Corruption, integrity (or a lack thereof…) and public values are near omnipresent elements in public administration and politics of all times. Cases of corrupt public officials and politicians continuously emerge. Strangely enough, however, it often remains unknown what actually occurred, how something…

De masteropleiding Politics, Culture and National Identities, 1789 to the Present van de Universiteit Leiden geeft je de mogelijkheid om op een nieuwe manier Europese politiek en identiteit te onderzoeken.

This thesis describes the development of a variety of mannosylated conjugates. Antigen presenting cells bear mannoside recognizing receptors that actively transport antigen into the cell. This thesis exploits this feature for the development of improved vaccines.

De specialisatie Politics, Culture and National Identities, 1789 to the Present (research) van de Universiteit Leiden brengt je in de voorhoede van de nieuwe benadering van de manier waarop in Europa politiek en identiteit worden opgevat.

The course "Presenting Medieval Research at International Conferences" is open for registration. The deadline for registration is 10 September 2020.

In dit artikel doen Bart Schuurman en Sarah Louise Carthy onderzoek naar de oorzaken van terrorisme door verschillen en overeenkomsten tussen links-, rechts- en jihadistische extremisten te vergelijken.

In the thesis the dynamics of strategies is studied from two perspectives.In the first part of the thesis strategies are considered to be opinions present in a community.

Within the field of astronomy, understanding how galaxies grow and evolve from the Big Bang to the present day is a challenging and complex question.

In this thesis, we present new laboratory data of interstellar dust analogues.

This thesis presents insights from our study of various correlated electron systems with a scanning tunneling microscope (STM). In ordinary metals, electron-electron interactions exist, but get substantially screened due to the sheer number of electrons.

Promotor: Prof.dr. T. Hankemeier, Co-promotor: Theo Reijmers

Promotores: Prof.dr. M. Franx, Prof.dr. M. Kriek (Univ. of California at Berkeley)

Nanoparticles can be used as delivery systems for both small molecules and macromolecules such as proteins, peptides or oligonucleotides. This thesis focuses on the use of liposomes, nanometric vesicles formed by a lipid bilayer enclosing an aqueous core. Liposomes are highly versatile delivery syst…

Promotor: Ronald Cramer, Co-promotor: Serge Fehr

Business Process Model and Notation (BPMN) has become the standard for business processes diagrams.

In this thesis, we extend the concept of null models as canonical ensembles of multi-graphs with given constraints and present new metrics able to characterize real-world layered systems based on their correlation patterns.

The next generation of high-contrast imaging instruments on space-based observatories requires sophisticated wavefront sensing and control in addition to a high-performance coronagraph.

Co-ordination Action for Innovation in Life-Cycle Analysis for Sustainability: deepening, broadening and leaping forward the LCA methodology.

Promotor: W. Jaffe, Co-promotor: K. Meisenheimer

Promotor: Prof.dr. A. Achucarro

Promotor: K.H. Kuijken

The unit residue group, to which the present thesis is devoted, is defined using the norm-residue symbol, which Hilbert introduced into algebraic number theory in 1897.

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

At the largest scales, two ingredients dictate the distribution of matter in the Universe. The first is dark matter, acting as an invisible scaffolding held together by gravitational forces.

Heterogeneous catalysis is one of the fundamental processes of modern life, being common in industrial refinery and hydrogen vehicles, all the way to the living cell. The dissociation of H2 on Cu(111) is an important benchmark system for studying heterogeneous catalysis, with a large and varied amount…

Streptomyces present a valuable platform for natural product discovery. Lugdunomycin is a novel angucycline-derived polyketide from Streptomyces sp QL37, with unprecedented skeleton and antimicrobial activity.

Promotores: Prof.dr. H. van Veen & Prof.dr. W. de Boer (Wageningen University)

Promotores: Prof.dr. C.U. Keller, Prof.dr. H.C. Gerritsen

In this thesis we present several methods to automate tomographic reconstruction algorithms and several novel tomographic reconstruction algorithms with the focus on being easily applicable and efficient to use.

De onderzoeksmaster History (research) van de Universiteit Leiden biedt een keuze uit vijf specialisaties waarin je je richt op historische processen, geschiedkundig onderzoek, historiografie en methodologie.

In this course, we will focus on the fascinating history of the Arabic Medieval World. We will take you on a journey through the Middle Ages. All along, we will present you with historiographical debates and dilemmas and travel back and forth in time explaining to you how events of the past affected…

Promotor: M. Franx, Co-Promotor: I.F. Labbé

This thesis explores the theoretical and observational properties of distant massive galaxies that harbour active black holes in their centres and shine brightly at radio wavelengths.

Supervisor: S.F. Portegies Zwart Co-Supervisor: A.G.A. Brown

Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.

Promotor: Prof.dr. L.J. Slikkerveer

Promotores: J. Kok, M. Chaudron (Chalmers University)

Particles are omnipresent in biopharmaceutical products. In protein-based therapeutics such particles are generally associated with impurities, either derived from the drug product itself (e.g. protein aggregates), or from extrinsic contaminations (e.g. cellulose fibers).

The aim of this project was to estimate emissions from lead products-in-use for the past, the present and the future and assess the development of toxicological risks associated with these products.

Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.

The high velocity tail of the total velocity distribution of stars provides essential insight into fundamental properties of the Galaxy.

The present thesis focuses on the pharmacological concept of drug-target interaction, which dates back to the beginning of modern pharmacology.

This thesis focusses on the temperature structure in protoplanetary disks. The relation between structures seen in the dust and gas-phase molecules is investigated.

Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.