An international group of scientists has discovered that certain cells of our immune system – the so-called T cells – communicate with each other and work together as a team. To fight an infection they stimulate each other’s growth, but at the same time, they inhibit each other when there is a surplus…

Stimulating the vagus nerve, which provides a direct link between the gut and brain, makes people pay less attention to sad facial expressions. This research study by psychologists Katerina Johnson and Laura Steenbergen is published in the journal Neuroscience.

PhD student Wen Yang discovered how certain cell receptors in E. coli bacteria signal 'smells'. With the use of ice-cold electron microscopy microbiologists from Leiden gain more insight into how bacteria respond to their environment. Publication in mBio.

Leiden University is partner of the Netherlands Centre for One Health (NCOH). This initiative brings together leading academic research institutes in the Netherlands in an open innovation network that responds to the theme: One Health. NCOH interviewed Doris van Bergeijk: PhD student of the project…

The Faculty Council is the most important co-participatory body of the Faculty of Archaeology. Its members represent staff and students in meetings with the Faculty Board, and they can have a profound impact on the Faculty's policies. We speak with the council's chair, Merlijn Veltman, about the goals…

In the Netherlands, anyone who loses their passport or ID card too often can be added to the Passport Alerts Register. As a result, a passport application may be denied or the passport must be surrendered. Rowie Stolk, PhD candidate at the Department of Constitutional and Administrative Law, spoke on…

Northern lights, stellar winds and exoplanets. This is what astronomer's PhD research revolved around. PhD candidate astronomer Rob Kavanagh developed mathematical models to better understand the interactions between exoplanets and stellar winds and to define features of exoplanets. He will receive…

Seven Leiden researchers have been awarded a prestigious Vici grant by the Netherlands Organisation for Scientific Research (NWO).

Hoping to learn something about the human brain, Leiden researchers are creating a setup to shoot single photons, particles of light, into someone’s eye. ‘The eye is a passageway to the brain.’

PhD defence

For the first time ever, Leiden biologists have found that the ‘nose’ of spirochetes – worm-shaped bacteria – have a two-fold symmetry. A remarkable discovery, as the ‘nose’ of every other bacterium has been found to have a six-fold symmetry. First author Alise Muok wrote a popular blog about the findings…

For centuries, astronomers have studied the universe by collecting light signals. Since 2015, the confirmation of an important prediction of Einstein allows us to explore the universe in a new way: through gravitational wave radiation. Astronomy PhD candidate Valeriya Korol proposes to use these gravitational…

Researchers at Leiden University and TU Delft have combined two techniques that are used to measure the structure of biomolecules, creating a method that is ten times more sensitive.

An important discovery makes it possible to communicate complex information among multiple people without the message being cracked. The communication can also relate to complex information.

The intestinal bacterium E. coli can adapt to changes in its surroundings. Leiden scientists have discovered how the H-NS protein makes this possible. This new knowledge can be an important starting point in combatting bacteria and diseases such as peritonitis. Publication 2 October in the journal e…

Sonja Boas developed new techniques to study vascular growth computationally. The results of her research provide a better understanding into mechanisms behind vascular growth, which is relevant to the development of medical therapies. She defends her thesis 'Computational modeling of angiogenesis'…

That a switching protein plays a role in protecting a plant from too much sunlight was already known, but how exactly was not yet understood. The research group of Anjali Pandit has now discovered that this protein changes shape when there is too much sunlight. The results have been published in Nature…

Leiden biophysicists have found a new possible way to attack cancer cells. They have located ‘sinkholes’ on the cells where receptor proteins disappear from the surface. If a drug could push these proteins towards those areas, it would kill the cancer cell.

Tracking early human behaviour through plant processing and -exploitation.

Methods of treatment for chronic illnesses are limited. Doctors and researchers at Leiden University Medical Center (LUMC) and Leiden University are working on new therapies as an alternative for organ transplants. The goal is to cure the illnesses by restoring organs to their original function. Stem…

Through metabolism, biochemical processes give rise to the complexity of life. Acquired and inborn errors in metabolism underlie many diseases occurring in man. The challenge for present day medical biochemistry is to find, and integrate, pieces of information at molecular, cell and organismal level…

A neural network mimics how our brain works. Evolutionary algorithms use the principle of natural selection to solve complex problems. This kind of 'natural computing' is being used to improve the diagnosis of Parkinson's disease or the production of steel.

Research at the Macromolecular Biochemistry group is comprised of the following research themes:

Issue 1

Plants, algae and cyanobacteria have the amazing capacity to perform delicate photophysical and photochemical processes of light capture, excitation transfer, charge separation and catalysis in fluctuating living environments. As a consequence, photosynthetic proteins and membranes form dynamic architectures.…

My ERC Starting Grant, funded with €1.5 million for 5 years as part of the Horizon 2020 research and innovation program, is focused on building the early warning system WARN-D to reliably forecast depression in young adults before it occurs. Why depression, and why prediction?

