3,763 zoekresultaten voor “leiden institute for brain and cognition” in de Publieke website
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Intermittency and Number Expansions for Random Interval Maps
This dissertation consists of two parts, each of which considers a different research area related to random interval maps. In the first part we are interested in random interval maps that are critically intermittent.
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Inverse problems for universal deformation rings of group representations
Promotor: Prof.dr. P. Stevenhagen
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Development of life cycle assessment for residue-based bioenergy
Wat zijn de belangrijkste thema's in het uitvoeren van systemen voor bio-energie ?
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Development of an Adverse Outcome Pathway (AOP) for metallic nanoparticles
What is the mechanism of action preceding a physiological effects induced by metallic nanoparticles?
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Network analysis methods for smart inspection in the transport domain
Transport inspectorates are looking for novel methods to identify dangerous behavior, ultimately to reduce risks associated to the movements of people and goods. We explore a data-driven approach to arrive at smart inspections of vehicles.
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Mechanism-based inhibitors and probes for neuraminidases
Neuraminidases are enzymes that cleave glycosidic linkages of sialic acid. These enzymes are involved in influenza infections as well as in many cellular processes in mammals and micro-organisms.
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Targeted Therapy for Triple-Negative Breast Cancer
The research described in this thesis focused on identifying novel drug targets and synergistic combinations for triple-negative breast cancer (TNBC), a virulent subtype of breast cancer with a dismal prognosis and limited therapeutic options.
- Elastin-like polypeptide micelles for vaccine delivery
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Taking control of charge transfer: strategic design for solar cells
Promotor: Huub J.M. de Groot, Co-promotor: Francesco Buda
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Terrestrial field trials for side-effects of pesticides
The thesis describes terrestrial field trials aimed to detect side-effects of pesticides within the framework of pesticide registration procedures. Field trials were developed using vascular plants Brassica napus and Poa annua, caterpillars Pieris brassicae and effects on decomposition were studied…
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Diagnostics for mechanical heating in star-forming galaxies
Promotor: F.P. Israel, Co-Promoter: R. Meijerink
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Chemistry in embedded disks: setting the stage for planet formation
To address the fundamental questions of how life on Earth emerged and how common life may be in the Universe, it is crucial to know the chemical composition of the planet-forming material.
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Development of life cycle assessment for residue-based bioenergy
Promotores: Prof.dr.G.R. de Snoo and Dr. R. Heijungs
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Biomimetic Copper Catalysts for the Electrochemical Oxygen Reduction Reaction
Human civilization consumes a huge amount of fossil fuels, which has resulted in an atmospheric CO2 level which has not been higher in over 800 millennia.
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Meta-heuristics for vehicle routing and inventory routing problems
Promotores: T.H.W. Bäck, Y. Tan, Co-promotor: M.T.M. Emmerich
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Civil Liability for Damage caused by Global Navigation Satellite System
Op 17 december 2018 verdedigde Dejian Kong zijn proefschrift 'Civil Liability for Damage caused by Global Navigation Satellite System'. Het promotieonderzoek is begeleid door promotor prof. dr. P.M.J. Mendes de Leon.
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Collaborative learning in conservatoire education: catalyst for innovation
Het doel van dit proefschrift is om eerst te onderzoeken welke vormen van samenwerkend leren bij de verschillende conservatoria in de praktijk worden gebracht, om vervolgens te kijken naar hoe samenwerkend leren kan worden geïmplementeerd.
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Benefit for all – Een ecosysteem voor een gezonde levensstijl
Het BENEFIT-programma is een publiek-privaat ecosysteem in een nationaal consortium, met als doel patiënten met cardiovasculaire aandoeningen langdurig in hun eigen thuissituatie te ondersteunen bij een gezonde leefstijl.
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Novel chemical tools for target validation in neuroinflammation
Stelt
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A Multi-Level Leadership Spectrum for Collective Good
In dit artikel bespreken Ben S. Kuipers en Joanne Murphy recente kritieken op de theorie en praktijk van leiderschap.
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George Miley
Wiskunde en Natuurwetenschappen
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Non-take-up of social support and the implications for social policies
This dissertation takes an important step in understanding the phenomenon of non-take-up of social support and what it means for contemporary social policies.
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Modulation of the immune system for treatment of atherosclerosis
Cardiovascular diseases are the primary cause of death in the world with atherosclerosis as primary underlying cause.
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Strategies for the improvement of genome editing in Arabidopsis thaliana
Increasing the efficiency of gene targeting (GT) as a genome editing tool in plants has been an important goal in plant biotechnology.
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An Algebra for Interaction of Cyber-Physical Components
Modeling and analysis of cyber-physical systems are still challenging. One reason is that cyber-physical systems involve many different parts (cyber or physical), of different nature (discrete or continuous), and in constant interaction via sensing and actuating.
