1,480 zoekresultaten voor “koen from” in de Publieke website
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Click-to-release for immune cell activation
This work describes the use of click-to-release chemistry to get spatiotemporal control over immunocytokine activity. Until now, immunocytokines (cytokines coupled to a tumor-targeting-moiety) remained active throughout the body, being able to bind their respective receptors, causing mild to severe…
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Fundamental research on the voltammetry of polycrystalline gold
Voltammetry plays a crucial role in modern scientific research by offering valuable insights into the electrochemical properties of materials, with wide-ranging applications in fields such as materials science, energy storage, corrosion studies, and sensor development.
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Chemical reactivity of O2, CO and CO2 on Cu surfaces
Despite the history of studies on methanol formation from CO2, the dominant elementary reaction steps that constitute the chemical mechanism for this catalyzed process are not determined.
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Pushing the characterization of exoplanet atmospheres down to temperate rocky planets in the era of JWST
One of the key discoveries in exoplanet research over the past decade is the abundance of small planets in our Milky Way. Despite their high numbers, our understanding of their atmospheres remains limited, and it is unknown if they possess atmospheres at all.
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Risk bounds for deep learning
In this thesis, deep learning is studied from a statistical perspective. Convergence rates for the worst case risk bounds of neural network estimators are obtained in the classification, density estimation and linear regression model.
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Overige masters
Bij eLaw verzorgen we een aantal vakken voor de master Jeugdrecht en voor de master International Children's Rights (Advanced LL.M.)
- Medieval Latin (5 ECTS)
- Agenda
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Nieuwe publicatie Bas de Melker
Op 14 oktober 2021 verschijnt "Metamorfose van Stad en Devotie". Het gaat om een handeleditie van de dissertatie van wijlen Bas de Melker over het Amsterdam van de jaren 1385-1435. De dissertatie zelf wordt uitgegeven naar de tekst van Bas de Melker uit 2002, maar er is een epiloog aangehangen over…
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Moet er een verplicht mini-sociaal stelsel komen voor alle werkenden?
BNR, maandag 20 maart 2017, 12:32 en (herhaling) dinsdag 21 maart 2017, 20:10
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34th World Cultural Council Special Recognition Award voor Marike Knoef
8 november jl. heeft Marike Knoef een award gewonnen op de 34ste Award Ceremony van de World Cultural Council (WCC).
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From code to clinic: Theory and practice for artificial intelligence prediction algorithms
Promotie
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‘KLM nam de opdracht net zo serieus als wijzelf’
Hoe kan KLM de meest duurzame luchtvaartmaatschappij blijven? Masterstudenten van het Leiden Leadership Programme duiken de praktijk in en adviseren bedrijven bij grote vraagstukken.
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1200 Noord-Koreaanse posters in één database
Koreaspecialist Koen De Ceuster heeft zo’n 1200 posters uit Noord-Korea samengebracht in een database. De posters zijn volgens De Ceuster van onschatbare waarde voor wetenschappers die het gesloten land beter willen bestuderen. De database wordt op 15 juni gepresenteerd in Leiden.
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Astronaut André Kuipers landt op de universiteit
André Kuipers neemt in zijn gastcollege op 22 januari scholieren en studenten mee op zijn ruimtereis. Zijn missie: leerlingen en studenten warm maken voor wetenschap en techniek.
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essential in characterizing noun classes: Corpus and experimental evidence from Bantu
Lezing, This Time for Africa!
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From reconstructing to constructing languages: How I created two conlangs for a movie about the Neolithic Revolution
Lezing, Comparative Indo-European Linguistics (CIEL) Seminars
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Selective fetal growth restriction in identical twins: from womb to adolescence
Promotie
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The input pathways to the circadian clock: from nocturnality to diurnality
Promotie
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Outcome after anterior cervical discectomy: From inferential statistics to Machine Learning
Promotie
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Basic Program 2024-2025
The basic program comprises a total of twelve courses organized by the Research School, that have been purpose-developed for training and support of PhD students and Research MA students who specialize in Medieval Studies (history, art history, and literary history, in particular).
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What Works in Suicide Prevention? Lessons from the 113 Helpline
Lezing
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1.5 miljoen voor ontwikkelen van een nieuwe hemelkaart en spectograaf op een chip
Het gebiedsbestuur Exacte Wetenschappen van NWO heeft twee subsidies toegekend aan Sterrewacht Leiden. Voor het maken van een nieuwe hemelkaart werd één subsidie toegekend aan Koen Kuijken, en voor het ontwikkelen van een nieuw type spectrograaf, gebaseerd op nanotechnologie, werd een subsidie toegekend…
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Brieven als buit
Alledaagse taal uit het verleden kennen wij nauwelijks, maar taalkundig onderzoek van een unieke brievencollectie opent perspectieven. Buitgemaakte brieven van mannen, vrouwen en zelfs kinderen stonden centraal in het Leidse Brieven als Buit-project onder leiding van prof. dr. Marijke van der Wal, dat…
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The Function of Toll-like receptor 2 in Infection and Inflammation
The function of TLRs in innate immunity has aroused worldwide attention soon after its discovery. Because of the broad functions of TLR2 in innate immunity, the drive for the development of TLR2-targeted vaccines or therapeutic treatments has accelerated in the last decades.
