With the energy transition toward a renewable energy supply and a CO2-neutral economy, electrification of the energy system is rising in importance, which leads to the challenge of long-term storage of renewable electricity.

The skin is our natural barrier and lipids are a key part of this barrier. In the outer skin layer, the stratum corneum (SC), lipids form a densely organized structure dependent on the composition of these lipids.

New drugs for use as tuberculosis (TB) treatment are needed due to the constrains of classical antibiotics against TB and the rise of antibiotic-resistant strains, making TB a harder and harder disease to treat.

Op 11 november 2021 verdedigde Mariana Gkliati het proefschrift 'Systemic Accountability of the European Border and Coast Guard'. Het promotieonderzoek is begeleid door promotoren prof.dr. P. Rodrigues en prof.dr. L. Besselink (UvA).

This thesis is dedicated to the exploration of the primordial dark ages: unknown physics during the earliest stages of the Universe’s expansion that have not yet been directly probed by observations. Cosmic inflation is a burst of exponential expansion of space after the “Big Bang”.

Promotor: F.J. van Lunteren, E. Jorin

Assessing the risks of engineered nanomaterials (ENMs) solely on the basis of experimental assays is time-consuming, resource intensive, and constrained by ethical considerations (such as the principles of the 3Rs of animal testing). The adoption of computational toxicology in this field is a high p…

Circumstellar discs are the reservoirs of gas and dust that surround young stars and have the potential to become planetary systems.

The focus of the described research in this thesis is on the oxidative stress response (Nrf2 pathway). The aim of the research presented in this thesis is to obtain more information concerning microRNAs which are involved in the Nrf2 pathway, to determine and evaluate the application of microRNAs for…

Promotores: Prof.dr. T.H.W. Bäck, Prof.dr. M. Bongards (Cologne University)

Phosphorylation affects all four major biomolecules – proteins, lipids, carbohydrates and nucleic acids – and plays a pivotal role in the most fundamental cellular functions.

During embryonic growth, cells proliferate, differentiate, and collectively migrate to form different tissues at the right position and time in the body.

Breeding for resistance becomes more and more important because we want to reduce the use of pesticides. A fast and cheap alternative can be to make use of morphological or chemical markers.

The majority (80%) of e-waste generated globally are recycled informally in developing countries.

This thesis focuses on using liposomes in two different treatment strategies; vaccination (or immunotherapy) and delivery of a small molecule, and in two different disease models; cancer and atherosclerosis.

Promotor: Prof.dr. H. J. A. Röttgering, Co-Promotor: M. Haverkorn

Giles Scott-Smith, 'Interdoc. Een geheim netwerk in de Koude Oorlog' (Amsterdam 2012) Uitgeverij Boom.

In populations with a seed-bank, individuals can temporarily become dormant and refrain from reproduction until they can become active again. The repository of all dormant individuals in the population is called the seed-bank. Seed-banks are observed in many taxa, including plants, bacteria and other…

Investigating neurobiological endophenotypes of Social Anxiety Disorder

1. To what extent do metallic NPs added to soil extractions change the activity, abundance, or community composition of microbes? 2. How do the effects of metallic NPs on soil microbes differ from the effects of the ions shedding from corresponding NPs?

Het Leiden Leadership Centre verbindt wetenschap en praktijk door evenementen over publiek leiderschap te organiseren – zoals Leiden Leadership Lunches, webinars, (internationale) conferenties en de Leiden Leadership Podcast.

Dit proefschrift onderzoekt de noodzaak van het creatief denken en experimenteren in het uitvoeren van complexe muziek in de late twintigste- en vroege eenentwintigste eeuw.

For centuries astronomers studied the Universe by collecting light. Nowadays, we are living in times of great technological advancements, which allow us to explore our Universe in a new way - though gravitational wave radiation.

This thesis systematically studies the physicochemical properties of non-planar, propeller-shaped, polycyclic aromatic hydrocarbons. The synthesis of several so-called propellerenes is described on a gram scale, using optimized procedures aimed at using less hazardous reagents and reducing the amount…

Leiden is een echte studentenstad. Meld je aan voor een studievereniging of studentenvereniging om van jouw studietijd een onvergetelijke tijd te maken!

The work described in this dissertation contributes to a better mechanistic understanding of nanoparticles in vivo. To achieve that goal, we used the zebrafish as a highly predictive pre-screening model of nanoparticles.

The stratum corneum is the outermost skin layer and consists of dead cells embedded in a lipid matrix.

Leiden University College The Hague (LUC) biedt een 3-jarige bacheloropleiding aan waarin je je focust op Global Challenges; grote uitdagingen waar de mensheid mee te maken heeft: Vrede & Rechtvaardigheid, Diversiteit, Duurzaamheid en Welvaart. Je hebt ruimte om de opleiding zo in te richten als je…

Op 11 oktober verdedigde Amanda Pasma het proefschrift 'Re-integratieondersteuning van interne en externe professionals tijdens detentie'. Het promotieonderzoek is begeleid door Paul Nieuwbeerta, Hanneke Palmen en Esther van Ginneken.

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

Loopbaan en solliciteren

Promotie

Kennis van moslimsamenlevingen is onmisbaar om in een geglobaliseerde wereld te kunnen functioneren en om onze eigen Nederlandse maatschappij goed te begrijpen. In Leiden verdiepen onderzoekers zich in de talen, cultuur, religie, rechtssystemen en geschiedenis van moslimsamenlevingen en zetten daarmee…

The project

Participants in this course will learn to support student teachers and new colleagues in their professional development as teachers, with particular emphasis on the context of bilingual or international education, as in the ICLON World Teachers Programme (WTP).

Inverse problems are problems where we want to estimate the values of certain parameters of a system given observations of the system. Such problems occur in several areas of science and engineering. Inverse problems are often ill-posed, which means that the observations of the system do not uniquely…

Simone van der Hof heeft voor Privacyweb een blog geschreven over de online-privacy van kinderen.

In Leiden gaat op 30 mei de eerste ScienceOnline-community in West-Europa van start. ScienceOnline is een nieuwe community voor wetenschap en online communicatie.

Onze onderzoeker en promovenda Helena Ursic heeft een interview gegeven aan Druzina, één van de grootste kranten in Slovenië.

Studievoorlichting

Uniting an international consortium of scholars, the Skandapurāṇa Project comprises a team of researchers working in fields across the Humanities. We are creating a critical edition of a foundational work of purāṇic literature and, in doing so, tracing the dynamics of a textual tradition to better understand…

Informaticadeskundige Frank Takes onderzocht efficiëntere manieren om in sociale netwerken van A naar F te komen. Daarvoor presenteert hij algoritmen die anderhalf jaar rekenen kunnen terugbrengen tot slechts een paar seconden. Promotie op woensdag 19 november.

Geschiedenisstudente Willemijn kreeg twee maanden geleden corona. Op dat moment volgde ze een vak van docent Rens Tacoma. Hoe moet het met je studie als je zelfs te ziek bent om online colleges te volgen? En hoe ga je als docent om met steeds meer zieke studenten? ‘We moeten dit echt samen doen.’

Simone van der Hof heeft voor het Rathenau Instituut een blog geschreven over de bescherming van de privacy van kinderen.