Integrating life cycle assessment (LCA) with life cycle costing (LCC) offers the opportunity to simultaneously analyze the environmental and economic aspects of product alternatives, for the integration of which a unified computational has been proposed by Heijungs et al. (2013) [1]. The project aims…

How do you make a technology sustainable that does not even exist yet? Well, by bringing together an interdisciplinary team of pioneering European experts right at the start and paying attention to sustainability right from the development phase.

Description of Atlas of the surfacewater concentrations of pesticides in the Netherlands, a pilotstudy.

Where and how are critical materials currently used and how can this information be used to develop scenarios about their future demand.

The Economics and Governance specialisation of the Master in Public Administration teaches you to formulate problem-solving approaches to concrete policy issues found at the intersection between economics and public administration. This specialisation is a unique joint offering of the Department of…

Do selenium nanoparticles in fish food cause subtle alterations in behavior of fish: effect of particles size and concentration?

What are the environmental trade-offs for SMEs considering moving from monoculture aquaculture practice towards IMTA? What are the environmental trade-offs comparing IMTA species with their conventional monoculture alternatives?

Aan de hand van drie onderzoekslijnen wordt de verbinding tussen zorg en bestuur gemaakt. Binnen deze drie onderzoekslijnen wordt een multi-level benadering gehanteerd. Dat betekent dat we ons richten op vraagstukken op het niveau van het gezondheidszorgstelsel, het niveau van organisaties en netwerken…

Leiden Institute of Advanced Computer Science (LIACS)

Promotor: A. Kros, Co-promotor: R.R.C.L. Olsthoorn

Drug-induced liver injury (DILI) is one of the main reasons for drug attrition during pre-clinical and clinical phases of drug development as well as for drug withdrawal post-marketing.

Promotor: J.A. van Veen, Co-promotor: E.E. Kuramae

Promotor: Prof.dr. A. Doelman, Co-promotor: V. Rottschäfer

Sepsis is a life-threatening condition caused by a dysregulated host response to infection, it is associated with significant morbidity, mortality, and with a high financial burden on global healthcare systems. Bacterial infections are the primary cause of sepsis, but the growing prevalence of antimicrobial…

Supervisor: P.J.J. Hooykaas

Promotor: E. F. van Dishoeck, Co-promotor: C. Walsh

In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).

A century ago, it was unclear whether the stars in the sky were clustered in groups, or widely spread in the universe.

Invasive lobular carcinoma (ILC) is the second most common type of breast cancer.

Promotor: Prof.dr. T. Hankemeier

Planets are formed in disks of gas and dust around young stars.

Promotor: A.P. IJzerman Co-promotor: L.H. Heitman

A remarkable population of short period transiting rocky exoplanets with equilibrium temperatures on the order of 2,000 K has recently been discovered.

Promotoren: Prof.dr. G.R. de Snoo en Dr. R. Heijungs

Quantum hardware comes with a different computing paradigm and new ways to tackle applications. Much effort has to be put into understanding how to leverage this technology to give real-world advantages in areas of interest for industries such as combinatorial optimization or machine learning.

This thesis is about the study of hydrocarbons via infrared spectroscopy.

Promotor: Prof.dr. G.P. van Wezel

Understanding how galaxies form, interact, and evolve comes largely from comparing theory predictions with observational data. Numerical simulations of galaxies provide the most accurate approach to testing the theory, as they follow the non-linear evolution of gas and dark matter in great detail and…

Light-Harvesting Complex II (LHCII) is responsible for light absorption and excitation energy transfer in plants and photosynthetic algae, while in high light it undergoes conformational changes by which it quenches excitations to prevent photodamage.

Fungal infections pose a significant threat to individuals with compromised immune systems and despite advancements in diagnosis and treatment, they continue to jeopardize patient’s health.

Promotores: Prof.dr. F.S. de Boer, Prof.dr. J.J.M.M. Rutten (Radboud Universiteit Nijmegen)

Heart failure is a major health care problem with high mortality.

Promotor: Prof.dr. J.N. Kok

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Dissolving microneedles are a subgroup of microneedle types that completely dissolve within the skin. During this dissolving process the vaccine, stored in the needle matrix, is released into the skin.

The redox-conversion reaction of metal-disulfide and metal-thiolate complexes are important, as they may shed light on electron-transfer reactions that often occur in Nature.

Promotor: M.A.G.J. Orrit

Op 13 januari 2022 verdedigde Pie Habimana het proefschrift 'Harmful Tax Competition in the East African Community'. Het promotieonderzoek is begeleid door prof.dr. H. Vording en prof.dr. S.C.W. Douma (UvA).

In the CarbonCap project, consumption oriented technological options and policy measures are identified as an addition to the present EU and world climate policy.

This thesis is a collection of experimental attempts to enhance photoluminescence of fluorescent molecules and quantum dots with single gold nanorods (GNRs) and relevant applications.

Promotor: C. W. J. Beenakker, Yu. V. Nazarov, Co-promotor: J. Tworzydlo

Het onderzoek van eLaw sluit vooral (maar niet uitsluitend) aan bij het facultaire onderzoeksprogramma Effective Protection of Fundamental Rights in a Pluralist World. De centrale onderzoeksvraag van dit programma is: welke kansen en bedreigingen vloeien voort uit de institutionele en normatieve diversiteit…

Single-molecule spectroscopy has become a powerful method for using organic fluorescent molecules in numerous applications.

Promotor: Prof.dr. C.W.J. Beenakker

Membrane fusion is a vital process in living organisms and is mediated by zipper-like proteins.

The objective of this study was to investigate the expression and function of GRHL2 in different breast cancer subtypes.

Promotor: Prof.dr. H.J.M de Groot, Co-Promotor: A. Alia

Biological cells, the basic building blocks of all life forms, are surrounded by a lipid membrane. More than half of the membrane is occupied by membrane proteins, which can regulate the cell functionality through specific arrangements.

Balsaminaceae is a diverse plant family characterized by a huge floral morphological diversity.

Vancomycin is a last-resort antibiotic for the treatment of many Gram-positive bacterial infections, while remaining inactive against Gram-negative strains.