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Probing new physics in the laboratory and in space
The Standard Model (SM) of particle physics fails to explain several observed phenomena and is incomplete. In order to resolve this problem, one may extend the SM by adding new particles.
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The Infrared Spectrum of Massive Protostars
We have conducted a full spectral line survey of the 3-13 micron region of two massive protostars, AFGL 2591 and AFGL 2136, for the first time at high spectral resolution.
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Gauss's theorem on sums of 3 squares, sheaves, and Gauss composition
Promotor: Bas Edixhoven, Promotor: Qing Liu
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Photosynthetic light reactions at the gold interface
Promotor: T.J. Aartsma, Co-promotor: R.N. Frese
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Class invariants for tame Galois algebras
Promotores: B. Erez, P. Stevenhagen, Co-Promotor: B. de Smit
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Adding fuel to the conflict : how gas reserves complicate the Cyprus question
In this research I assess the impact of the recently discovered gas reserves south off Cyprus on the escalation of the Cyprus conflict.
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Lipid model membrane systems as a tool for unraveling the underlying factors for skin barrier dysfunction
Barrier function is the natural role of the skin. The lipid matrix present in the outermost layer of the skin, the stratum corneum is important for this function.
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Painting with starlight : optical techniques for the high-contrast imaging of exoplanets
This thesis describes the development and validation of new high-contrast imaging techniques, with the ultimate goal of enabling the next generation of instruments for ELT-class telescopes to directly image Earth-like extra-solar planets orbiting around nearby stars.
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SCS Courses
The coursework within the Science Communication and Society (SCS) specialisation prepares students for internships and a career in communication about science and health.
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Empirical signatures of universality, hierarchy and clustering in culture
In this thesis,
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Establishing State Responsibility in the Absence of Effective Government
Op 16 juni 2020 verdedigde Andrea Varga haar proefschrift 'Establishing State Responsibility in the Absence of Effective Government'. Het promotieonderzoek is begeleid door promotoren prof. dr. N.J. Schrijver en prof. dr. F. Baetens (University of Oslo).
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The Monetary Valuation of Water-related Ecosystem Services
While ecosystems have concrete benefits for human society, these benefits are typically overlooked in decision-making.
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Explorations of Water Oxidation Catalysis in Explicit Solvent
In the search for sustainable energy solutions, the idea of artificial photosynthesis has been proposed as an approach with which to use water and sunlight to produce hydrogen.
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Self adjuvanting immunopeptides: Design and synthesis
Chapter 2 describes a post-synthetic methodology to introduce a fluorescent label in highly lipophilic, Pam3Cys based conjugates.
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Mass Spectrometry-Based Degradomics Analysis of Toxoid Vaccines
The chemical and structural heterogeneity of toxoid vaccines makes their analysis challenging. However, detailed insights on a molecular level can be obtained by mass spectrometry.
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Monsters in the Deep: Using simulations to understand the excess baryonic mass in the centres of high-mass, early-type galaxies
This thesis aims to enhance our understanding of galaxies by testing theoretical models of galaxy formation against observations, particularly in the cases of extreme systems which have been found to have an excess of baryonic mass in their central regions, in the form of either supermassive black holes…
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The Interactions of Human Mobility and Farming Systems and Impacts on Biodiversity and Soil Quality in the Western Highlands of Cameroon
Promotors: Prof.dr. G.R. de Snoo, Prof.dr. G.A. Persoon, Prof.dr.ir. H.H. de Iongh
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Crossed product algebras associated with topological dynamical systems
Promotor: S.M. Verduyn Lunel, Co-promotoren: M.F.E. de Jeu, S.D. Silvestrov
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Laboratory studies of Water Ice in Space
Astronomical observations of cold regions in the universe show a rich inventory of ices. Part of these ices may end up on planets like our own, but in that journey they will be exposed to considerable amounts of radiation.
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Inhibitors and probes targeting mannanases
This thesis describes the synthesis and biochemical evaluation of a variety of cyclophellitol based activity-based probes and inhibitors targeting various endo- and exo-acting retaining glycosidases. In the last two decades a variety of probes and inhibitors for (hemi)cellulose degrading enzymes have…
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Ab initio molecular dynamics calculations on reactions of molecules with metal surfaces
Promotor: Prof.dr. G.J. Kroes
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Another Brick in the Wall: The role of the actinobacterial cell wall in antibiotic resistance, phylogeny and development
Streptomyces are multicellular, Gram-positive bacteria in the phylum of actinobacteria which produce a high amount of bioactive natural products of which the expression is tightly coordinated with the life cycle.
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Novel pharmacometric techniques to quantify the pharmacodynamics of analgesics
The overarching clinical aim of this thesis was to improve pharmacological pain management by characterizing the pharmacodynamics of analgesics. This promotion has been awarded the predicate cum laude.
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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The Ornithology of the Baudin expedition (1800-1804)
The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.