707 zoekresultaten voor “quantum mechanisms” in de Publieke website
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Waar eindigt de quantumwereld?
Met zijn ijskoude nanokrachtsensor zoekt Tjerk Oosterkamp naar de grens tussen de quantumwereld en de wereld van alledag. De Leids natuurkundige heeft een NWO-subsidie van 600.000 euro binnengehaald.
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Regulation of actomyosin contraction as a driving force of invasive lobular breast cancer
In this thesis, we used genetically engineered mouse models and a variety of cell-culture based assays to identify genes and pathways that are involved in the development and treatment of invasive lobular carcinoma (ILC).
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Global distribution patterns of distinct mycorrhizal types and ecological drivers of these patterns
What are the global relationships between environmental conditions and abundance of distinct types of mycorrhizal fungi in soil and plant roots?
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Zebrafish as vertebrate model of Gaucher disease
Lysosomal storage disorders (LSDs) are a group of orphan diseases characterized by lysosomal dysfunction or impaired lysosomal catabolism and affect collectively about 1 in 5000 live births.
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Evolution and development of flowers, fruits and inflorescences of Phalaenopsis and other orchid species
The study of orchid flowers, fruits, and inflorescences is crucial due to the remarkable diversity of orchid species and their unique adaptations to pollinators and seed dispersers. However, our understanding of the evolution and development of these organs within the orchid family remains limited.
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Role of non-homologous end-joining in T-DNA integration in Arabidopsis thaliana
Promotor: P. J. J. Hooykaas Co-promotor: B. S de Pater
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Using mouse models to uncover genes driving tumorigenesis and therapy resistance in human breast cancer
To improve cancer treatments, personalized medicine approaches have aimed to identify exactly which mutations are driving tumor development in a given patient and specifically target these mutations using precision therapies.
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The electrochemical reduction of dioxygen and hydrogen peroxide by molecular copper catalysts
The electrochemical oxygen reduction reaction (ORR) is an essential half-reaction for the utilization of hydrogen as a sustainable fuel, via the conversion of hydrogen to electrons and protons facilitated by the ORR. In the most common fuel cells, the ORR is requires high loadings of non-abundant platinum…
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Like me or else...
Nature, nurture and neural mechanisms of social emotion regulation in childhood
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Green defense against thrips- Exploring natural products for early management of western flower thrips
As a contribution to the changing legislation and evolving societal attitudes concerning environmental issues, this project aims to enhance and manipulate the plants’ own natural defense mechanisms against western flower thrips (WFT).
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Accelerating the Photocatalytic Water Splitting in Catalyst−Dye Complexes
As a virtually inexhaustible source, solar energy plays a major role in future global energy scenarios.
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Fundamenteel onderzoek: Onderliggende mechanisme van ziekte en welzijn
Om de juiste klinische beslissingen te nemen of effectieve diagnostische testen en behandelingen te kunnen ontwikkelen, is het belangrijk om de onderliggende mechanismen van een aandoening of een bepaald gedrag te begrijpen.
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Understanding disease suppressive soils
Soil is a home for an unbelievable diversity and abundance of microbial life that is essential for supporting life on our planet.
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Lipid bilayers decorated with photosensitive ruthenium complexes
Promotor: Prof.dr. E. Bouwman, Co-promotor: S. Bonnet
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Compressed Σ-Protocol Theory
In analogy to mathematical proofs, the goal of a proof system is for a prover to convince a verifier of the correctness of a claim.
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Structure dependence of molecular reactions on surfaces
The research presented in this thesis makes use of small molecules (as H2 , D2 and O2 ) on well-defined single crystal surfaces (flat Pt(111), flat Cu(211) and curved Pt(111)) to elucidate the role of surface structure and degrees of freedom in the reactant in specific surface reactions.
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Thrips resistance in Gladiolus: an eco-metabolomic approach
Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.
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Quantitative systems pharmacology modeling of biotherapeutics in oncology
In this thesis, mathematical modeling and simulation was applied as a tool to inform quantitative decision making in oncology drug discovery and development.
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Regulering en ICT
Op welke manieren hebben ontwikkeling van digitale technologieën invloed op de samenleving en de regulerings- en juridische kaders binnen de samenleving?
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Novel factors modulating AGC kinase signaling-controlled polar auxin transport
The PID-directed shift in PIN polarity has been broadly accepted as one of the essential mechanisms for the regulation of auxin transport polarity.
- Today’s experimental quantum research at Leiden University: from the microscopic to the macroscopic
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Huub de Groot
Wiskunde en Natuurwetenschappen
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Florian Schneider
Gamic Learning in East Asian Studies - Wat kunnen spellen ons vertellen over de manier waarop mensen leren?
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Causing a stir: Radiative and mechanical feedback in starburst galaxies
Promotores: Prof.dr. F.P. Israel, Prof.dr. P.P. van der Werf
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Electrocatalytic reduction of CO2 and nitrate on immobilized metal porphyrins
M.T.M. Koper, Co-promotor: D.G.H. Hetterscheid
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CO oxidation catalysis at multiple length scales
Promotor: J.W.M. Frenken Co-Promotor: R. Felici
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The Chara plasma membrane system : an ancestral model for plasma membrane transport in plant cells
Multicellular giant algae Chara species have been widely used in physiological studies for decades.
