Promotor: Prof.dr. J.N. Kok, Co-promotor: F.J. Verbeek

Wangyang Fu

Onderzoeksgroepen in het Biological & Soft Matter onderzoeksprogramma ontrafelen de mechanismen in biologische processen en ontwikkelen nieuwe zachte materialen die geïnspireerd zijn door de natuur.

Schneider

Shape and biological function are tightly connected. Physical descriptions are used to connect the shape of a biological system with its function.

This dissertation contains four works during my PhD. Different biomaterials have been designed based on coiled-coil peptides. These biomaterials have a range of applications, inclusing drug delivery, cell sorting to cell-cell fusion.

In deze master specialisatie ligt de focus op het begrijpen van biologische processen in hun natuurlijke context, zoals cellen en weefsels.

How do nanoparticles bioaccumulate and biodistribute in organisms?

Promotores: H. Schiessel, G.T. Barkema

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Description of The Regional Network on the Synergy between the Convention on Biological Diversity and the UN Convention to Combat Desertification.

What is vegetation structure and composition in SFM primary forest, secondary logged over forest (logging FSC certified and logging non certified) in comparison to primary forest? What is avian guild diversity in SFM primary forest, secondary logged over forest (logging FSC certified and logging non…

Met deze subsidie zal prof.dr. Lisa Cheng samen met dr. Jenny Doetjes onderzoek doen naar vraagzinnen in verschillende talen.

This PhD-thesis presents a study on micron-sized particles, so-called colloids. By controlling the chemical and physical properties of these particles, such as the interparticle interaction and the particles’ shape, colloids can act as building blocks that self-assembly into larger structures.

The major and ultimate aim of metabolomics is to obtain an answer to a specific biological or clinical question.

Promotor: Prof.dr. P.G.L Klinkhamer, Co-promotor: K. Vrieling

The emergence of complex diseases resulting from abnormal cell-cell signaling and the spread of infectious diseases caused by pathogens are significant threats to humanity. Unraveling the dynamic mechanisms underlying cell-cell signaling and infectious disease spreading is crucial for effective disease…

LIBC PUBLIEKSDAG 'DAAR ZIT MUZIEK IN' (in Dutch)

LIBC PUBLIEKSDAG 'IMAG(IN)ING THE BUDDHIST BRAIN' (in Dutch)

Parkinson's disease is the second most common neurodegenerative disease in the world. One of its symptoms is the loss of dopaminergic neurons in the substantia nigra pars compacta.

Mechanical interactions between cells and their environment play an important role in many biological processes.

In this thesis, we show how MRFM can usefully contribute to the field of condensed-matter.

Vitamin A or retinol is essential in embryonic development, the visual cycle and the immune system.

Promotor: A. Kros

Biological polymers, including proteins and the genome, undergo folding processes crucial for their proper functioning. Even slight changes in the folding structure of these biopolymers can have significant implications, leading to the development of various pathological conditions, such as neurodegenerative…

Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.

Binnen de computationele taalkunde wordt er gebruik gemaakt van computermethodes om antwoord te krijgen op taalkundige vragen over verscheidene onderwerpen.

This thesis focuses on important life history traits and their trade-offs using two hexapod models. Particularly, the trade-off between immune defense and embryonic developmental speed is a central theme of this study.

Syntactici onderzoeken hoe woorden in de menselijke taal worden gecombineerd tot grotere eenheden (frases en zinnen) en hoe de combinatiemogelijkheden de woordvolgorde en de grammaticale relaties tussen de delen van een zin bepalen.

What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?

Lipid signaling is an essential biological event/process in a plethora of pathophysiological conditions. The underlying idea of this thesis is that many of the roles and the complex interplay of the individual signaling lipids in inflammatory processes and related conditions in health and disease is…

Advanced mass spectrometry of glycosphingolipids takes the central stage in this thesis. Investigations focus on characterization of glycosphingolipid metabolism in health and disease with emphasis to the detection and accurate quantitation of known and so far unknown glycosphingolipids and closely…

Promotor: Prof.dr. J.N. Kok

Carbohydrates, alongside proteins and nucleic acids, constitute a crucial and versatile family of biomolecules present in all life forms. They manifest as monosaccharides, oligosaccharides, and polysaccharides, covalently bonded to proteins and fats. Carbohydrates are integral to plant and arthropod…

Promotor: J.G.E.M. Fraaije, Co-Promotor: A. Kros

Promotor: Prof.dr. T. Hankemeier

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

This work has described synthetic strategies towards well-defined structures resembling capsular polysaccharide (CPS) fragments, CPS mimics, teichoic acid (TA) fragments as well as a third-generation ring-closing tandem metathesis (RCM) linker to better exploit the potential of automated synthesis.

Bacteriophages, or phages for short, are the most abundant biological entity in nature. They shape bacterial communities and are a major driving force in bacterial evolution.