1,409 zoekresultaten voor “leiden university centre for linguistics” in de Publieke website
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Applications of paramagnetic NMR spectroscopy for protein research
The aim of the research presented in this thesis was to develop new methods forchallenging systems in liquid-state NMR using paramagnetic effects generated by thetwo-armed probe CLaNP-5.
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Reconstruction Methods for Combined HAADF-STEM and EDS Tomography
The research in this thesis is focused on tomographic reconstruction based on two imaging modalities in electron microscopy.
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Advanced in vitro models for studying drug induced toxicity
Promotor: B.van de Water, Co-promotor: L.S.Price
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Advances in computational methods for Quantum Field Theory calculations
In this work we describe three methods to improve the performance of Quantum Field Theory calculations.
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Imaging of alkyne-functionalized ruthenium complexes for photoactivated chemotherapy
In photoactivated chemotherapy (PACT), a biologically active compound is caged by a light-cleavable protecting group.
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The astrochemical factory: A solid base for interstellar reactions
In this thesis chemical and physical processes in the ice mantles on interstellar dust grains are studied.
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Liposomes as delivery system for allergen-specific immunotherapy
In this book liposomes are explored as delivery system for allergen-specific immunotherapy. Both cationic and anionic formulations are prepared with Bet v 1, one of the allergens in birch pollen.
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Lattice models for Josephson junctions and graphene superlattices
In this thesis we study quantum transport phenomena on the nanometer scale, in two classes of materials: topological insulators with induced superconductivity and graphene superlattices.
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“Leiden linguists play a key role in linguistics”
Van 2 tot 5 september 2015 is Leiden het toneel van een van de grootste linguïstische congressen ter wereld: de Societas Linguistica Europaea (SLE) Annual Meeting 2015. Hoe heeft Leiden zo'n prominente positie binnen de Taalkunde gekregen? Een gesprek met taalwetenschapper Arie Verhagen.
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Single cell mechanics for disease biology and pharmacology
In this thesis, we describe the potential of cell mechanical phenotyping for immune cell characterization, diagnosis, drug testing, as well as treatment of disease.
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Eerste informatieavond University College
Het Leiden University College The Hague gaat in september 2010 van start. In de aanloop naar de opening houdt het LUCTH een open dag op maandag 7 december. Dean Chris Goto-Jones stelt het College aan u voor.
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Peer education as an opportunity for practicing respect for sexual and gender diversity
Het centrale doel van dit proefschrift is inzicht verschaffen in hoe de implementatie van een peer educator-interventie van invloed kan zijn op de houding van leerlingen tegenover LHBT-leeftijdgenoten en op de relatie tussen deze houdingen en reflectie over burgerschap.
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Patrick Gouw
Universitaire Bibliotheken Leiden
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Anita Keizers
Universitaire Bibliotheken Leiden
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Piqani en Jesse houden lezing aan het Centre for Constitutionalism and Human Rights in Praag
Darinka Piqani en Moritz Jesse, beiden verbonden aan het Europa Instituut Leiden, waren uitgenodigd als sprekers bij het Centre for Constitutionalism and Human Rights dat deel uitmaakt van de Rechtenfaculteit van de Charles Universiteit in Praag.
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Veel aandacht voor nieuwe database corruptieschandalen van Centre for Public Values & Ethics
Op 16 juni 2015 lanceerde Bestuurskundigen Toon Kerkhoff en Patrick Overeem hun database ’Corruption & Integrity in the Netherlands (1945 - present)'.
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Peptide-based probes for protein N-Methyltransferases
The work described in this thesis focuses on the development of linear or cyclized peptide probes against protein N-methyltransferases to characterize their specific binding behavior, providing further binding details for inhibitory activity study.
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Imagining Justice for Syria: Water Always Finds Its Way
Op 29 april 2020 verdedigde Beth Van Schaack haar proefschrift 'Imagining Justice for Syria: Water Always Finds Its Way'. Het promotieonderzoek is begeleid door promotor prof.dr. C. Stahn.
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Exploring the mechanisms of metastatic onset for novel treatment strategies
This thesis represents a comprehensive investigation into the control of cancer stemness and metastatic initiation using a combination of advanced zebrafish xenograft models and in vitro assays.
- From basic research to therapy development for neuromuscular disorders
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Quantitative pharmacological modelling for optimizing treatment of sepsis
Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…
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Statistical modelling of time-varying covariates for survival data
This dissertation focuses on developing new mathematical and statistical methods to properly represent time-varying covariates and model them within the context of time-to-event analysis.