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Morphogenesis and protein production in Aspergillus niger
Promotores: C.A.M.J.J. van den Hondel, V. Meyer, Co-promotor: A.F.J. Ram
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Search and rescue: tackling antibiotic resistance with chemistry
With the rise of multi-drug resistant bacterial pathogens, the possibility of a post-antibiotic world is quickly becoming reality.
- Epigenetica: of waarom een lapjeskat een lapjeskat is
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Klassieke opvatting in chemie blijkt onjuist
Célia Fonseca Guerra heeft samen met haar VU-promovenda Stephanie van der Lubbe quantumchemisch verklaard waarom het guanine-guanine basepaar kortere waterstofbruggen heeft en sterker gebonden is dan het cytosine-cytosine paar. Met haar ontdekking haalde Fonseca Guerra de Front Cover van het blad Chemistry…
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Breaking barriers: unraveling response mechanisms to immunotherapy in breast cancer
Promotie
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Een kunstmatig atoom als qubit
Bij een baanbrekend project als de quantumcomputer is het verstandig om niet op één paard te wedden. In de Leidse onderzoeksgroep Quantum Optics werkt men aan een ander type qubit dan op basis van het Majorana deeltje, gebaseerd op een 'kunstmatig atoom'. Als die de basis wordt van de quantumcomputer,…
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Temperature effects on genetic and physiological regulation of adaptive plasticity
Promotor: P.M. Brakefield
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Advances in SQUID-detected Magnetic Resonance Force Microscopy
In this thesis, we describe the latest advances in SQUID-detected Magnetic Resonance Force Microscopy (MRFM).
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Shining Light on PAHs in Space
Polycyclic aromatic hydrocarbons (PAHs) are the most abundant class of organic compounds in space. The PAH field evolves from the constant interaction between experimentalists, theorists, modellers and observers. While laboratory research and quantum chemical calculations together set up the molecular…
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Effects of heavy fields on inflationary cosmology
Promotor: A. Achúcarro, Co-Promotor: J.W. van Holten
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Photothermal studies of single molecules and gold nanoparticles: vapor nanobubbles and conjugated polymers
Promotor: M.A.G.J. Orrit
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Photon detection at subwavelength scales
Promotor: Prof.dr. E. Eliel, Co-Promotor: M.J.A. de Dood
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Plasmonic enhancement of single-molecule fluorescence under one- and two-photon excitation
This thesis aims to improve the detection from ultra-weak single emitter by enhancing their emission properties with plasmonic nanostructures. We exploit the wet-chemically synthesized single crystalline gold nanorods (GNRs) as our basic frameworks in the whole studies, simply because of their unique…
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The lead zeppelin: a force sensor without a handle
Promotor: T. H. Oosterkamp
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Theorie van fermion-pariteit-omkeringen in supergeleiders
Majorana ontmoet een zeemeermin
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Low energy electron transmission through layered materials and chiral organic films
In this Ph.D. thesis we study the interaction of low energy electrons with thin materials, namely layered materials (graphene, hexagonal boron nitride, molybdenum disulfide) and organic films. At these low energies the quantum mechanical wavelength of the electron wave function is in the order of a…
- Universiteit Leiden
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Center for Interdisciplinary Placebo Studies Leiden
Het Center for Interdisciplinary Placebo Studies Leiden (IPS) streeft naar een beter begrip van placebo- en nocebo-effecten, hun onderliggende mechanismen en hun mogelijke toepassingen in de klinische praktijk. IPS bestaat uit een groep interdisciplinaire onderzoekers die werken aan de Universiteit…
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Het lerarentekort als gewichtige uitdaging: Schoolleiderschap, werkklimaat en leerklimaat op scholen met een hoge schoolweging.
Welke rol spelen de leiderschapsstijl en de visie op leraren en leerlingen van schoolleiders in het bevorderen van een positief werkklimaat voor leraren en een positief leerklimaat voor leerlingen op scholen met een hoge schoolweging?
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Synthetic modification of fusogenic coiled-coil peptides
A structural investigation of coiled coil peptides used as membrane fusogens, mimicing naturally occuring coiled-coil fusion proteins. Synthetic modifications have been made to alter lipid attachment, secondary structure and to insert photoactive azobenzene moieties for active control over coiled coil…
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Evolutionary diversification of Nepenthes (Nepenthaceae)
Promotor: Erik F. Smets, Co-promotores: Barbara Gravendeel, Niels Raes
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Core cross-linked polymeric micelles based on polypept(o)ides: from secondary structure formation of polypeptides to functional cross-linking
This thesis aimed to investigate core cross-linked polymeric micelles (CCPMs) and expand their potential for the delivery of hydrophobic drugs and co-factors.
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'Q-wires': Synthesis, electrochemical properties and their application in electro-enzymology
An objective of this research was to achieve direct, well-defined and non-rate-limiting electron transfer between respiratory enzymes and the electrode surface by means of 'Q-wires'.