1,307 zoekresultaten voor “evolution and development” in de Publieke website
-
The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
-
Strafrecht & Criminologie
Het Instituut voor Strafrecht & Criminologie houdt zich bezig met onderzoek en onderwijs op respectievelijk het gebied van het straf(proces)recht en de criminologie.
-
Programmastructuur
De masteropleiding Health, Ageing and Society leidt haar studenten op tot academische professionals op het gebied van gezondheid, ouderen en samenleving. Studenten voelen zich na afronding van de opleiding betrokken bij de maatschappij en zijn in staat om een bijdrage te leveren aan oplossingen voor…
-
Selective autophagy in host defense against mycobacterial infection
The effective treatment of tuberculosis (TB) remains a major challenge to global health.
-
Strategic Task Forces
Una Europa heeft zes transversale thema’s vastgesteld en ingevoerd als leidende beginselen voor samenwerking. Deze thema’s hebben als doel het personeel en de studenten van Una Europa te helpen deze thema's in concrete acties om te zetten.
-
Bioengineering and biophysics of viral hemorrhagic fever
Viral hemorrhagic fever (VHF) is a group of acute diseases caused by highly infectious viruses including Ebola, Lassa, Dengue viruses. Its high mortality rate poses high risk to public health, however, studies on VHF have been hampered due to the non-availability of proper models and incomplete knowledge…
-
Size effects in microstructured superconductors and quantum materials
We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.
-
Activity-based protein profiling of glucosidases, fucosidases and glucuronidases
Promotores: H.S. Overkleeft, G.A. van der Marel, Co-promotor: B.I. Florea
-
Vervolgopleidingen
Met het afronden van je bachelor zet je een belangrijke stap. Maar daarmee is je academische vorming nog niet helemaal ‘af’. Veel opleidingen en banen vragen om meer. Daarom stimuleert de Universiteit Leiden je om na je bacheloropleiding door te gaan met de masteropleiding. Jouw Leidse bachelordiploma…
-
Arbeidsmarkt
Na de master kiezen de meeste alumni voor een baan in het bedrijfsleven of bij de overheid.
-
Don't Blink: Detecting transiting exoplanets with MASCARA
This thesis describes the Multi-site All-Sky CAmeRA (MASCARA), which consists of two small robotic telescope designed to detect exoplanets around the brightest stars in the sky.
-
Nanodeeltjes – redox eiwit biohybriden
Kunstmatige fotosynthese heeft als doel om via chemische processen zonne-energie om te zettn in brandstof. Semi-kunstmatige fotosynthese is een hybride aanpak waarbij chemische maar ook biotechnologische processen worden gebruikt. Wij hebben als doel om een hybride systeem te ontwikkelen met behulp…
-
Footprint family: Concepts, classification, integration, and benchmarking against planetary boundaries
How to bring together different footprints into an integrated family and what are the synergies? What are the roles of inventory analysis and characterization in measuring individual footprints and how these affect a footprint family? How to benchmark environmental footprints against related planetary…
-
Onderzoek
Hoe verwerven mensen taal? Hoe kun je je brein trainen? Wat is het effect van stress op het brein van een ongeboren kind? LIBC-onderzoeksthema's variëren van psychiatrische stoornissen tot cognitieve robotica en van taalverwerking tot de impact van sociale factoren. Maak kennis met verschillende belangrijke…
-
Factors affecting galanthamine production in Narcissus
Factors affecting galanthamine production in Narcissus
-
Representative Bureaucracy in the Age of Artificial Intelligence (AI)
Hoe en in welke mate beïnvloedt AI de vertegenwoordiging van burgers in openbare dienstverlening en interacties tussen staat en burger?
-
against antimicrobial resistant bacterial infections - next stage development of antimicrobial peptides
Promotie
-
Development of Machine Learning-Derived Digital Biomarkers for Trial@Home Clinical Trials
Promotie
-
A bioorthogonal chemistry approach to the study of biomolecules in their ultrastructural cellular context
In this thesis the combinatorial use of bioorthogonal labelling and Electron Microscopy (EM)-based imaging techniques is explored to enable observations of specific molecular targets in their ultrastructural context within the cell.
-
Robert Verpoorte
Wiskunde en Natuurwetenschappen
-
Tomer Fishman
Wiskunde en Natuurwetenschappen
-
Frits Rosendaal
Faculteit Geneeskunde
-
Shiza Aslam
Wiskunde en Natuurwetenschappen
-
Nieuw ontdekte plantensoorten slaan mangaan op in blad
Leidse wetenschappers hebben een nieuw plantengeslacht met twee nieuwe soorten ontdekt bij een potentiële nikkelmijn in Indonesië. Opmerkelijke eigenschap van de planten: ze slaan mangaan op in hun blad.
