1,508 zoekresultaten voor “koen from” in de Publieke website
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The developing infant gut microbiota: mathematical predictions of the effects of oligosaccharides
A complex community of microbes develops in the infant gut shortly after birth. We call this community the infant gut microbiota. The microbiota influences the health of the infant, which makes the composition and function of the infant gut microbiota an important topic to study.
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Triblock polypept(o)ides for siRNA delivery: unique polymeric designs for versatile carrier systems
Utilizing the polymeric platform of polypept(o)ides, this thesis describes synthesis and investigation of novel triblock copolymers to obtain carrier systems with multiple compartments for efficient siRNA delivery. Although the individual microstructure of nanoparticles differs depending on the polymeric…
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Combining classic and novel tools in the study of Historical Collections of Chinese Materia Medica in the Netherlands
Chinese materia medica (CMM), comprising a diverse array of natural substances from plants, animals, and minerals, has been integral to Traditional Chinese Medicine (TCM) throughout history. This study investigates the dynamic evolution of CMM, noting shifts in species for improved therapeutic effects…
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Probing molecular layers with low-energy electrons
Molecular materials have been a subject of interest in fundamental research and applications for decades, and have been studied as bulk crystals, (thin) films and as individual molecules, due to the large variety in their properties. This dissertation explores pentacene crystals near the two-dimensional…
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Strafrecht & Criminologie
Het Instituut voor Strafrecht & Criminologie houdt zich bezig met onderzoek en onderwijs op respectievelijk het gebied van het straf(proces)recht en de criminologie.
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Size effects in microstructured superconductors and quantum materials
We find ourselves in an era of transition, not just towards a more computing- and data-driven society but also away from unsustainable fossil fuels as an energy source.
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Manipulating carbon nanotubes Towards the application as novel field emission sources
Promotores: T.H. Oosterkamp, N. de Jonge
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Chitin in the fungal cell wall: towards valorization of spent biomass of Aspergillus niger
Aspergillus niger is an important industrial producer of organic acids and enzymes producing large amounts of spent fungal biomass.
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Radicals in arithmetic
Promotor: Prof.dr. P. Stevenhagen, Co-promotor: B. de Smit
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Histone-DNA assemblies in archaea. Shaping the genome on the edge of life
All life on earth contains DNA, which is used to store biological information. Organisms compact their DNA in order for it to fit inside their cell(s).
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Applications of graphene in nanotechnology : 1D diffusion, current drag and nanoelectrodes
Graphene nanoribbons (GNRs) are used as a current carrying substrate in investigation of current-induced forces in a low-temperature STM (chapter 2).
- Medieval Latin (5 ECTS)
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Click-to-release for immune cell activation
This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…
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Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
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Fundamental research on the voltammetry of polycrystalline gold
Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.
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Low-temperature spectroscopic studies of single molecules in 3-D and on 2-D hosts
Spectroscopic studies on fluorescent single molecules in organic condensed matter does not only provide information about the molecule itself, but also its near environment. By suppression of phonon-induced broadening of spectral lines through cooling to low temperatures, small changes in the spectral…
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Trading Responsibility: navigating national burdens in a globalized world
International trade has played a major role in defining the modern global economy. Trade, however, entangles the environmental pressures of economic sectors, giving the illusion of environmental improvements, while the opposite may be occurring.
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Pushing the characterization of exoplanet atmospheres down to temperate rocky planets in the era of JWST
One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.
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Risk bounds for deep learning
In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.
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Nieuwe publicatie Bas de Melker
Op 14 oktober 2021 verschijnt "Metamorfose van Stad en Devotie". Het gaat om een handeleditie van de dissertatie van wijlen Bas de Melker over het Amsterdam van de jaren 1385-1435. De dissertatie zelf wordt uitgegeven naar de tekst van Bas de Melker uit 2002, maar er is een epiloog aangehangen over…
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Moet er een verplicht mini-sociaal stelsel komen voor alle werkenden?
BNR, maandag 20 maart 2017, 12:32 en (herhaling) dinsdag 21 maart 2017, 20:10
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34th World Cultural Council Special Recognition Award voor Marike Knoef
8 november jl. heeft Marike Knoef een award gewonnen op de 34ste Award Ceremony van de World Cultural Council (WCC).
