cells. Activation of adenosine receptors plays a role in many physiological and pathological processes, such as immune responses and cancers.
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Fundamental research on the voltammetry of polycrystalline gold
Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.
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Functionalized two-dimensional membranes and materials for solar-to-fuel devices: a multiscale computational approach
In the current global context, there is a pressing need to address sustainable energy supplies to safeguard our Planet and its ecosystems. The choices made by human society have a significant impact on genetic evolution and climate.
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Thiosugars: reactivity, methodology and applications
Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…
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K-pop
Kunst en vrije tijd, Kunst en vrije tijd
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Mattijs Numans
Faculteit Geneeskunde
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Antonius Johannes Rabelink
Faculteit Geneeskunde
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Liwen Meng
Faculteit der Sociale Wetenschappen
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Peter van der Zwan
Faculteit Rechtsgeleerdheid
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Peter de Knijff
Faculteit Geneeskunde
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Nadia Garnefski
Faculteit der Sociale Wetenschappen
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Alies Jansen
Faculteit der Geesteswetenschappen
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Abdourahamane Idrissa Abdoulaye
Afrika-Studiecentrum
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Susan van den Brink
Wiskunde en Natuurwetenschappen
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Granular Flows: Fluidization and Anisotropy
Promotor: Prof.dr. M.L. van Hecke
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Weiyan Low
Faculteit der Sociale Wetenschappen
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Bart Barendregt
Faculteit der Sociale Wetenschappen
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Akrati Saxena
Wiskunde en Natuurwetenschappen
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Federico De Musso
Faculteit der Sociale Wetenschappen
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Random walks in dynamic random environments
Promotor: W.Th.F. den Hollander
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Zheng Li, Promoting Harmony with Conflicts?
In dit proefschrift wordt gekeken naar de produktie en consumptie van het reality-tv-programma ‘Nieuwe Wijze Oom’. Deze show, uitgezonden op het entertainmentkanaal van de provincie Shanghai, draait om mediation in conflicten tussen burgers. ‘Nieuwe Wijze Oom’ is geliefd bij het publiek én bij de autoriteiten.…
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CIRM interviewt Frank den Hollander
Van 2 t/m 6 juni 2014 heeft Prof. dr. Frank den Hollander 2 voordrachten verzorgd tijdens de workshop ‘Recent Models in Random Media’ op het Centre International de Rencontres Mathematiques in Marseille (CIRM), een instituut dat gedurende het hele jaar workshops voor wiskundigen organiseert.
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creatIef, Creatiever, creaTiefst? Onderzoek naar het belang en de werking van creativiteitstraining bij Bachelor ICT-studenten
This dissertation presents the results of the importance of creativity for ICT-students of Dutch universities of applied sciences (in Dutch: hogescholen), and the functioning of training courses that aim to promote creative abilities is highlighted.
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The electrochemical reduction of dioxygen and hydrogen peroxide by molecular copper catalysts
The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…
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AT-HOOK MOTIF NUCLEAR LOCALIZED 15 gene in Arabidopsis meristem activity and longevity
Plant architecture has distinct forms in different plant species, but also within a species the finalarchitecture of a plant is determined by its gradual development and changes therein induced by environmental conditions during the plant’s life cycle.
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The impact of defense hormones on the interaction between plants and the soil microbial community
The soil ecosystem consists of the largest reservoir of biodiversity on Earth.
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Cell-autonomous and host-dependent CXCR4 signaling in cancer metastasis: insights from a zebrafish xenograft model
Promotor: A.H. Meijer, Co-promotor: B.E. Snaar-Jagalska