-
Over Museums, Collections & Society
Museums, Collections & Society is een stimuleringsprogramma van de faculteiten geesteswetenschappen en archeologie wat onderzoek met collecties wil bevorderen, onderwijs op dit gebied wil stimuleren en de ethische vragen wil stellen omtrent de herkomst van deze collecties.
-
Preclinical validation of putative targets in cardiovascular and metabolic disease
Cardiovascular disease is the number one cause of death worldwide. The most important risk factor for developing this disease is high cholesterol levels in the blood.
-
Anti-microbial and Anti-biofilm compounds From Indonesian Medicinal Plants
Promotor: C.A.M.J.J. van den Hondel, Co-promotor: Sandra de Weert
-
Computed fingertip touch for the instrumental control of musical sound with an excursion on the computed retinal afterimage
Promotor: Prof.dr. S. Haring
-
Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
-
Explorations of Water Oxidation Catalysis in Explicit Solvent
In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.
-
Inhibitor discovery of phospholipases and N-acyltransferases
In this thesis an activity-based probe was discovered that could visualize the activity of PLAATs. With an optimized gel-based ABPP assay in hand, screening of a compound library led to the discovery of alpha-ketoamides as a hit for PLAAT3.
-
Dear Future Me
Behavioral and neural mechanisms underlying self-concept development in relation to educational decision-making in adolescence
-
Self adjuvanting immunopeptides: Design and synthesis
Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.
-
Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
-
Linking the gene regulatory network with the functional physical structure of whole-genome engineered Arabidopsis mutants : an HR-MAS NMR-based
Climate change is a challenge for both current and future generations. New biological resources have to be developed in order to meet the demand for energy as well as the demand for food.
-
Impact en stad
De Universiteit Leiden en de stad Den Haag werken nauw samen om de impact van ons onderzoek en onderwijs te vergroten en zo maximaal bij te dragen aan de ontwikkeling van de stad.
-
Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
-
Sustaining Ethical Aquatic Trade (SEAT)
Creating a framework to assess the sustainability of fish farms which will set sustainability standards and give consumers information about the the sustainability and safety of their seafood.
-
Causal Discovery from High-Dimensional Data in the Large-Sample Limit
Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets
-
It's just a phase: High-contrast imaging with patterned liquid-crystal phase plates to facilitate characterization of exoplanets
This thesis aims to demonstrate how the achromatic nature and design flexibility of liquid-crystal optics can be used to improve high-contrast imaging instruments to facilitate detailed exoplanet characterization.
-
Activity-based protein profiling in drug discovery
In the last decades, activity-based protein profiling (ABPP) has emerged as a powerful chemical tool that may aid the ever-challenging drug discovery process.
-
Student projects
To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.
-
Medewerkers
MCS bestaat uit vijf medewerkers, die allen sterke banden hebben met de ‘museums and collections’ opleiding bij de faculteit geesteswetenschappen en ‘heritage and museums’ bij de faculteit archeologie.
-
The structure of a working catalyst: from flat surfaces to nanoparticles
Promotor: Prof.dr. J.W.M. Frenken
-
the basis of CSF PK: impact of mechanisms of blood-to-brain transport and within brain distribution
Promotor: M. Danhof, Co-promotor: E.C.M. de Lange
-
Onderwijs
BSc-programma’s: ‘Political Science’, ‘International Relations and Organisations’. MSc-opleiding: Political Science, met specialisaties ‘International Organisation’; ‘Dutch Politics; ‘Nationalism, Ethnic Conflict, and Development’; ‘International Politics’; ‘Political Legitimacy and Justice’; ‘Democracy…
-
Libya Since the 2011 Revolution: Troubles, Causes, and Future
Professor Dirk Vandewalle is een internationaal veelgevraagde en gerenommeerde Libië-expert. In deze lezing gaat hij in op twee essentiële vragen over de huidige situatie in Libië. Hoe komt het dat het Libische politieke systeem zo fragiel geworden is? En hoeveel hoop is er nog dat Libië als eenheid…
-
Data-Driven Risk Assessment in Infrastructure Networks
Leiden University and the Ministry of Infrastructure and Water Management are involved in a collaboration in the form of a research project titled 'Data-Driven Risk Assessment in Infrastructure Networks'
-
CO2 reduction toward liquid fuels : on heterogeneous electrocatalysts and heterogenized molecular catalysts
With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.
-
Allosteric modulation by sodium ions and amilorides of G protein-coupled receptors
Promotor: A.P. IJzerman