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From code to clinic: Theory and practice for artificial intelligence prediction algorithms
Promotie
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‘KLM nam de opdracht net zo serieus als wijzelf’
Hoe kan KLM de meest duurzame luchtvaartmaatschappij blijven? Masterstudenten van het Leiden Leadership Programme duiken de praktijk in en adviseren bedrijven bij grote vraagstukken.
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1200 Noord-Koreaanse posters in één database
Koreaspecialist Koen De Ceuster heeft zo’n 1200 posters uit Noord-Korea samengebracht in een database. De posters zijn volgens De Ceuster van onschatbare waarde voor wetenschappers die het gesloten land beter willen bestuderen. De database wordt op 15 juni gepresenteerd in Leiden.
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Astronaut André Kuipers landt op de universiteit
André Kuipers neemt in zijn gastcollege op 22 januari scholieren en studenten mee op zijn ruimtereis. Zijn missie: leerlingen en studenten warm maken voor wetenschap en techniek.
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essential in characterizing noun classes: Corpus and experimental evidence from Bantu
Lezing, This Time for Africa!
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From reconstructing to constructing languages: How I created two conlangs for a movie about the Neolithic Revolution
Lezing, Comparative Indo-European Linguistics (CIEL) Seminars
- Security and conflict resolution in northern Nigeria: from Boko Haram to farmer-herder violence - The Hague
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Selective fetal growth restriction in identical twins: from womb to adolescence
Promotie
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The input pathways to the circadian clock: from nocturnality to diurnality
Promotie
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Outcome after anterior cervical discectomy: From inferential statistics to Machine Learning
Promotie
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What Works in Suicide Prevention? Lessons from the 113 Helpline
Lezing
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Postdoc on Law, Robots & Society (0.8-1.0 FTE)
Rechtsgeleerdheid, Instituut voor Metajuridica, eLaw - Centrum voor Recht en Digitale Technologie
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Basic Program 2024-2025
The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).
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1.5 miljoen voor ontwikkelen van een nieuwe hemelkaart en spectograaf op een chip
Het gebiedsbestuur Exacte Wetenschappen van NWO heeft twee subsidies toegekend aan Sterrewacht Leiden. Voor het maken van een nieuwe hemelkaart werd één subsidie toegekend aan Koen Kuijken, en voor het ontwikkelen van een nieuw type spectrograaf, gebaseerd op nanotechnologie, werd een subsidie toegekend…
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Brieven als buit
Alledaagse taal uit het verleden kennen wij nauwelijks, maar taalkundig onderzoek van een unieke brievencollectie opent perspectieven. Buitgemaakte brieven van mannen, vrouwen en zelfs kinderen stonden centraal in het Leidse Brieven als Buit-project onder leiding van prof. dr. Marijke van der Wal, dat…
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Fiscaal beleid leidt tot grote verschillen in lastendruk
Op 13 december 2019 wordt de bundel 'Ontwerp voor een beter belastingstelsel' gepresenteerd, waarin economen uit binnen- en buitenland het Nederlands belastingstelsel tegen het licht houden en verbetervoorstellen doen. Koen Caminada en Kees Goudswaard schreven hierin een bijdrage.
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Groot deel zzp'ers betaalt geen inkomstenbelasting
Dankzij een groot scala aan aftrekposten werden de eerste 24.000 euro van de verdiensten van zzp’ers vrijgesteld van inkomstenbelasting. Volgens Koen Caminada, hoogleraar empirische analyse van sociale en fiscale regelgeving, zijn de ‘hogere kosten van zzp’ers een argument voor het betalen van minder…
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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The Infrared Spectrum of Massive Protostars
We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.
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Gauss's theorem on sums of 3 squares, sheaves, and Gauss composition
Promotor: Bas Edixhoven, Promotor: Qing Liu
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Photosynthetic light reactions at the gold interface
Promotor: T.J. Aartsma, Co-promotor: R.N. Frese
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Class invariants for tame Galois algebras
Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit
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Adding fuel to the conflict : how gas reserves complicate the Cyprus question
In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Painting with starlight : optical techniques for the high-contrast imaging of exoplanets
This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.
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SCS Courses
The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.
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Empirical signatures of universality, hierarchy and clustering in culture
In this thesis,