Artificial intelligence algorithms govern in subtle, yet fundamental ways, the way we live and are transforming our societies. The promise of efficient, low‐cost or ‘neutral’ solutions harnessing the potential of big data has led public bodies to adopt algorithmic systems in the provision of public…

In this thesis we present several methods to automate tomographic reconstruction algorithms and several novel tomographic reconstruction algorithms with the focus on being easily applicable and efficient to use.

Promotores: H.W. Lenstra, K. Belabas (University of Bordeaux)

This thesis covers several aspects of quantum algorithms for near-term quantum computers and its applications to quantum chemistry and material science.

Promotor: J.N. Kok, P.E. Slagboom Co-promotor: J.F.J. Laros

Promotor: Robert Tijdeman, Co-promotor: Cornelis Kraaikamp

Structural variants (SVs) are the hidden architecture of the human genome, and are critical for us to understand diseases, evolution, and so on.

Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters

Quantum computing is an emerging technology, which holds the potential to simulate complex quantum systems beyond the reach of classical numerical methods.Despite recent formidable advancements in quantum hardware, constructing a quantum computer capable of performing useful calculations remains challenging.In…

Het onderzoek dat wordt gedaan binnen het Instituut Politieke Wetenschap heeft als gemene deler dat er vanuit verschillende politicologische sub-disciplines wordt gekeken naar de dynamiek van en wisselwerking tussen politieke instituties, individuele besluitvorming en collectief gedrag.

Promotor: R. Tijdeman, Co-promotor: H.J.J. te Riele

Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

This thesis addresses questions on effectively using variational quantum circuits for machine learning tasks.

Modern optimization algorithms offer solutions for architectural decisions like spatial, structural and energy efficiency. A young computer scientist from Leiden University co-authored a paper that won the Best Paper Award at a leading conference in Krakow during the summer.

We present an extensive study of methods for exactly solving stochastic constraint (optimisation) problems (SCPs) in network analysis. These problems are prevalent in science, governance and industry.

Multi-objective evolutionary computation aims to find high quality (Pareto optimal) solutions that represent the trade-off between multiple objectives.

Analytical tools for environmental design and management in a systems perspective. The combined use of analytical tools.

Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.

Multi-criteria optimalisatie is een effectieve techniek voor het vinden van optimale oplossingen die een afweging bieden tussen verschillende, tegenstrijdige criteria. Het heeft zijn toepassing gevonden in de wereld om ons heen omdat bij het oplossen van praktische, re¨ele wereld problemen men gewoonlijk…

Wat is het effect van maatschappelijke veranderingen, persoonlijke levensomstandigheden en migratiebeleid op iemands besluit te migreren?

In this special edition of Information Polity there is a focus on the transparency challenges of using algorithms in government in decision-making procedures at the macro-, meso-, and micro-levels.

In dit artikel onderzoekt Amandine Lerusse hoe de volgorde van prestatie-informatie de prioriteringsbeslissingen van lokale politici beïnvloedt.

In dit artikel wordt het concept van probleemprioritering binnen de context van bestuurskundig onderzoek verkend.

De coronacrisis is de ultieme test voor bestuurders. Hoe houden nationale politieke leiders zich staande in hectische, dynamische tijden? Martin Lodge (London School of Economics and Political Science) en (Arjen Boin (Instituut Politieke Wetenschap Universiteit Leiden) bekijken de ervaringen opgedaan…

Op 20 maart 2019 verdedigde Tim Dekkers zijn proefschrift 'Mobility, Control and Technology in Border Areas: Discretion and Decision-making in the Information Age'. Het promotieonderzoek is begeleid door promotoren prof. dr. J.P. van der Leun en prof. dr. M.A.H. van der Woude.

Promotor: A.P.IJzerman Co-promotor: A. Bender

There is a need for alternative methods to replace, reduce and refine (3R) animal experimentation. Combining experimental data from high-throughput in vitro studies with in silico modeling is a promising approach to unravel the effect of chemicals on living cells and to gain a better understanding of…

Despite being the object of intense study, embryonic development has been difficult to model due to a number of reasons. First, complex tissues can be comprised of many cell types, of which we probably only know a subset.

Team Syntax Error, met Bas Nieuwenhuizen, Mathijs van de Nes, Niels ten Dijke, alle drie masterstudenten Computer Science, heeft de Benelux Algorithm Programming Contest gewonnen en heeft zich daarmee geplaatst voor de Northwestern European Regional Contest in Zweden, op 29 en 30 november.

Op 27 september promoveert Josephine Hartmann op haar proefschrift: A blessing in disguise?! Discretion in the context of EU decision-making, national transposition and legitimacy regarding EU directives.

The main topic of this PhD thesis is the Arakelov ray class group of a number field, an algebraic object that contains both the ideal class group structure and the unit group structure.

De huidige en toekomstige quantumcomputers vormen dezelfde uitdaging als de laser in zijn begindagen. In theorie werd voorspeld dat de laser een bron van zeer speciaal, zeer krachtig licht zou zijn. Maar in die tijd waren er geen duidelijke toepassingen voor. Critici van het idee noemden het een probleem…

Promotores: J.N. Kok, H.J. Hoogeboom

Het Leidse team 'Geen Syntax', bestaande uit Bas Nieuwenhuizen, Mathijs van de Nes en Raymond van Bommel, heeft in Utrecht de Benelux Algorithm Programming Contest (BAPC) 2013 gewonnen. Deze Leidse studenten wiskunde en informatica losten de 10 opgaven een uur sneller op dan alle andere teams.

This thesis involves three topics: benchmarking discrete optimization algorithms, empirical analyses of evolutionary computation, and automatic algorithm configuration.

Promotor: H.W. Lenstra

HEPGAME is a research project that combines the world’s fastest computer algebra system for High Energy Physics equations, FORM, with insights from artificial intelligence. The name combines High Energy Physics and Games.

This thesis is a collection of theoretical works aiming at adjusting quantum algorithms to the hardware of quantum computers.

Promotor: J. N. Kok, Co-promotor: A. J. Knobbe

An algorithm is discussed to compute the exponential representation of principal units in a finite extension field F of the p-adic rationals.

Promotors: Prof.dr. T.H.W. Bäck, Prof.dr. B. Sendhoff (Technische Universität Darmstadt)

Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich

In this dissertation several settings in the Online Learning framework are studied. The first chapter serves as an introduction to the relevant settings in Online Learning and in the subsequent chapters new results and insights are given for both full-information and bandit information settings.

Promotor: J.M. van den Broek Co-promotor: M.C. de Vries

To an algebraic curve C over the complex numbers one can associate a non-negative integer g, the genus, as a measure of its complexity.

Yvonne Erkens en Fieke Weber, beiden werkzaam bij de Afdeling Sociaal Recht hebben onlangs namens het journal ILaRC een panel georganiseerd tijdens het ISLSSL World Congres in Rome. Dit panel, getiteld ‘Landmark Decisions on Fundamental Labour Standards: A Decade of Impact’, werd georganiseerd ter ere…

The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.

In this thesis we will explore the use of fuzzy systems theory for applications in bioinformatics.