Allosteric modulation has long been recognized as a general and widespread mechanism for the control of protein function. Modulators bind to regulatory sites distinct from the active site on the protein, resulting in conformational changes that may profoundly influence protein function. This concept…

An Investigation into the role of copper-alloy craft production in the early medieval economy of northwest Europe.

Efficiently responding to others’ emotions has great survival value, especially for social species, such as primates, who establish close, long-term bonds with group members. The closest living relatives to humans are the chimpanzee and the bonobo. Studying these species, and comparing them on the exact…

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The need for novel drugs as well as innovations in their development and application is as urgent as ever. Below we present our vision , mission, and our key research areas.

Ships are still emitting too much nitrogen oxide. Till now it has been impossible to measure this at sea, but that is set to change. Solomiia Kurchaba combined satellite data and developed algorithms to identify which ships are emitting too much. Kurchaba received her PhD on 11 June.

During the congress of the Royal Dutch Association for the Advancement of Pharmacy (Koninklijke Nederlandse Maatschappij ter bevordering der Pharmacie, KNMP) Jacqueline Gerritsen, former student Bio-Pharmaceutical Sciences at Leiden University, was awarded the KNMP student prize.

On October 26, the Dutch Embassy in Berlin celebrated the opening of a new research network for Dutch academics in Germany. Dutch minister of Education, Culture and Science Robbert Dijkgraaf gave the starting signal for this new initiative.

Hundreds of millions of Chinese workers have moved from the countryside to the city. This social transformation has birthed a tradition of migrant worker poetry, professor Maghiel van Crevel states in Jacobin.

In 2012 the Pascal chair of the Faculty of Science of Leiden University, and particular of Leiden Institute of Advanced Computer Science (LIACS), will be held by Prof. Dr. Kyle Gallivan, Department of Mathematics, Florida State University, USA.

Social Psychologist Angelo Romano have been awarded the Association for Psychological Science (ASP) Rising Star designation. This award is presented to outstanding APS members in the earliest stages of their research career post-PhD.

Op maandag 1 april 2024 stierf onze leermeester, vriend en gewaardeerd collega Dr. Alexander Hendrik de Groot (Sander).

Industrial ecologists Stefano Cucurachi and Flora Siebler are part of the new consortium PROGENY, which received 3.6 million euros from the European Commission. PROGENY is an exciting project that will study the possibilities of soap films for innovations, such as ultra-thin screens.

Exactly a century ago, astronomers observed the first two diffuse interstellar bands (DIBs) in space. A DIB manifests itself as a colour of light that is missing in the radiation from stars behind an interstellar cloud. Although about 500 DIBs are yet discovered, they remained inexplicable until recently.…

What is the influence of non-hereditary factors on our health, such as lifestyle, diet and exposure to harmful substances? The Exposome-Scan project, led by Leiden professor Thomas Hankemeier, has been awarded 3.2 million euros from the NWO Investment Grant Large programme to answer this question. With…

Observations made with the ALMA telescope in Chile and ESA’s Rosetta mission, have detected the faint molecular fingerprint of methyl chloride in gas, a chemical commonly produced by industrial biological processes on Earth, around both an infant star and a comet. Methyl chloride, also known as Freon-40,…

Three new ministries have been formed in the Netherlands: Asylum and Migration, Housing and Spatial Planning & Climate and Green Growth. Of course, this is not merely an administrative act. These ministries carry a strong and political charge and play a crucial role in shaping a government's political…

Chemist Roxanne Kieltyka has received an ERC Starting Grant of 2 million euros. In her lab, she creates gels that mimic the instructive material that supports cells in our body. With the grant, she aims to make these gels stiff and tough, and to create a bio-printed miniature heart ventricle.

The Leiden Science Run 2019 has raised a record sum of 12,135 euros for refugee student foundation UAF. No less than 101 teams – also a record – and the sponsors CORPUS and Janssen Biologics raised the amount.

Although Sander Wezenberg just started working in Leiden in March this year, he already managed to win a Vidi grant from NWO. Inspired by nature, Wezenberg wants to bring synthetic molecules to life and teach them to communicate. But who exactly is Wezenberg and what drives him?

Heavy rainfall can cause streets to flood and basements and tunnels to overflow. Jan van Rijn investigated, together with Christiaan Lamers (formerly of Leiden University) and Ton Beenen (STOWA, RIONED), how data science can help to predict which areas are at greater risk of flooding. Van Rijn presented…

In 2015, Jorryt Matthee thought he discovered an extremely distant galaxy called CR7, which lacked elements heavier than helium. Three years later, he shows with measurements using the ALMA telescope that the galaxy does have carbon after all, and even in normal concentrations. The American Astronomical…

‘It's empty talk, nothing but political posturing,’ says Prof. Leo Lucassen about Minister Lodewijk Asscher's plan for a participation contract for migrants. ‘It will never happen.’ Lucassen, Leiden specialist in History of Migration, discussed Asscher’s Integration Letter on the NTR programme De Halve…