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Algorithms for analyzing and mining real-world graphs
Promotor: Prof.dr. J.N. Kok, Co-Promotor: W.A. Kosters
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Predicting the future: Predictive control for astronomical adaptive optics
The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.
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Supramolecular polymer materials for biomedical applications and diagnostics
Self-assembly is an abundant process in nature and is vital to many processes in living organisms.
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Novel Immune Cell-Based Therapies for Atherosclerosis
Promotor: Prof.dr. J. Kuiper
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Methods and Tools for Mining Multivariate Time Series
Mining time series is a machine learning subfield that focuses on a particular data structure, where variables are measured over (short or long) periods of time.
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New polymyxin antibiotics for old problems: addressing nephrotoxicity and resistance
Polymyxins are clinically used antibiotics, discovered in mid-20th century. Once abandoned due to excessive nephrotoxicity, they are now used increasingly to address infections caused by multi-drug resistant Gram-negative bacteria.In this thesis, we describe the development and synthesis of analogues…
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The hunt for frozen organic molecules in space
Complex Organic Molecules (COMs) have been detected in objects across different stages of stellar evolution.
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Intermittency and Number Expansions for Random Interval Maps
This dissertation consists of two parts, each of which considers a different research area related to random interval maps. In the first part we are interested in random interval maps that are critically intermittent.
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Inverse problems for universal deformation rings of group representations
Promotor: Prof.dr. P. Stevenhagen
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Development of life cycle assessment for residue-based bioenergy
Wat zijn de belangrijkste thema's in het uitvoeren van systemen voor bio-energie ?
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Universiteit Leiden en LUMC treden toe tot Netherlands Centre for One Health
Het Netherlands Centre for One Health (NCOH) is uitgebreid met de Universiteit Leiden en het LUMC. De komst van de Leidse instellingen versterkt het academische netwerk waarin onder andere het probleem van antimicrobiële resistentie wordt onderzocht.
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Statistical learning for complex data to enable precision medicine strategies
Explaining treatment response variability between and within patients can support treatment and dosing optimization, to improve treatment of individual patients.
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Network analysis methods for smart inspection in the transport domain
Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.
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Mechanism-based inhibitors and probes for neuraminidases
Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
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2012 Onderzoekers Geesteswetenschappen ontvangen Veni-subsidies
De veelbelovende, pas gepromoveerde onderzoekers kunnen de komende drie jaar hun wetenschappelijke ideeën verder uitwerken dankzij een Veni van NWO. Een Veni-financiering bedraagt maximaal 250.000 euro en is één van de persoonsgebonden financieringsvormen van NWO om wetenschappelijk talent te stimul…
- Elastin-like polypeptide micelles for vaccine delivery
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Dit zijn de zeven Veni-laureaten van Geesteswetenschappen
Aan maar liefst zeven wetenschappers van de Faculteit Geesteswetenschappen is een Veni-financiering toegekend. Veni’s zijn gericht op excellente onderzoekers die onlangs gepromoveerd zijn. Met de beurs van maximaal 250.000 euro kunnen de laureaten gedurende drie jaar hun eigen onderzoeksideeën verder…
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Succesvolle PhD Workshop Hazelhoff Centre for Financial Law: Beyond Bank Resolution: Resolution and its Frontiers
Op donderdag 7 en vrijdag 8 december 2017 organiseerden het Hazelhoff Centre for Financial Law van de Leidse rechtenfaculteit en het European University Institute in Florence een PhD workshop in Leiden.
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Beijing Normal University bezoekt Leiden for Astronomie Summer School
Op 8 juli verwelkomde de Leidse Sterrewacht acht bachelor studenten van de Beijing Normal University voor de BNU Astronomie Summer School. In twee weken tijd volgenden de Summer School-studenten een interactief programma over computationele astrofysica. ‘Het verbaast me hoeveel je kunt leren in twee…
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Pesticides and health – challenges and opportunities for exposure assessment
The aim is to develop methods to assess environmental and occupational exposure to (individual) pesticides, to be applied in epidemiological studies investigating pesticide exposure and human health. Furthermore, we aim to investigate the potential association between exposure to pesticides and Parkinson’s…
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Terrestrial field trials for side-effects of pesticides
The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink
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Chemistry in embedded disks: setting the stage for planet formation
To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.
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Development of life cycle assessment for residue-based bioenergy
Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs
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Biomimetic Copper Catalysts for the Electrochemical Oxygen Reduction Reaction
Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.