How can we develop and further improve life cycle impact assessment methods, characterisation factors and normalisation factors?

Making a dynamic substance stock model in order to conduct scenario analyses and make forecasts.

Promotor: J.M. van Ruitenbeek, Co-Promotor: S.J. van der Molen

Promotor: Prof.dr. M. de Jong

Promotores: Prof.dr. G. Miley & Prof.dr. J.M. van den Broek

Lysosomal acid glucosylceramidase (GBA1) is a lysosomal enzyme that degrades glucolipids with its main substrate being glucosylceramide (GlcCer). Defects in the GBA1 gene lead to glycosphingolipidosis Gaucher disease (GD), in which the hydrolysis of GlcCer is impaired and therefore, it accumulates in…

Sound is everywhere in the marine environment and hearing is therefore a very important for stimuli for fish. They use sound for orientation and communication, during migration, aggregation and spawning, but also for detection of prey and predators.

Promotor: B.van de Water, Co-promotor: L.S.Price

The marine shipping industry is one of the strongest emitters of nitrogen oxides (NOx), a pollutant detrimental to ecology and human health. Over the last 20 years, the pollution produced by power plants, the industry sector, and cars has been decreasing.

The main subject of this thesis is the design and synthesis of paramagnetic molecules for protein studies with NMR and EPR spectroscopy.

Promotor: Prof.dr. A. P. IJzerman, Co-Promotor: L.H. Heitman

Promotor: T. Schmidt, Co-promotor: S. J.T. van Noort

Celebrating 20 years of environmental research in Cagayan Valley and Sierra Madre

Promotor: H.V.J. Linnartz

This PhD research sets out to unravel and explain the socio-structural and cultural impacts of oil-industrialization on the local Bakhtiari community in general and the industrial laborers it provided in specific.

In this thesis new methodologies are developed for the detection and systematic study of radio sources in the early universe. This allows us to gain a deeper understanding of the formation and evolution of galaxies, the activity of supermassive black holes, and the final phase transition of our universe:…

It has been a long-standing mystery how complex biological structures emerge from such seemingly uncoordinated building blocks as cells and tissues, in the presence of only minimal environmental guidance.

Promotor: G.J. Kramer Co-Promotor: E.G.M. Kleijn

There is accumulating evidence for an increase in severe global drought events. In particular, Europe experienced several severe droughts in 2003, 2015, and 2018 (unprecedented in the past 2,110 years). Such droughts have caused serious and far-reaching impacts on terrestrial ecosystems.

In this thesis we study products of linear error correcting codes.

Promotor: T. Schmidt, Co-Promotor: B.E. Snaar-Jagalska

This thesis describes the development and optimization of the first molecular tools to study the enzyme PLA2G4E.

Sewer pipes are an essential infrastructure in modern society and their proper operation is important for public health. To keep sewer pipes operational as much as possible, periodical inspections for defects are performed.

Universitaire plechtigheid

Journalisten zijn niet tevreden over de afhandeling van Woo-verzoeken. Deze duurt vaak lang, levert soms weinig op en de communicatie kan volgens hen beter.

‘Samenwerking wordt steeds belangrijker’, zei rector magnificus Carel Stolker op 7 februari tijdens de 445ste dies natalis van de Universiteit Leiden. Maar, zo hoorde hij van een aantal Leidse wetenschappers, dat kan alleen vanuit een sterke eigen discipline. Een novum was de gezamenlijke diesoratie…

Les van een hoogleraar op de basisschool, bijvoorbeeld over de geschiedenis van Afrika, het klimaat of over zorg en onderzoek. Honderd Leidse hoogleraren lieten kinderen kennismaken met hun werk in het project Meet The Professor.

De keten die patiënten voorziet van nieuwe medicijnen, bestaat uit diverse complexe schakels: van fundamentele wetenschap, tot klinische tests, tot productie. Deze hele keten is aanwezig in Leiden. De Universiteit Leiden, het Leids Universitair Medisch Centrum (LUMC) en de bedrijven op het Leiden Bio…

Plants and their pollinators form complex interaction networks. Within these networks, species differ widely in the number of species they interact with.

To get an idea of the science communication products and research that is possible, a few examples of student projects of recent years are shown below.

The field of exoplanet research is rapidly advancing through the development of new technology, observing techniques, and post-processing methods.

Promotor: Prof.dr. T.H.W. Bäck

The expedition commanded by Nicolas Baudin to Tenerife, Mauritius, Australia, Timor and South Africa in 1800-1804 is fully researched in regard to ornithology.

Promotor: Prof.dr. J. Kuiper

Op 28 oktober 2021 verdedigde Hein van der Bruggen zijn proefschrift en behaalde daarmee de doctorstitel.

The Vallesian, 11.1-9 Ma, was a special time in the Vallès-Penedes basin near Barcelona, where a biodiversity hotspot existed. Europe had a subtropical climate, with rhinos, forest giraffes, lions, hyenas, flying squirrels and primates.

Promotor: Prof.dr. M. Ubbink

Promotor: Prof.dr. H.S. Overkleeft

Op 11 juni 2020 verdedigde Sabine Witting haar proefschrift 'Child Sexual Abuse in the Digital Era: Rethinking Legal Frameworks and Transnational Law Enforcement Collaboration'. Het promotieonderzoek is begeleid door promotoren prof.mr. J.J. Sloth-Nielsen en prof.dr.mr. S. van der Hof.

Promotor: J.S. Kaastra Co-promotor: E. Constantini

Promotor: M.K. Richardson, Co-Promotor: F. Witte

This PhD thesis concerns the topic of arithmetic geometry. We address three different questions and each of the questions in some way is about counting how big some set is or can be.

De afdeling Bedrijfswetenschappen houdt zich bezig met vraagstukken op het gebied van ondernemerschap, organisatiepsychologie en insolventie. Op de afdeling werken docenten en onderzoekers uit verschillende disciplines, zoals marketing, economie, finance, strategie en de gedragswetenschappen.

This thesis studied in depth the energy use and CO2 emissions of the industrial sector in China.

Tracing the evolution of the molecular gas content in galaxies is critical for a complete understanding of galaxy formation and evolution, as it provides the direct fuel for star formation. Studies of high-redshift (z>1) molecular gas reservoirs, most commonly traced by carbon monoxide (CO), have seen…

Developing robust algorithms and theory for establishing cause-effect relationships from observational data that scale up to large data sets

Low-carbon (LE) technologies have a significant potential to reduce the total carbon emissions in China.

Promotores: Prof.dr. E.F. van Dishoeck, Prof.dr. C.P. Dullemond

The growing demand of energy indicates that global energy resources in the form of fossil fuels will not be sufficient in the future. In order to solve potential future energy problems development of a sustainable hydrogen economy is highly desirable.