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Lipids as therapeutic targets for barrier repair in skin diseases
The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.
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Minor Creative Strategies for a Society in Change
De minor Creative Strategies for a Society in Change (CSSC) legt een verbinding tussen het verkrijgen van inzicht in creatieve maakprocessen en het verkennen van maatschappelijke problematieken die kenmerkend zijn voor onze tijd.
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800 mensen kijken in de wereld van het sociale brein
‘Of we nog een beetje kunnen aanschuiven, dan passen we er allemaal in.’ Uit het hele land komen mensen voor een interactieve dag over het sociale brein. Zes breinwetenschappers weten wat er leeft, blijkt op 6 november j.l. tijdens het publiekssymposium van het Leiden Institute for Brain and Cognition…
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A novel supramolecular system for membrane fusion and biosensing
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A renewed awareness: Reinvigoratingpreparedness research for crisis and disastermanagement
IIn dit artikel blazen Jeroen Wolbers en Sanneke Kuipers het academische debat over rampenparaatheid nieuw leven in.
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Novel target engagement biomarkers for better drug candidates
M van der Stelt
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Cytochrome C Oxidase mimics for use in catalytic water oxidation
Hetterscheid
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Leiden University Centre for the Arts in Society
Het Leiden University Centre for the Arts in Society (LUCAS) is wereldwijd een van de weinige onderzoeksinstituten waar wetenschappers op het gebied van literatuur, beeldende kunst, architectuur, design en mediastudies samenkomen om onderzoek te doen naar de culturele productie van de westerse wereld,…
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Ice and Gas in Protostellar Clouds and Planet-forming Disks
This thesis takes steps toward understanding the interaction between gas-phase and solid-state molecules in star- and planet-forming regions.
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Call for Papers and Panels: Global Transformations and Governance Challenges (GTGC) Conferentie 2023
Van 7-9 juni 2023 organiseert Global Transformations and Governance Challenges (GTGC) haar tweede internationale conferentie in Den Haag. Deadline voor inzendingen: 15 februari 2023.
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Paul Wouters
Faculteit der Sociale Wetenschappen
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The synthesis of chemical tools for studying sphingolipid metabolism
Sphingolipids are important membrane compounds with a variety of functions. In mammalian cells, different enzymes are involved in the metabolism of sphingolipids, but interruption of this metabolism process leads to different diseases.
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Addressing Environmental Concerns Through Trade: A Case for Extraterritoriality?,
Kunnen landen bij gebrek aan een sterk internationaal kader voor milieubescherming unilateraal optreden om het wereldwijde milieu te beschermen?
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Squaramide-based supramolecular materials for 3D cell culture applications
A new type of tripodal squaramide-based supramolecular hydrogels is developed and studied.
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Reliable and Fair Machine Learning for Risk Assessment
The focus of this thesis is on the technical methods which help promote the movement towards Trustworthy AI, specifically within the Inspectorate of the Netherlands.
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High-throughput quantification and unambiguous identification for metabolomics
The challenge of achieving fast quantification in metabolomics is the presence of severe matrix effects during the MS analysis of complex samples.
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Interaction with sound for participatory systems and data sonification
This thesis deals with the use of sound in interactions in the context of participatory systems and data sonification. We investigate an interactive environment where participants perceive information of the data through sound elements.
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Hunting for new physics in the primordial Universe
This thesis contributes to studying primordial cosmology theories and their detectability in future observations.
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Advancements of interventional oncology treatments for early stage hepatocellular carcinoma
Promotie
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Waarom positieve emoties zo belangrijk zijn
‘Een goudmijn aan kennis over positieve emoties’, zo noemt cognitief neurowetenschapper Henk van Steenbergen de speciale overzichtsuitgave van het vakblad Current Opinion in Behavioral Science. 'Het is een mooi voorbeeld van team science.' Bijdragen van 34 internationale experts helpen het onderzoeksgebied…
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Exploring Images With Deep Learning for Classification, Retrieval and Synthesis
In 2018, the number of mobile phone users will reach about 4.9 billion. Assuming an average of 5 photos taken per day using the built-in cameras would result in about 9 trillion photos annually.
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Deep learning for tomographic reconstruction with limited data
Tomography is a powerful technique to non-destructively determine the interior structure of an object.Usually, a series of projection images (e.g.\ X-ray images) is acquired from a range of different positions.
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Stochastic and Deterministic Algorithms for Continuous Black-Box Optimization
Continuous optimization is never easy: the exact solution is always a luxury demand and the theory of it is not always analytical and elegant.
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A recipe for desert: analysis of an extended Klausmeier model
Promotores: Arjen Doelman, Jens Rademacher, Max Rietkerk
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Novel detectors and algorithms for electron nano-crystallography
Promotor: Prof.dr. J.P. Abrahams, Prof.dr. M. van Heel